| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 27th, 2005 | 20 | Yes |
1-Methyl-5-phenyl-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-
439-14-5; D00293; Diastat (TN); Diazepam (JP16/USP/INN); Valium (TN)
5-24-04-00300 (Beilstein Handbook Reference)
7-Chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepine
7-Chloro-1-methyl-5-3H-1,4-benzodiazepin-2(1H)-one
7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
7-Chloro-1-methyl-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
7-Chloro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2(1H)-one
7-chloro-1-methyl-5-phenyl-3H-1,4-benzodiazepin-2-one
CPD000058398; Diazepam; SAM001246536
CPD000058398; SAM001246536; diazepam
Methyldiazepinone (pharmaceutical)
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.74 | 6.91 | -8.26 | 0 | 3 | 0 | 33 | 284.746 | 1 | ↓ |
| Lo Low (pH 4.5-6) | 2.74 | 7.78 | -30.37 | 1 | 3 | 1 | 34 | 285.754 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 1.22e-02 g/l | DrugBank-Street Drugs |
| Purity | 97% | APIChem |
| UniProt Database Links | ACBD5_BOVIN; ACBP1_CAEEL; ACBP_ANAPL; ACBP_BOVIN; ACBP_CANFA; ACBP_CHICK; ACBP_DICDI; ACBP_DROME; ACBP_HUMAN; ACBP_MANSE; ACBP_MOUSE; ACBP_PELRI; ACBP_PIG; ACBP_RABIT; ACBP_RAT; CP2CJ_HUMAN; DBIL5_BOVIN; DBIL5_MOUSE; DBIL5_RAT; ECI2_HUMAN; GBRA4_HUMAN; PD | ChEBI |
| Patent Database Links | EP0769300; EP1078637; EP1262184; EP1273575; EP1438962; EP1514877; EP1543841; EP1600169; EP1629835; EP1661557; EP1698329; EP1705244; EP1731142; EP1749516; EP1749525; EP1759713; EP1839657; EP1867641; EP1884243; EP1925314; EP1990639; GB2014849; US2002147336 | ChEBI |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : Sequoia Research Products Ltd.; NCC_SUPPLIER_STRUCTURE_ID : SRP02375d; NCC_CONTROLLED_SUBSTANCE : DEA SCHEDULE 4 | NIH Clinical Collection via PubChem |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: Sequoia Research Products Ltd.; SUPPLIER_STRUCTURE_ID: SRP02375d | NIH Clinical Collection via PubChem |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| A2AMW3-2-E | GABA Receptor Epsilon Subunit (cluster #2 Of 2), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| AA3R-3-E | Adenosine Receptor A3 (cluster #3 Of 6), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| FABPL-2-E | Fatty Acid-binding Protein, Liver (cluster #2 Of 4), Eukaryotic | Eukaryotes | 531 | 0.44 | Binding ≤ 10μM |
| GBRA1-1-E | GABA Receptor Alpha-1 Subunit (cluster #1 Of 8), Eukaryotic | Eukaryotes | 5600 | 0.37 | Binding ≤ 10μM |
| GBRA2-1-E | GABA Receptor Alpha-2 Subunit (cluster #1 Of 8), Eukaryotic | Eukaryotes | 8 | 0.57 | Binding ≤ 10μM |
| GBRA3-1-E | GABA Receptor Alpha-3 Subunit (cluster #1 Of 8), Eukaryotic | Eukaryotes | 8 | 0.57 | Binding ≤ 10μM |
| GBRA4-1-E | GABA Receptor Alpha-4 Subunit (cluster #1 Of 7), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRA5-6-E | GABA Receptor Alpha-5 Subunit (cluster #6 Of 8), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRA6-2-E | GABA Receptor Alpha-6 Subunit (cluster #2 Of 8), Eukaryotic | Eukaryotes | 8 | 0.57 | Binding ≤ 10μM |
| GBRB1-1-E | GABA Receptor Beta-1 Subunit (cluster #1 Of 6), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRB2-1-E | GABA Receptor Beta-2 Subunit (cluster #1 Of 7), Eukaryotic | Eukaryotes | 98 | 0.49 | Binding ≤ 10μM |
