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ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (59)
Reactome (6)
Related By:
Pathway (14)
Organism (1)
Gene (7)
Org. Clust. (1)
ChEMBL (18)
Rings (0)

Phospholipase A2 Group V, Human (59 Compounds)

Swissprot:: PA2G5_HUMAN
Stitch:: PA2G5_HUMAN
UniProt:: P39877
ChEMBL:: CHEMBL4323
Reactome:: REACT_120829; REACT_121369; REACT_121324; REACT_120722; REACT_121384; REACT_120906
PDB:: 2GHN (DOCK); PLA2G5

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	59	1	1	1
Binding ≤ 1μM	53	1	1	1

Reactome ID	Description	Species
REACT_120829	Acyl chain remodelling of PC	Homo sapiens
REACT_121369	Acyl chain remodelling of PE	Homo sapiens
REACT_121324	Acyl chain remodelling of PG	Homo sapiens
REACT_120722	Acyl chain remodelling of PI	Homo sapiens
REACT_121384	Acyl chain remodelling of PS	Homo sapiens
REACT_120906	Synthesis of PA	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24

Acyl chain remodelling of PE

Uniprot	Swissprot	Chembl	Description	Number Shared
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24

Acyl chain remodelling of PG

Uniprot	Swissprot	Chembl	Description	Number Shared
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24

Acyl chain remodelling of PI

Uniprot	Swissprot	Chembl	Description	Number Shared
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24

Acyl chain remodelling of PS

Uniprot	Swissprot	Chembl	Description	Number Shared
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24

Synthesis of PA

Uniprot	Swissprot	Chembl	Description	Number Shared
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PA2G5_MOUSE	P97391	CHEMBL4167	Phospholipase A2 Group V, Mouse	17	1	1	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PA2G6_HUMAN	O60733	CHEMBL3213	Calcium-independent Phospholipase A2, Human	28	2	0	0
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	315	7	3	3
PA2GC_HUMAN	Q5R387	CHEMBL2097	Phospholipase A2 Group IIC, Human	17	0	0	0
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	33	2	2	1
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	30	2	2	1
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	25	2	2	1
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	49	1	1	1

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
PA2G5-1-E	Phospholipase A2 Group V (cluster #1 Of 2), Eukaryotic	57	1	1	1
PA2G5-2-E	Phospholipase A2 Group V (cluster #2 Of 2), Eukaryotic	2	0	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
PA2GA_HUMAN	P14555	CHEMBL3474	Phospholipase A2 Group IIA, Human	59
PA21B_HUMAN	P04054	CHEMBL4426	Phospholipase A2 Group 1B, Human	48
PA24A_HUMAN	P47712	CHEMBL3816	Cytosolic Phospholipase A2, Human	30
PA2GX_HUMAN	O15496	CHEMBL4342	Group X Secretory Phospholipase A2, Human	24
PA2G5_MOUSE	P97391	CHEMBL4167	Phospholipase A2 Group V, Mouse	17
PA2GA_MOUSE	P31482	CHEMBL5761	Phospholipase A2, Membrane Associated, Mouse	14
PA21B_MOUSE	Q9Z0Y2	CHEMBL4378	Phospholipase A2 Group 1B, Mouse	10
PA2GE_HUMAN	Q9NZK7	CHEMBL2154	Group IIE Secretory Phospholipase A2, Human	10
PA2GE_MOUSE	Q9QUL3	CHEMBL4201	Group IIE Secretory Phospholipase A2, Mouse	10
PA2GX_MOUSE	Q9QXX3	CHEMBL4200	Group X Secretory Phospholipase A2, Mouse	10
PA21B_PIG	P00592	CHEMBL4715	Phospholipase A2 Group 1B, Pig	7
PA2GA_RAT	P14423	CHEMBL3686	Phospholipase A2 Group IIA, Rat	6
PA2GD_HUMAN	Q9UNK4	CHEMBL4281	Group IID Secretory Phospholipase A2, Human	6
PA2GF_HUMAN	Q9BZM2	CHEMBL4278	Group IIF Secretory Phospholipase A2, Human	6
PAFA_HUMAN	Q13093	CHEMBL3514	LDL-associated Phospholipase A2, Human	6
PA2GA_RABIT	P14422	CHEMBL5481	Phospholipase A2, Membrane Associated, Rabit	5
PA2GD_MOUSE	Q9WVF6	CHEMBL5537	Group IID Secretory Phospholipase A2, Mouse	4
PA2GF_MOUSE	Q9QZT4	CHEMBL5361	Group IIF Secretory Phospholipase A2, Mouse	3

Synonyms
Compounds (59)
Related By:
Pathway (14)
Organism (1)
Gene (7)
ChEMBL (18)
Org. Clust. (1)
Rings (0)