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ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (2)
Reactome (9)
Related By:
Pathway (9)
Organism (2)
Gene (7)
Org. Clust. (1)
ChEMBL (17)
Rings (0)

Adenylate Cyclase Type IV, Mouse (2 Compounds)

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	2	0	0	0
Binding ≤ 1μM	2	0	0	0

Reactome ID	Description	Species
REACT_224974	Adenylate cyclase activating pathway	Mus musculus
REACT_222824	Adenylate cyclase inhibitory pathway	Mus musculus
REACT_250376	G alpha (i) signalling events	Mus musculus
REACT_242871	G alpha (s) signalling events	Mus musculus
REACT_258013	G alpha (z) signalling events	Mus musculus
REACT_210399	Glucagon signaling in metabolic regulation	Mus musculus
REACT_220108	PKA activation	Mus musculus
REACT_220758	PKA activation in glucagon signalling	Mus musculus
REACT_213947	Vasopressin regulates renal water homeostasis via Aquaporins	Mus musculus

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

Adenylate cyclase inhibitory pathway

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

G alpha (i) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

G alpha (s) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

G alpha (z) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

Glucagon signaling in metabolic regulation

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

PKA activation

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

PKA activation in glucagon signalling

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

Vasopressin regulates renal water homeostasis via Aquaporins

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ADCY4_HUMAN	Q8NFM4	CHEMBL2533	Adenylate Cyclase Type IV, Human	23	0	0	0
ADCY4_RAT	P26770	CHEMBL2879	Adenylate Cyclase Type IV, Rat	36	24	5	5

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2	0	0	0
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2	0	0	0
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2	0	0	0
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2	0	0	0
ADCY6_MOUSE	Q01341	CHEMBL3015	Adenylate Cyclase Type VI, Mouse	2	0	0	0
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2	0	0	0
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2	0	0	0

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
ADCY4-1-E	Adenylate Cyclase Type IV (cluster #1 Of 2), Eukaryotic	11	10	2	2
ADCY4-2-E	Adenylate Cyclase Type IV (cluster #2 Of 2), Eukaryotic	51	15	3	3

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	2
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_HUMAN	O60266	CHEMBL3164	Adenylate Cyclase Type III, Human	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_HUMAN	Q8NFM4	CHEMBL2533	Adenylate Cyclase Type IV, Human	2
ADCY5_HUMAN	O95622	CHEMBL3189	Adenylate Cyclase Type V, Human	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY6_HUMAN	O43306	CHEMBL3221	Adenylate Cyclase Type VI, Human	2
ADCY6_MOUSE	Q01341	CHEMBL3015	Adenylate Cyclase Type VI, Mouse	2
ADCY7_HUMAN	P51828	CHEMBL4922	Adenylate Cyclase Type VII, Human	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	2
ADCY8_MOUSE	P97490	CHEMBL2961	Adenylate Cyclase Type VIII, Mouse	2
ADCY9_HUMAN	O60503	CHEMBL2655	Adenylate Cyclase Type IX, Human	2
GLR_HUMAN	P47871	CHEMBL1985	Glucagon Receptor, Human	2

Synonyms
Compounds (2)
Related By:
Pathway (9)
Organism (2)
Gene (7)
ChEMBL (17)
Org. Clust. (1)
Rings (0)