| GBRB3-1-E | GABA Receptor Beta-3 Subunit (cluster #1 Of 6), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRD-1-E | GABA Receptor Delta Subunit (cluster #1 Of 5), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRE-1-E | GABA Receptor Epsilon Subunit (cluster #1 Of 5), Eukaryotic | Eukaryotes | 5 | 0.58 | Binding ≤ 10μM |
| GBRG1-1-E | GABA Receptor Gamma-1 Subunit (cluster #1 Of 7), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRG2-1-E | GABA Receptor Gamma-2 Subunit (cluster #1 Of 7), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRG3-2-E | GABA Receptor Gamma-3 Subunit (cluster #2 Of 7), Eukaryotic | Eukaryotes | 8 | 0.57 | Binding ≤ 10μM |
| GBRP-1-E | GABA Receptor Pi Subunit (cluster #1 Of 6), Eukaryotic | Eukaryotes | 12 | 0.55 | Binding ≤ 10μM |
| GBRR1-1-E | GABA Receptor Rho-1 Subunit (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5 | 0.58 | Binding ≤ 10μM |
| GBRT-2-E | GABA Receptor Theta Subunit (cluster #2 Of 5), Eukaryotic | Eukaryotes | 8 | 0.57 | Binding ≤ 10μM |
| Q91ZM7-1-E | GABA Receptor Theta Subunit (cluster #1 Of 3), Eukaryotic | Eukaryotes | 5 | 0.58 | Binding ≤ 10μM |
| TSPO-1-E | Peripheral-type Benzodiazepine Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 574 | 0.44 | Binding ≤ 10μM |
| GBRA1-4-E | GABA Receptor Alpha-1 Subunit (cluster #4 Of 5), Eukaryotic | Eukaryotes | 2 | 0.61 | Functional ≤ 10μM |
| GBRA2-1-E | GABA Receptor Alpha-2 Subunit (cluster #1 Of 4), Eukaryotic | Eukaryotes | 2 | 0.61 | Functional ≤ 10μM |
| GBRG1-2-E | GABA Receptor Gamma-1 Subunit (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5 | 0.58 | Functional ≤ 10μM |
| Z104301-1-O | GABA-A Receptor; Anion Channel (cluster #1 Of 8), Other | Other | 5 | 0.58 | Binding ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 5 | 0.58 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AA3R_HUMAN | P33765 | Adenosine A3 Receptor, Human | 12 | 0.55 | Binding ≤ 1μM |
| FABPL_RAT | P02692 | Fatty Acid-binding Protein, Liver, Rat | 531 | 0.44 | Binding ≤ 1μM |
| GBRA1_HUMAN | P14867 | GABA Receptor Alpha-1 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRA1_RAT | P62813 | GABA Receptor Alpha-1 Subunit, Rat | 11 | 0.56 | Binding ≤ 1μM |
| GBRA1_MOUSE | P62812 | GABA Receptor Alpha-1 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRA1_BOVIN | P08219 | GABA Receptor Alpha-1 Subunit, Bovin | 10 | 0.56 | Binding ≤ 1μM |
| GBRA2_MOUSE | P26048 | GABA Receptor Alpha-2 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRA2_HUMAN | P47869 | GABA Receptor Alpha-2 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRA2_RAT | P23576 | GABA Receptor Alpha-2 Subunit, Rat | 15 | 0.55 | Binding ≤ 1μM |
| GBRA2_BOVIN | P10063 | GABA Receptor Alpha-2 Subunit, Bovin | 10 | 0.56 | Binding ≤ 1μM |
| GBRA3_HUMAN | P34903 | GABA Receptor Alpha-3 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRA3_BOVIN | P10064 | GABA Receptor Alpha-3 Subunit, Bovin | 10 | 0.56 | Binding ≤ 1μM |
| GBRA3_RAT | P20236 | GABA Receptor Alpha-3 Subunit, Rat | 13.9 | 0.55 | Binding ≤ 1μM |
| GBRA3_MOUSE | P26049 | GABA Receptor Alpha-3 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRA4_MOUSE | Q9D6F4 | GABA Receptor Alpha-4 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRA4_BOVIN | P20237 | GABA Receptor Alpha-4 Subunit, Bovin | 10 | 0.56 | Binding ≤ 1μM |
