|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 17 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6900 |
0.19 |
Binding ≤ 10μM
|
ANKK1-1-E |
Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.22 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
680 |
0.22 |
Binding ≤ 10μM
|
BRAF-1-E |
Serine/threonine-protein Kinase B-raf (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
83 |
0.25 |
Binding ≤ 10μM
|
CDK19-1-E |
Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.24 |
Binding ≤ 10μM
|
CDK5-1-E |
Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
390 |
0.23 |
Binding ≤ 10μM
|
CDK8-1-E |
Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.24 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8100 |
0.18 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.20 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.31 |
Binding ≤ 10μM
|
DDR2-1-E |
Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
33 |
0.27 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
9100 |
0.18 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9800 |
0.18 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6200 |
0.19 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
880 |
0.22 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3900 |
0.19 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.21 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
430 |
0.23 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
860 |
0.22 |
Binding ≤ 10μM
|
EPHA8-1-E |
Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.24 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4900 |
0.19 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
440 |
0.23 |
Binding ≤ 10μM
|
FAK1-1-E |
Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7100 |
0.18 |
Binding ≤ 10μM
|
FAK2-1-E |
Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
990 |
0.22 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4300 |
0.19 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5000 |
0.19 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
360 |
0.23 |
Binding ≤ 10μM
|
HSPB1-1-E |
Heat Shock Protein Beta-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
58 |
0.26 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
260 |
0.24 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
1200 |
0.21 |
Binding ≤ 10μM
|
LTK-1-E |
Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.21 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2700 |
0.20 |
Binding ≤ 10μM
|
M4K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
90 |
0.25 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3700 |
0.19 |
Binding ≤ 10μM
|
MK09-1-E |
C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
98 |
0.25 |
Binding ≤ 10μM
|
MK10-1-E |
C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
62 |
0.26 |
Binding ≤ 10μM
|
MK11-1-E |
MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.24 |
Binding ≤ 10μM
|
MK12-1-E |
MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
19 |
0.28 |
Binding ≤ 10μM
|
MK13-1-E |
MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
MK14-1-E |
MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
89 |
0.25 |
Binding ≤ 10μM
|
MK15-1-E |
Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3000 |
0.20 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1600 |
0.21 |
Binding ≤ 10μM
|
MLTK-1-E |
Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
860 |
0.22 |
Binding ≤ 10μM
|
MRCKA-1-E |
Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9400 |
0.18 |
Binding ≤ 10μM
|
MRCKB-1-E |
Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
910 |
0.22 |
Binding ≤ 10μM
|
MRCKG-1-E |
Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.21 |
Binding ≤ 10μM
|
MUSK-1-E |
Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.21 |
Binding ≤ 10μM
|
NLK-1-E |
Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.22 |
Binding ≤ 10μM
|
NTRK1-1-E |
Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
770 |
0.22 |
Binding ≤ 10μM
|
NTRK2-1-E |
Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.22 |
Binding ≤ 10μM
|
NTRK3-1-E |
NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
190 |
0.24 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1200 |
0.21 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.21 |
Binding ≤ 10μM
|
RAF1-1-E |
Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.21 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
500 |
0.23 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
86 |
0.25 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.29 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.29 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
20 |
0.28 |
Binding ≤ 10μM
|
TNFA-1-E |
