UCSF

Integrin Alpha-4, Human (769 Compounds)

Swissprot:
ITA4_HUMAN
Stitch:
ITA4_HUMAN
UniProt:
P13612
ChEMBL:
CHEMBL278
Reactome:
REACT_12051
REACT_11152
REACT_13552
PDB:
3V4P (DOCK)
3V4V (DOCK)
ITGA4

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 769 9 0 0
Binding ≤ 1μM 678 4 0 0
Functional ≤ 10μM 50 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_12051 Cell surface interactions at the vascular wall Homo sapiens
REACT_11152 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens
REACT_13552 Integrin cell surface interactions Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 158

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Uniprot Swissprot Chembl Description Number Shared
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 158
ITB7_HUMAN P26010 CHEMBL2979 Integrin Beta-7, Human 381
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 279

Integrin cell surface interactions

Uniprot Swissprot Chembl Description Number Shared
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 1
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 158
ITB7_HUMAN P26010 CHEMBL2979 Integrin Beta-7, Human 381
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 279
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 1,479 4 8 8
ITA2_HUMAN P17301 CHEMBL4998 Integrin Alpha-2, Human 32 0 0 0
ITA3_HUMAN P26006 CHEMBL3525 Integrin Alpha-3, Human 0 0 0 0
ITA5_HUMAN P08648 CHEMBL3955 Fibronectin Receptor Alpha, Human 67 2 0 1
ITAL_HUMAN P20701 CHEMBL1803 Leukocyte Adhesion Glycoprotein LFA-1 Alpha, Human 471 24 2 1
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 434 0 0 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ITB7_HUMAN P26010 CHEMBL2979 Integrin Beta-7, Human 381
VCAM1_HUMAN P19320 CHEMBL3735 Vascular Cell Adhesion Protein 1, Human 279
Z104293 Z104293 CHEMBL1907599 Integrin Alpha-4/beta-1 257
ITB1_HUMAN P05556 CHEMBL1905 Fibronectin Receptor Beta, Human 158
MADCA_HUMAN Q13477 CHEMBL4467 Mucosal Addressin Cell Adhesion Molecule-1, Human 44
ITB1_RAT P49134 CHEMBL2989 Fibronectin Receptor Beta, Rat 22
ITAV_HUMAN P06756 CHEMBL3660 Vitronectin Receptor Alpha, Human 1