| GBRA4_RAT | P28471 | GABA Receptor Alpha-4 Subunit, Rat | 23 | 0.53 | Binding ≤ 1μM |
| GBRA4_HUMAN | P48169 | GABA Receptor Alpha-4 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRA5_HUMAN | P31644 | GABA Receptor Alpha-5 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRA5_RAT | P19969 | GABA Receptor Alpha-5 Subunit, Rat | 11 | 0.56 | Binding ≤ 1μM |
| GBRA5_MOUSE | Q8BHJ7 | GABA Receptor Alpha-5 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRA6_HUMAN | Q16445 | GABA Receptor Alpha-6 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRA6_MOUSE | P16305 | GABA Receptor Alpha-6 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRA6_RAT | P30191 | GABA Receptor Alpha-6 Subunit, Rat | 2.1 | 0.61 | Binding ≤ 1μM |
| GBRB1_HUMAN | P18505 | GABA Receptor Beta-1 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRB1_RAT | P15431 | GABA Receptor Beta-1 Subunit, Rat | 4.9 | 0.58 | Binding ≤ 1μM |
| GBRB1_BOVIN | P08220 | GABA Receptor Beta-1 Subunit, Bovin | 10 | 0.56 | Binding ≤ 1μM |
| GBRB1_MOUSE | P50571 | GABA Receptor Beta-1 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRB2_HUMAN | P47870 | GABA Receptor Beta-2 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRB2_RAT | P63138 | GABA Receptor Beta-2 Subunit, Rat | 11 | 0.56 | Binding ≤ 1μM |
| GBRB3_MOUSE | P63080 | GABA Receptor Beta-3 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRB3_RAT | P63079 | GABA Receptor Beta-3 Subunit, Rat | 11 | 0.56 | Binding ≤ 1μM |
| GBRB3_HUMAN | P28472 | GABA Receptor Beta-3 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRD_RAT | P18506 | GABA Receptor Delta Subunit, Rat | 4.9 | 0.58 | Binding ≤ 1μM |
| GBRD_HUMAN | O14764 | GABA Receptor Delta Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRD_MOUSE | P22933 | GABA Receptor Delta Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRE_HUMAN | P78334 | GABA Receptor Epsilon Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| A2AMW3_MOUSE | A2AMW3 | GABA Receptor Epsilon Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRE_RAT | Q9ES14 | GABA Receptor Epsilon Subunit, Rat | 4.9 | 0.58 | Binding ≤ 1μM |
| GBRG1_RAT | P23574 | GABA Receptor Gamma-1 Subunit, Rat | 4.9 | 0.58 | Binding ≤ 1μM |
| GBRG1_MOUSE | Q9R0Y8 | GABA Receptor Gamma-1 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRG1_HUMAN | Q8N1C3 | GABA Receptor Gamma-1 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRG2_MOUSE | P22723 | GABA Receptor Gamma-2 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRG2_BOVIN | P22300 | GABA Receptor Gamma-2 Subunit, Bovin | 10 | 0.56 | Binding ≤ 1μM |
| GBRG2_RAT | P18508 | GABA Receptor Gamma-2 Subunit, Rat | 11 | 0.56 | Binding ≤ 1μM |
| GBRG2_HUMAN | P18507 | GABA Receptor Gamma-2 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRG3_RAT | P28473 | GABA Receptor Gamma-3 Subunit, Rat | 11 | 0.56 | Binding ≤ 1μM |
| GBRG3_HUMAN | Q99928 | GABA Receptor Gamma-3 Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRG3_MOUSE | P27681 | GABA Receptor Gamma-3 Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRP_HUMAN | O00591 | GABA Receptor Pi Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRP_MOUSE | Q8QZW7 | GABA Receptor Pi Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| GBRR1_RAT | P50572 | GABA Receptor Rho-1 Subunit, Rat | 4.9 | 0.58 | Binding ≤ 1μM |