TNF-alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
780 |
0.22 |
Binding ≤ 10μM
|
TNIK-1-E |
TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
10 |
0.29 |
Binding ≤ 10μM
|
TTK-1-E |
Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3300 |
0.20 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
410 |
0.23 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3900 |
0.19 |
Binding ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
7100 |
0.18 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4900 |
0.19 |
Binding ≤ 10μM
|
MK11-1-E |
MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
18 |
0.28 |
Functional ≤ 10μM
|
MK12-1-E |
MAP Kinase P38 Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
18 |
0.28 |
Functional ≤ 10μM
|
MK13-1-E |
MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
18 |
0.28 |
Functional ≤ 10μM
|
MK14-1-E |
MAP Kinase P38 Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
18 |
0.28 |
Functional ≤ 10μM
|
Z100081-1-O |
PBMC (Peripheral Blood Mononuclear Cells) (cluster #1 Of 4), Other |
Other |
30 |
0.27 |
Functional ≤ 10μM
|
Z102213-1-O |
Blood (cluster #1 Of 2), Other |
Other |
780 |
0.22 |
Functional ≤ 10μM
|
Z80548-1-O |
THP-1 (Acute Monocytic Leukemia Cells) (cluster #1 Of 5), Other |
Other |
18 |
0.28 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
6.43 |
12.45 |
-17.33 |
2 |
8 |
0 |
81 |
527.669 |
8 |
↓
|
|
|
Analogs
-
38461223
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 59 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
226 |
0.29 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2900 |
0.24 |
Binding ≤ 10μM
|
AURKA-1-E |
Serine/threonine-protein Kinase Aurora-A (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3800 |
0.24 |
Binding ≤ 10μM |
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
440 |
0.28 |
Binding ≤ 10μM
|
AURKC-1-E |
Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
210 |
0.29 |
Binding ≤ 10μM
|
BRAF-1-E |
Serine/threonine-protein Kinase B-raf (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
76 |
0.31 |
Binding ≤ 10μM
|
CDK14-1-E |
Serine/threonine-protein Kinase PFTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2900 |
0.24 |
Binding ≤ 10μM
|
CDK15-1-E |
Serine/threonine-protein Kinase PFTAIRE-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2900 |
0.24 |
Binding ≤ 10μM
|
CDK17-1-E |
Serine/threonine-protein Kinase PCTAIRE-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.25 |
Binding ≤ 10μM
|
CDK19-1-E |
Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
250 |
0.29 |
Binding ≤ 10μM
|
CDK5-1-E |
Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6200 |
0.23 |
Binding ≤ 10μM
|
CDK7-1-E |
Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
140 |
0.30 |
Binding ≤ 10μM
|
CDK8-1-E |
Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
310 |
0.28 |
Binding ≤ 10μM
|
CDKL2-1-E |
Cyclin-dependent Kinase-like 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
130 |
0.30 |
Binding ≤ 10μM
|
CDKL3-1-E |
Cyclin-dependent Kinase-like 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
490 |
0.28 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
58 |
0.32 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2900 |
0.24 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6200 |
0.23 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.38 |
Binding ≤ 10μM
|
DDR2-1-E |
Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.36 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.24 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4800 |
0.23 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6400 |
0.23 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3000 |
0.24 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
360 |
0.28 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
370 |
0.28 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
670 |
0.27 |
Binding ≤ 10μM
|
EPHA8-1-E |
Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
960 |
0.26 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3000 |
0.24 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.25 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3900 |
0.24 |
Binding ≤ 10μM
|
EPHB6-1-E |
Ephrin Type-B Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
240 |
0.29 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
580 |
0.27 |
Binding ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2700 |
0.24 |
Binding ≤ 10μM
|
FGFR3-1-E |
Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5900 |
0.23 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
82 |
0.31 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
510 |
0.28 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
530 |
0.27 |
Binding ≤ 10μM
|
HIPK1-1-E |
