UCSF

Acetyl-CoA Carboxylase 2, Human (452 Compounds)

Swissprot:
ACACB_HUMAN
Stitch:
ACACB_HUMAN
UniProt:
O00763
ChEMBL:
CHEMBL4829
Reactome:
REACT_147904
REACT_11153
REACT_2122
REACT_169312
REACT_11082
PDB:
2DN8 (DOCK)
2HJW (DOCK)
2KCC (DOCK)
3FF6 (DOCK)
3GID (DOCK)
3GLK (DOCK)
3JRW (DOCK)
3JRX (DOCK)
ACACB

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 452 1 0 0
Binding ≤ 1μM 401 0 0 0

Reactome Network (5)

Reactome ID Description Species
REACT_147904 Activation of gene expression by SREBF (SREBP) Homo sapiens
REACT_11153 Biotin transport and metabolism Homo sapiens
REACT_2122 ChREBP activates metabolic gene expression Homo sapiens
REACT_169312 Defective HLCS causes multiple carboxylase deficiency Homo sapiens
REACT_11082 Import of palmitoyl-CoA into the mitochondrial matrix Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 272

Biotin transport and metabolism

Uniprot Swissprot Chembl Description Number Shared
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 272

ChREBP activates metabolic gene expression

Uniprot Swissprot Chembl Description Number Shared
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 272

Defective HLCS causes multiple carboxylase deficiency

Uniprot Swissprot Chembl Description Number Shared
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 272

Import of palmitoyl-CoA into the mitochondrial matrix

Uniprot Swissprot Chembl Description Number Shared
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 272

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ACACA_HUMAN Q13085 CHEMBL3351 Acetyl-CoA Carboxylase 1, Human 272
ACACA_RAT P11497 CHEMBL2397 Acetyl-CoA Carboxylase 1, Rat 56
Q1HEC0_RAT Q1HEC0 CHEMBL5125 Acetyl-Coenzyme A Carboxylase 2, Rat 5

Most Common Rings