| GBRT_HUMAN | Q9UN88 | GABA Receptor Theta Subunit, Human | 10 | 0.56 | Binding ≤ 1μM |
| GBRT_MOUSE | Q9JLF1 | GABA Receptor Theta Subunit, Mouse | 12 | 0.55 | Binding ≤ 1μM |
| Q91ZM7_RAT | Q91ZM7 | GABA Receptor Theta Subunit, Rat | 4.9 | 0.58 | Binding ≤ 1μM |
| Z104301 | Z104301 | GABA-A Receptor; Anion Channel | 10.5 | 0.56 | Binding ≤ 1μM |
| TSPO_RAT | P16257 | Peripheral-type Benzodiazepine Receptor, Rat | 213 | 0.47 | Binding ≤ 1μM |
| AA3R_HUMAN | P33765 | Adenosine A3 Receptor, Human | 12 | 0.55 | Binding ≤ 10μM |
| FABPL_RAT | P02692 | Fatty Acid-binding Protein, Liver, Rat | 531 | 0.44 | Binding ≤ 10μM |
| GBRA1_BOVIN | P08219 | GABA Receptor Alpha-1 Subunit, Bovin | 10 | 0.56 | Binding ≤ 10μM |
| GBRA1_HUMAN | P14867 | GABA Receptor Alpha-1 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRA1_RAT | P62813 | GABA Receptor Alpha-1 Subunit, Rat | 11 | 0.56 | Binding ≤ 10μM |
| GBRA1_MOUSE | P62812 | GABA Receptor Alpha-1 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRA2_BOVIN | P10063 | GABA Receptor Alpha-2 Subunit, Bovin | 10 | 0.56 | Binding ≤ 10μM |
| GBRA2_MOUSE | P26048 | GABA Receptor Alpha-2 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRA2_HUMAN | P47869 | GABA Receptor Alpha-2 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRA2_RAT | P23576 | GABA Receptor Alpha-2 Subunit, Rat | 15 | 0.55 | Binding ≤ 10μM |
| GBRA3_RAT | P20236 | GABA Receptor Alpha-3 Subunit, Rat | 13.9 | 0.55 | Binding ≤ 10μM |
| GBRA3_MOUSE | P26049 | GABA Receptor Alpha-3 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRA3_HUMAN | P34903 | GABA Receptor Alpha-3 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRA3_BOVIN | P10064 | GABA Receptor Alpha-3 Subunit, Bovin | 10 | 0.56 | Binding ≤ 10μM |
| GBRA4_RAT | P28471 | GABA Receptor Alpha-4 Subunit, Rat | 23 | 0.53 | Binding ≤ 10μM |
| GBRA4_HUMAN | P48169 | GABA Receptor Alpha-4 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRA4_MOUSE | Q9D6F4 | GABA Receptor Alpha-4 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRA4_BOVIN | P20237 | GABA Receptor Alpha-4 Subunit, Bovin | 10 | 0.56 | Binding ≤ 10μM |
| GBRA5_RAT | P19969 | GABA Receptor Alpha-5 Subunit, Rat | 11 | 0.56 | Binding ≤ 10μM |
| GBRA5_MOUSE | Q8BHJ7 | GABA Receptor Alpha-5 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRA5_HUMAN | P31644 | GABA Receptor Alpha-5 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRA6_HUMAN | Q16445 | GABA Receptor Alpha-6 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRA6_MOUSE | P16305 | GABA Receptor Alpha-6 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRA6_RAT | P30191 | GABA Receptor Alpha-6 Subunit, Rat | 2.1 | 0.61 | Binding ≤ 10μM |
| GBRB1_BOVIN | P08220 | GABA Receptor Beta-1 Subunit, Bovin | 10 | 0.56 | Binding ≤ 10μM |
| GBRB1_MOUSE | P50571 | GABA Receptor Beta-1 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRB1_HUMAN | P18505 | GABA Receptor Beta-1 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRB1_RAT | P15431 | GABA Receptor Beta-1 Subunit, Rat | 4.9 | 0.58 | Binding ≤ 10μM |