Homeodomain-interacting Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.26 |
Binding ≤ 10μM
|
HIPK2-1-E |
Homeodomain-interacting Protein Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.25 |
Binding ≤ 10μM
|
HIPK3-1-E |
Homeodomain-interacting Protein Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
390 |
0.28 |
Binding ≤ 10μM
|
HIPK4-1-E |
Homeodomain-interacting Protein Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.37 |
Binding ≤ 10μM
|
INSR-1-E |
Insulin Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5300 |
0.23 |
Binding ≤ 10μM
|
KC1A-1-E |
Casein Kinase I Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
250 |
0.29 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
740 |
0.27 |
Binding ≤ 10μM
|
KS6A6-1-E |
Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7500 |
0.22 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
6900 |
0.23 |
Binding ≤ 10μM
|
LIMK1-1-E |
LIM Domain Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.25 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3000 |
0.24 |
Binding ≤ 10μM
|
M3K7-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
690 |
0.27 |
Binding ≤ 10μM
|
M4K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
4800 |
0.23 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.25 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3600 |
0.24 |
Binding ≤ 10μM
|
MK09-1-E |
C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
3600 |
0.24 |
Binding ≤ 10μM
|
MK11-1-E |
MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
230 |
0.29 |
Binding ≤ 10μM
|
MK12-1-E |
MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9900 |
0.22 |
Binding ≤ 10μM
|
MK13-1-E |
MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6600 |
0.23 |
Binding ≤ 10μM
|
MK14-1-E |
MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
85 |
0.31 |
Binding ≤ 10μM
|
MK15-1-E |
Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
46 |
0.32 |
Binding ≤ 10μM
|
MKNK1-1-E |
MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
230 |
0.29 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
250 |
0.29 |
Binding ≤ 10μM
|
MLTK-1-E |
Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.36 |
Binding ≤ 10μM
|
MUSK-1-E |
Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
130 |
0.30 |
Binding ≤ 10μM
|
MYLK2-1-E |
Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.26 |
Binding ≤ 10μM
|
NLK-1-E |
Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
640 |
0.27 |
Binding ≤ 10μM
|
NTRK1-1-E |
Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6300 |
0.23 |
Binding ≤ 10μM
|
NTRK2-1-E |
Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.25 |
Binding ≤ 10μM
|
NTRK3-1-E |
NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
600 |
0.27 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
62 |
0.32 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
57 |
0.32 |
Binding ≤ 10μM
|
PLK4-1-E |
Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.23 |
Binding ≤ 10μM
|
RAF1-1-E |
Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.36 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.35 |
Binding ≤ 10μM
|
RIPK2-1-E |
Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3600 |
0.24 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1600 |
0.25 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
390 |
0.28 |
Binding ≤ 10μM
|
SRMS-1-E |
Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9800 |
0.22 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
150 |
0.30 |
Binding ≤ 10μM
|
STK33-1-E |
Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.25 |
Binding ≤ 10μM
|
STK36-1-E |
Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5400 |
0.23 |
Binding ≤ 10μM
|
TAOK1-1-E |
Serine/threonine-protein Kinase TAO1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
540 |
0.27 |
Binding ≤ 10μM
|
TAOK3-1-E |
Serine/threonine-protein Kinase TAO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2700 |
0.24 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
68 |
0.31 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3000 |
0.24 |
Binding ≤ 10μM
|
TNI3K-1-E |
Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
280 |
0.29 |
Binding ≤ 10μM
|
TNK1-1-E |
Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2300 |
0.25 |
Binding ≤ 10μM
|
TTK-1-E |
Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.24 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.23 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
31 |
0.33 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
93 |
0.31 |
Binding ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
95 |
0.31 |
Binding ≤ 10μM
|
YSK4-1-E |
SPS1/STE20-related Protein Kinase YSK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
99 |
0.31 |
Binding ≤ 10μM
|
BRAF-1-E |
