UCSF

Indoleamine 2,3-dioxygenase, Human (153 Compounds)

Swissprot:
I23O1_HUMAN
Stitch:
I23O1_HUMAN
UniProt:
P14902
ChEMBL:
CHEMBL4685
Reactome:
REACT_916
PDB:
2D0T (DOCK)
2D0U (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 153 44 25 2
Binding ≤ 1μM 82 15 15 1

Reactome Network (1)

Reactome ID Description Species
REACT_916 Tryptophan catabolism Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
I23O1_MOUSE P28776 CHEMBL1075294 Indoleamine 2,3-dioxygenase 1, Mouse 5 4 2 0

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
I23O1-1-E Indoleamine 2,3-dioxygenase 1 (cluster #1 Of 5), Eukaryotic 104 13 21 1
I23O1-2-E Indoleamine 2,3-dioxygenase 1 (cluster #2 Of 5), Eukaryotic 20 20 1 0
I23O1-3-E Indoleamine 2,3-dioxygenase 1 (cluster #3 Of 5), Eukaryotic 12 5 3 0
I23O1-4-E Indoleamine 2,3-dioxygenase 1 (cluster #4 Of 5), Eukaryotic 8 4 0 1
I23O1-5-E Indoleamine 2,3-dioxygenase 1 (cluster #5 Of 5), Eukaryotic 12 3 0 0
Uniprot Swissprot Chembl Description Number Shared
I23O1_MOUSE P28776 CHEMBL1075294 Indoleamine 2,3-dioxygenase 1, Mouse 4
MPIP2_HUMAN P30305 CHEMBL4804 Dual Specificity Phosphatase Cdc25B, Human 3
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 2
T23O_MOUSE P48776 CHEMBL1075307 Tryptophan 2,3-dioxygenase, Mouse 2
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1
CP51_MYCTU P0A512 CHEMBL5090 Lanosterol 14-alpha Demethylase, Myctu 1
DUS1_MOUSE P28563 CHEMBL5623 Dual Specificity Protein Phosphatase 1, Mouse 1
EST1_HUMAN P23141 CHEMBL2265 Acyl Coenzyme A:cholesterol Acyltransferase, Human 1
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 1
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 1
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 1
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 1
PTPRC_HUMAN P08575 CHEMBL3243 Leukocyte Common Antigen, Human 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1

Most Common Rings