| GBRB2_HUMAN | P47870 | GABA Receptor Beta-2 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRB2_RAT | P63138 | GABA Receptor Beta-2 Subunit, Rat | 11 | 0.56 | Binding ≤ 10μM |
| GBRB3_HUMAN | P28472 | GABA Receptor Beta-3 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRB3_MOUSE | P63080 | GABA Receptor Beta-3 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRB3_RAT | P63079 | GABA Receptor Beta-3 Subunit, Rat | 11 | 0.56 | Binding ≤ 10μM |
| GBRD_RAT | P18506 | GABA Receptor Delta Subunit, Rat | 4.9 | 0.58 | Binding ≤ 10μM |
| GBRD_HUMAN | O14764 | GABA Receptor Delta Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRD_MOUSE | P22933 | GABA Receptor Delta Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRE_HUMAN | P78334 | GABA Receptor Epsilon Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| A2AMW3_MOUSE | A2AMW3 | GABA Receptor Epsilon Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRE_RAT | Q9ES14 | GABA Receptor Epsilon Subunit, Rat | 4.9 | 0.58 | Binding ≤ 10μM |
| GBRG1_HUMAN | Q8N1C3 | GABA Receptor Gamma-1 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRG1_RAT | P23574 | GABA Receptor Gamma-1 Subunit, Rat | 4.9 | 0.58 | Binding ≤ 10μM |
| GBRG1_MOUSE | Q9R0Y8 | GABA Receptor Gamma-1 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRG2_RAT | P18508 | GABA Receptor Gamma-2 Subunit, Rat | 11 | 0.56 | Binding ≤ 10μM |
| GBRG2_HUMAN | P18507 | GABA Receptor Gamma-2 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRG2_MOUSE | P22723 | GABA Receptor Gamma-2 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRG2_BOVIN | P22300 | GABA Receptor Gamma-2 Subunit, Bovin | 10 | 0.56 | Binding ≤ 10μM |
| GBRG3_MOUSE | P27681 | GABA Receptor Gamma-3 Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRG3_RAT | P28473 | GABA Receptor Gamma-3 Subunit, Rat | 11 | 0.56 | Binding ≤ 10μM |
| GBRG3_HUMAN | Q99928 | GABA Receptor Gamma-3 Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRP_MOUSE | Q8QZW7 | GABA Receptor Pi Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| GBRP_HUMAN | O00591 | GABA Receptor Pi Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRR1_RAT | P50572 | GABA Receptor Rho-1 Subunit, Rat | 4.9 | 0.58 | Binding ≤ 10μM |
| Q91ZM7_RAT | Q91ZM7 | GABA Receptor Theta Subunit, Rat | 4.9 | 0.58 | Binding ≤ 10μM |
| GBRT_HUMAN | Q9UN88 | GABA Receptor Theta Subunit, Human | 10 | 0.56 | Binding ≤ 10μM |
| GBRT_MOUSE | Q9JLF1 | GABA Receptor Theta Subunit, Mouse | 12 | 0.55 | Binding ≤ 10μM |
| Z104301 | Z104301 | GABA-A Receptor; Anion Channel | 10.5 | 0.56 | Binding ≤ 10μM |
| TSPO_RAT | P16257 | Peripheral-type Benzodiazepine Receptor, Rat | 213 | 0.47 | Binding ≤ 10μM |
| GBRA1_RAT | P62813 | GABA Receptor Alpha-1 Subunit, Rat | 1.8 | 0.61 | Functional ≤ 10μM |
| GBRA2_RAT | P23576 | GABA Receptor Alpha-2 Subunit, Rat | 1.8 | 0.61 | Functional ≤ 10μM |
| GBRG1_RAT | P23574 | GABA Receptor Gamma-1 Subunit, Rat | 1.8 | 0.61 | Functional ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 5 | 0.58 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Adenosine P1 receptors | |
| G alpha (i) signalling events | |
| GABA A receptor activation | |
| Ligand-gated ion channel transport | |
| PPARA activates gene expression | |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alp |