Serine/threonine-protein Kinase B-raf (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6100 |
0.23 |
Functional ≤ 10μM
|
MP2K1-2-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
3300 |
0.24 |
Functional ≤ 10μM
|
RAF1-2-E |
Serine/threonine-protein Kinase RAF (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
3300 |
0.24 |
Functional ≤ 10μM
|
Z100405-1-O |
MV4-11 (Myeloid Leukemia Cells) (cluster #1 Of 1), Other |
Other |
15 |
0.34 |
Functional ≤ 10μM |
Z103203-1-O |
A375 (cluster #1 Of 3), Other |
Other |
5600 |
0.23 |
Functional ≤ 10μM |
Z50425-3-O |
Plasmodium Falciparum (cluster #3 Of 22), Other |
Other |
509 |
0.28 |
Functional ≤ 10μM
|
Z80224-1-O |
MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other |
Other |
8830 |
0.22 |
Functional ≤ 10μM
|
Z80485-1-O |
SK-MEL-28 (Melanoma Cells) (cluster #1 Of 6), Other |
Other |
1300 |
0.26 |
Functional ≤ 10μM
|
Z80548-1-O |
THP-1 (Acute Monocytic Leukemia Cells) (cluster #1 Of 5), Other |
Other |
310 |
0.28 |
Functional ≤ 10μM |
Z80682-1-O |
A549 (Lung Carcinoma Cells) (cluster #1 Of 11), Other |
Other |
5210 |
0.23 |
Functional ≤ 10μM
|
Z81057-1-O |
HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other |
Other |
1 |
0.39 |
Functional ≤ 10μM
|
Z81252-3-O |
MDA-MB-231 (Breast Adenocarcinoma Cells) (cluster #3 Of 11), Other |
Other |
7620 |
0.22 |
Functional ≤ 10μM
|
Z100091-1-O |
HS27 (Fibroblast Cells) (cluster #1 Of 1), Other |
Other |
7850 |
0.22 |
ADME/T ≤ 10μM
|
Z103203-1-O |
A375 (cluster #1 Of 1), Other |
Other |
2200 |
0.25 |
ADME/T ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
4.76 |
6.55 |
-16.07 |
3 |
7 |
0 |
92 |
464.831 |
6 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 35 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
590 |
0.26 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
ACK1-1-E |
Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.35 |
Binding ≤ 10μM
|
ACV1B-1-E |
Activin Receptor Type-1B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.27 |
Binding ≤ 10μM
|
ACVL1-1-E |
Serine/threonine-protein Kinase Receptor R3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
460 |
0.27 |
Binding ≤ 10μM
|
ACVR1-1-E |
Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
620 |
0.26 |
Binding ≤ 10μM
|
ADCK3-1-E |
Chaperone Activity Of Bc1 Complex-like, Mitochondrial (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
190 |
0.29 |
Binding ≤ 10μM
|
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6485 |
0.22 |
Binding ≤ 10μM |
AVR2A-1-E |
Activin Receptor Type-2A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
210 |
0.28 |
Binding ≤ 10μM
|
AVR2B-1-E |
Activin Receptor Type-2B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.26 |
Binding ≤ 10μM
|
BCR-1-E |
Breakpoint Cluster Region Protein (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
BMX-1-E |
Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
BRAF-1-E |
Serine/threonine-protein Kinase B-raf (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.26 |
Binding ≤ 10μM
|
BTK-1-E |
Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.35 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.35 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
DDR2-1-E |
Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.36 |
Binding ≤ 10μM
|
DMPK-1-E |
Myotonin-protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.25 |
Binding ≤ 10μM
|
E2AK4-1-E |
Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.25 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
79 |
0.30 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.36 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
137 |
0.29 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
EPHA8-1-E |
Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.36 |
Binding ≤ 10μM
|
EPHB3-1-E |
Ephrin Type-B Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.35 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
ERBB2-2-E |
Receptor Protein-tyrosine Kinase ErbB-2 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
710 |
0.26 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
880 |
0.26 |
Binding ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.25 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8100 |
0.22 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
FYN-1-E |
Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
GAK-1-E |
Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3 |
0.36 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
JAK2-1-E |
Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.25 |
Binding ≤ 10μM
|
KC1A-1-E |
Casein Kinase I Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
KC1E-1-E |
Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1500 |
