UCSF

ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (2)
Reactome (11)
Related By:
Pathway (11)
Organism (2)
Gene (7)
Org. Clust. (1)
ChEMBL (17)
Rings (0)

Adenylate Cyclase Type VIII, Mouse (2 Compounds)

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	2	0	0	0
Binding ≤ 1μM	2	0	0	0

Reactome ID	Description	Species
REACT_224974	Adenylate cyclase activating pathway	Mus musculus
REACT_222824	Adenylate cyclase inhibitory pathway	Mus musculus
REACT_198242	CREB phosphorylation through the activation of Adenylate Cyclase	Mus musculus
REACT_250376	G alpha (i) signalling events	Mus musculus
REACT_242871	G alpha (s) signalling events	Mus musculus
REACT_258013	G alpha (z) signalling events	Mus musculus
REACT_210399	Glucagon signaling in metabolic regulation	Mus musculus
REACT_248547	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Mus musculus
REACT_220108	PKA activation	Mus musculus
REACT_220758	PKA activation in glucagon signalling	Mus musculus
REACT_213947	Vasopressin regulates renal water homeostasis via Aquaporins	Mus musculus

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

Adenylate cyclase inhibitory pathway

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

CREB phosphorylation through the activation of Adenylate Cyclase

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2

G alpha (i) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

G alpha (s) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

G alpha (z) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

Glucagon signaling in metabolic regulation

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2

PKA activation

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

PKA activation in glucagon signalling

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

Vasopressin regulates renal water homeostasis via Aquaporins

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	30	7	7	6
ADCY8_RAT	P40146	CHEMBL3082	Adenylate Cyclase Type VIII, Rat	36	24	5	5

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2	0	0	0
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2	0	0	0
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2	0	0	0
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2	0	0	0
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2	0	0	0
ADCY6_MOUSE	Q01341	CHEMBL3015	Adenylate Cyclase Type VI, Mouse	2	0	0	0
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2	0	0	0

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
ADCY8-1-E	Adenylate Cyclase Type VIII (cluster #1 Of 2), Eukaryotic	57	21	9	9
ADCY8-2-E	Adenylate Cyclase Type VIII (cluster #2 Of 2), Eukaryotic	12	11	3	2

Uniprot	Swissprot	Chembl	Description	Number Shared
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	2
ADCY1_MOUSE	O88444	CHEMBL3532	Adenylate Cyclase Type I, Mouse	2
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	2
ADCY2_MOUSE	Q80TL1	CHEMBL3049	Adenylate Cyclase Type II, Mouse	2
ADCY3_HUMAN	O60266	CHEMBL3164	Adenylate Cyclase Type III, Human	2
ADCY3_MOUSE	Q8VHH7	CHEMBL2920	Adenylate Cyclase Type III, Mouse	2
ADCY4_HUMAN	Q8NFM4	CHEMBL2533	Adenylate Cyclase Type IV, Human	2
ADCY4_MOUSE	Q91WF3	CHEMBL2556	Adenylate Cyclase Type IV, Mouse	2
ADCY5_HUMAN	O95622	CHEMBL3189	Adenylate Cyclase Type V, Human	2
ADCY5_MOUSE	P84309	CHEMBL2561	Adenylate Cyclase Type V, Mouse	2
ADCY6_HUMAN	O43306	CHEMBL3221	Adenylate Cyclase Type VI, Human	2
ADCY6_MOUSE	Q01341	CHEMBL3015	Adenylate Cyclase Type VI, Mouse	2
ADCY7_HUMAN	P51828	CHEMBL4922	Adenylate Cyclase Type VII, Human	2
ADCY7_MOUSE	P51829	CHEMBL3016	Adenylate Cyclase Type VII, Mouse	2
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	2
ADCY9_HUMAN	O60503	CHEMBL2655	Adenylate Cyclase Type IX, Human	2
GLR_HUMAN	P47871	CHEMBL1985	Glucagon Receptor, Human	2

Synonyms
Compounds (2)
Related By:
Pathway (11)
Organism (2)
Gene (7)
ChEMBL (17)
Org. Clust. (1)
Rings (0)