| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 32 | 5 | 4 | 6 |
| Binding ≤ 1μM | 23 | 3 | 3 | 5 |
| Functional ≤ 10μM | 53 | 3 | 4 | 4 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_198969 | Activation of gene expression by SREBF (SREBP) | Mus musculus |
| REACT_198620 | BMAL1:CLOCK,NPAS2 activates circadian gene expression | Mus musculus |
| REACT_115781 | Bmal1:Clock,Npas2 activates circadian gene expression | Mus musculus |
| REACT_241925 | Circadian Clock | Mus musculus |
| REACT_234105 | Nuclear Receptor transcription pathway | Mus musculus |
| REACT_198602 | PPARA activates gene expression | Mus musculus |
| REACT_257219 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alp | Mus musculus |
| REACT_198352 | REV-ERBA represses gene expression | Mus musculus |
| REACT_198351 | RORA activates circadian gene expression | Mus musculus |
| REACT_205251 | Transcriptional activation of mitochondrial biogenesis | Mus musculus |
| REACT_252217 | Transcriptional regulation of white adipocyte differentiation | Mus musculus |
| REACT_196516 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | Mus musculus |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PPARD_MOUSE | P35396 | CHEMBL2458 | Peroxisome Proliferator-activated Receptor Delta, Mouse | 22 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| PPARA_CANFA | Q95N78 | CHEMBL2847 | Peroxisome Proliferator-activated Receptor Alpha, Canine | 35 | 0 | 0 | 0 |
| PPARA_HUMAN | Q07869 | CHEMBL239 | Peroxisome Proliferator-activated Receptor Alpha, Human | 1,414 | 22 | 16 | 24 |
| PPARA_RAT | P37230 | CHEMBL2129 | Peroxisome Proliferator-activated Receptor Alpha, Rat | 4 | 1 | 1 | 1 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| PPARA-1-E | Peroxisome Proliferator-activated Receptor Alpha (cluster #1 Of 3), Eukaryotic | 1,437 | 20 | 16 | 26 |
| PPARA-2-E | Peroxisome Proliferator-activated Receptor Alpha (cluster #2 Of 3), Eukaryotic | 12 | 2 | 2 | 0 |
| PPARA-3-E | Peroxisome Proliferator-activated Receptor Alpha (cluster #3 Of 3), Eukaryotic | 2 | 1 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| PPARA_HUMAN | Q07869 | CHEMBL239 | Peroxisome Proliferator-activated Receptor Alpha, Human | 78 |
| PPARG_HUMAN | P37231 | CHEMBL235 | Peroxisome Proliferator-activated Receptor Gamma, Human | 53 |
| PPARG_MOUSE | P37238 | CHEMBL2459 | Peroxisome Proliferator-activated Receptor Gamma, Mouse | 32 |
| PPARD_HUMAN | Q03181 | CHEMBL3979 | Peroxisome Proliferator-activated Receptor Delta, Human | 24 |
| PPARD_MOUSE | P35396 | CHEMBL2458 | Peroxisome Proliferator-activated Receptor Delta, Mouse | 22 |
| PPARA_CANFA | Q95N78 | CHEMBL2847 | Peroxisome Proliferator-activated Receptor Alpha, Canine | 3 |
| PPARA_RAT | P37230 | CHEMBL2129 | Peroxisome Proliferator-activated Receptor Alpha, Rat | 3 |
| Q7TNH1_MESAU | Q7TNH1 | CHEMBL1075150 | Peroxisome Proliferator Activated Receptor Alpha, Mesau | 1 |
| Z80006 | Z80006 | CHEMBL614510 | 3T3-L1 (Fibroblast Cells) | 1 |
