| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 29 | 1 | 1 | 1 |
| Binding ≤ 1μM | 15 | 1 | 1 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_118682 | Activation of Matrix Metalloproteinases | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| MMP10_HUMAN | P09238 | CHEMBL4270 | Matrix Metalloproteinase 10, Human | 1 |
| MMP11_HUMAN | P24347 | CHEMBL2867 | Matrix Metalloproteinase 11, Human | 1 |
| MMP13_HUMAN | P45452 | CHEMBL280 | Matrix Metalloproteinase 13, Human | 19 |
| MMP14_HUMAN | P50281 | CHEMBL3869 | Matrix Metalloproteinase 14, Human | 1 |
| MMP15_HUMAN | P51511 | CHEMBL2963 | Matrix Metalloproteinase 15, Human | 1 |
| MMP16_HUMAN | P51512 | CHEMBL2200 | Matrix Metalloproteinase 16, Human | 1 |
| MMP1_HUMAN | P03956 | CHEMBL332 | Matrix Metalloproteinase-1, Human | 1 |
| MMP2_HUMAN | P08253 | CHEMBL333 | Matrix Metalloproteinase-2, Human | 11 |
| MMP3_HUMAN | P08254 | CHEMBL283 | Matrix Metalloproteinase 3, Human | 29 |
| MMP7_HUMAN | P09237 | CHEMBL4073 | Matrix Metalloproteinase 7, Human | 1 |
| MMP8_HUMAN | P22894 | CHEMBL4588 | Matrix Metalloproteinase 8, Human | 1 |
| MMP9_HUMAN | P14780 | CHEMBL321 | Matrix Metalloproteinase 9, Human | 1 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| MMP10_HUMAN | P09238 | CHEMBL4270 | Matrix Metalloproteinase 10, Human | 82 | 1 | 1 | 1 |
| MMP11_HUMAN | P24347 | CHEMBL2867 | Matrix Metalloproteinase 11, Human | 71 | 1 | 1 | 1 |
| MMP12_HUMAN | P39900 | CHEMBL4393 | Matrix Metalloproteinase 12, Human | 289 | 8 | 4 | 5 |
| MMP13_HUMAN | P45452 | CHEMBL280 | Matrix Metalloproteinase 13, Human | 2,513 | 43 | 6 | 37 |
| MMP14_HUMAN | P50281 | CHEMBL3869 | Matrix Metalloproteinase 14, Human | 507 | 9 | 8 | 14 |
| MMP15_HUMAN | P51511 | CHEMBL2963 | Matrix Metalloproteinase 15, Human | 30 | 1 | 1 | 3 |
| MMP16_HUMAN | P51512 | CHEMBL2200 | Matrix Metalloproteinase 16, Human | 61 | 3 | 1 | 4 |
| MMP1_HUMAN | P03956 | CHEMBL332 | Matrix Metalloproteinase-1, Human | 2,665 | 22 | 9 | 44 |
| MMP25_HUMAN | Q9NPA2 | CHEMBL1795103 | Matrix Metalloproteinase-25, Human | 8 | 0 | 0 | 1 |
| MMP26_HUMAN | Q9NRE1 | CHEMBL4707 | Matrix Metalloproteinase 26, Human | 23 | 1 | 1 | 2 |
| MMP2_HUMAN | P08253 | CHEMBL333 | Matrix Metalloproteinase-2, Human | 2,765 | 37 | 17 | 44 |
| MMP3_HUMAN | P08254 | CHEMBL283 | Matrix Metalloproteinase 3, Human | 2,212 | 22 | 9 | 40 |
| MMP7_HUMAN | P09237 | CHEMBL4073 | Matrix Metalloproteinase 7, Human | 467 | 10 | 4 | 22 |
| MMP8_HUMAN | P22894 | CHEMBL4588 | Matrix Metalloproteinase 8, Human | 980 | 16 | 6 | 25 |
| MMP9_HUMAN | P14780 | CHEMBL321 | Matrix Metalloproteinase 9, Human | 2,243 | 31 | 11 | 34 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| ADA17_HUMAN | P78536 | CHEMBL3706 | ADAM17, Human | 29 |
| MMP3_HUMAN | P08254 | CHEMBL283 | Matrix Metalloproteinase 3, Human | 29 |
| MMP13_HUMAN | P45452 | CHEMBL280 | Matrix Metalloproteinase 13, Human | 19 |
| MMP2_HUMAN | P08253 | CHEMBL333 | Matrix Metalloproteinase-2, Human | 11 |
| ADA10_HUMAN | O14672 | CHEMBL5028 | ADAM10, Human | 1 |
| ADA12_HUMAN | O43184 | CHEMBL5030 | ADAM12, Human | 1 |
| ADAM9_HUMAN | Q13443 | CHEMBL5982 | ADAM9, Human | 1 |
| MMP10_HUMAN | P09238 | CHEMBL4270 | Matrix Metalloproteinase 10, Human | 1 |
| MMP11_HUMAN | P24347 | CHEMBL2867 | Matrix Metalloproteinase 11, Human | 1 |
| MMP12_HUMAN | P39900 | CHEMBL4393 | Matrix Metalloproteinase 12, Human | 1 |
| MMP14_HUMAN | P50281 | CHEMBL3869 | Matrix Metalloproteinase 14, Human | 1 |
| MMP15_HUMAN | P51511 | CHEMBL2963 | Matrix Metalloproteinase 15, Human | 1 |
| MMP16_HUMAN | P51512 | CHEMBL2200 | Matrix Metalloproteinase 16, Human | 1 |
| MMP1_HUMAN | P03956 | CHEMBL332 | Matrix Metalloproteinase-1, Human | 1 |
| MMP26_HUMAN | Q9NRE1 | CHEMBL4707 | Matrix Metalloproteinase 26, Human | 1 |
| MMP7_HUMAN | P09237 | CHEMBL4073 | Matrix Metalloproteinase 7, Human | 1 |
| MMP8_HUMAN | P22894 | CHEMBL4588 | Matrix Metalloproteinase 8, Human | 1 |
| MMP9_HUMAN | P14780 | CHEMBL321 | Matrix Metalloproteinase 9, Human | 1 |