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S1PR3_HUMAN - Sphingosine 1-phosphate Receptor Edg-3, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Sphingosine 1-phosphate Receptor Edg-3, Human (317 Compounds)

Swissprot:
S1PR3_HUMAN
Stitch:
S1PR3_HUMAN
UniProt:
Q99500
ChEMBL:
CHEMBL3892
Reactome:
REACT_19231
REACT_18365
PDB:
S1PR3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 317 5 4 1
Binding ≤ 1μM 250 5 4 1
Functional ≤ 10μM 99 3 1 0

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_18365 Lysosphingolipid and LPA receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 29
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 400
S1PR2_HUMAN O95136 CHEMBL2955 Sphingosine 1-phosphate Receptor Edg-5, Human 112
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 177
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 173

Lysosphingolipid and LPA receptors

Uniprot Swissprot Chembl Description Number Shared
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 29
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 400
S1PR2_HUMAN O95136 CHEMBL2955 Sphingosine 1-phosphate Receptor Edg-5, Human 112
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 177
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 173
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 487 13 7 2
S1PR2_HUMAN O95136 CHEMBL2955 Sphingosine 1-phosphate Receptor Edg-5, Human 116 4 2 0
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 206 5 4 0
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 207 8 6 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
S1PR3-1-E Sphingosine 1-phosphate Receptor Edg-3 (cluster #1 Of 3), Eukaryotic 179 0 0 0
S1PR3-2-E Sphingosine 1-phosphate Receptor Edg-3 (cluster #2 Of 3), Eukaryotic 80 0 0 2
S1PR3-3-E Sphingosine 1-phosphate Receptor Edg-3 (cluster #3 Of 3), Eukaryotic 68 10 7 0
Uniprot Swissprot Chembl Description Number Shared
S1PR1_HUMAN P21453 CHEMBL4333 Sphingosine 1-phosphate Receptor Edg-1, Human 386
S1PR4_HUMAN O95977 CHEMBL3230 Sphingosine 1-phosphate Receptor Edg-6, Human 175
S1PR5_HUMAN Q9H228 CHEMBL2274 Sphingosine 1-phosphate Receptor Edg-8, Human 172
S1PR2_HUMAN O95136 CHEMBL2955 Sphingosine 1-phosphate Receptor Edg-5, Human 112
LPAR2_HUMAN Q9HBW0 CHEMBL3724 Lysophosphatidic Acid Receptor Edg-4, Human 29
SPHK1_HUMAN Q9NYA1 CHEMBL4394 Sphingosine Kinase 1, Human 1

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