| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 57 | 11 | 1 | 1 |
| Binding ≤ 1μM | 37 | 1 | 1 | 1 |
| Functional ≤ 10μM | 3 | 0 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_206751 | Synthesis of 5-eicosatetraenoic acids | Mus musculus |
| REACT_215561 | Synthesis of Leukotrienes (LT) and Eoxins (EX) | Mus musculus |
| REACT_196544 | Synthesis of Lipoxins (LX) | Mus musculus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| LOX5_HUMAN | P09917 | CHEMBL215 | Arachidonate 5-lipoxygenase, Human | 952 | 85 | 36 | 16 |
| LOX5_RAT | P12527 | CHEMBL312 | Arachidonate 5-lipoxygenase, Rat | 1,236 | 82 | 35 | 22 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| LOX12_MOUSE | P39655 | CHEMBL3225 | Arachidonate 12-lipoxygenase, Mouse | 3 | 0 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| LOX5-1-E | Arachidonate 5-lipoxygenase (cluster #1 Of 6), Eukaryotic | 1,382 | 99 | 38 | 23 |
| LOX5-2-E | Arachidonate 5-lipoxygenase (cluster #2 Of 6), Eukaryotic | 64 | 8 | 6 | 2 |
| LOX5-3-E | Arachidonate 5-lipoxygenase (cluster #3 Of 6), Eukaryotic | 17 | 1 | 0 | 0 |
| LOX5-4-E | Arachidonate 5-lipoxygenase (cluster #4 Of 6), Eukaryotic | 260 | 19 | 8 | 5 |
| LOX5-5-E | Arachidonate 5-lipoxygenase (cluster #5 Of 6), Eukaryotic | 119 | 11 | 4 | 0 |
| LOX5-6-E | Arachidonate 5-lipoxygenase (cluster #6 Of 6), Eukaryotic | 309 | 24 | 8 | 4 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| LOX5_HUMAN | P09917 | CHEMBL215 | Arachidonate 5-lipoxygenase, Human | 25 |
| LOX5_RAT | P12527 | CHEMBL312 | Arachidonate 5-lipoxygenase, Rat | 10 |
| PGH2_MOUSE | Q05769 | CHEMBL4321 | Cyclooxygenase-2, Mouse | 6 |
| PA24A_HUMAN | P47712 | CHEMBL3816 | Cytosolic Phospholipase A2, Human | 3 |
| Z100741 | Z100741 | CHEMBL614867 | MC9 (Mast Cells) | 3 |
| PGH1_RAT | Q63921 | CHEMBL4042 | Cyclooxygenase-1, Rat | 2 |
| PGH1_MOUSE | P22437 | CHEMBL2649 | Cyclooxygenase-1, Mouse | 1 |
| PGH2_RAT | P35355 | CHEMBL2977 | Cyclooxygenase-2, Rat | 1 |
| Z80156 | Z80156 | CHEMBL383 | HL-60 (Promyeloblast Leukemia Cells) | 1 |