0.25 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
93 |
0.30 |
Binding ≤ 10μM
|
KSYK-1-E |
Tyrosine-protein Kinase SYK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2900 |
0.23 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
LIMK1-1-E |
LIM Domain Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.26 |
Binding ≤ 10μM
|
LIMK2-1-E |
LIM Domain Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
86 |
0.30 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
M3K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
310 |
0.28 |
Binding ≤ 10μM
|
M4K1-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
980 |
0.25 |
Binding ≤ 10μM
|
M4K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
640 |
0.26 |
Binding ≤ 10μM
|
M4K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3100 |
0.23 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
45 |
0.31 |
Binding ≤ 10μM
|
MK11-1-E |
MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
410 |
0.27 |
Binding ≤ 10μM
|
MK12-1-E |
MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
100 |
0.30 |
Binding ≤ 10μM
|
MK13-1-E |
MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.30 |
Binding ≤ 10μM
|
MK14-1-E |
MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
495 |
0.27 |
Binding ≤ 10μM
|
MLTK-1-E |
Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
45 |
0.31 |
Binding ≤ 10μM
|
MP2K1-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
1700 |
0.24 |
Binding ≤ 10μM
|
MP2K2-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.24 |
Binding ≤ 10μM
|
MRCKA-1-E |
Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2000 |
0.24 |
Binding ≤ 10μM
|
MRCKB-1-E |
Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.24 |
Binding ≤ 10μM
|
MRCKG-1-E |
Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.25 |
Binding ≤ 10μM
|
MST4-1-E |
Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.24 |
Binding ≤ 10μM
|
NLK-1-E |
Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
260 |
0.28 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
63 |
0.31 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
28 |
0.32 |
Binding ≤ 10μM
|
PMYT1-1-E |
Tyrosine- And Threonine-specific Cdc2-inhibitory Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
130 |
0.29 |
Binding ≤ 10μM
|
PTK6-1-E |
Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.34 |
Binding ≤ 10μM |
RAF1-1-E |
Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.26 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
730 |
0.26 |
Binding ≤ 10μM
|
RIPK2-1-E |
Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
31 |
0.32 |
Binding ≤ 10μM
|
SIK1-1-E |
Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.36 |
Binding ≤ 10μM
|
SIK2-1-E |
Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.35 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
720 |
0.26 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
14 |
0.33 |
Binding ≤ 10μM
|
SRMS-1-E |
Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
13 |
0.33 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.25 |
Binding ≤ 10μM
|
STK36-1-E |
Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
210 |
0.28 |
Binding ≤ 10μM
|
TBA1A-1-E |
Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
55 |
0.31 |
Binding ≤ 10μM
|
TEC-1-E |
Tyrosine-protein Kinase TEC (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
297 |
0.28 |
Binding ≤ 10μM
|
TESK1-1-E |
Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
33 |
0.32 |
Binding ≤ 10μM
|
TGFR1-1-E |
TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
230 |
0.28 |
Binding ≤ 10μM
|
TGFR2-1-E |
TGF-beta Receptor Type II (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2900 |
0.23 |
Binding ≤ 10μM
|
TNI3K-1-E |
Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
11 |
0.34 |
Binding ≤ 10μM
|
TNIK-1-E |
TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2000 |
0.24 |
Binding ≤ 10μM
|
TXK-1-E |
Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.37 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5000 |
0.22 |
Binding ≤ 10μM
|
VGFR2-2-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
2360 |
0.24 |
Binding ≤ 10μM
|
WEE1-1-E |
Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7000 |
0.22 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.38 |
Binding ≤ 10μM
|
Z80186-1-O |
K562 (Erythroleukemia Cells) (cluster #1 Of 11), Other |
Other |
1 |
0.38 |
Functional ≤ 10μM
|
Z80390-1-O |
PC-3 (Prostate Carcinoma Cells) (cluster #1 Of 10), Other |
Other |
9 |
0.34 |
Functional ≤ 10μM
|
Z81017-1-O |
WiDr (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other |
Other |
52 |
0.31 |
Functional ≤ 10μM
|
Z81252-3-O |
MDA-MB-231 (Breast Adenocarcinoma Cells) (cluster #3 Of 11), Other |
Other |
12 |
0.34 |
Functional ≤ 10μM
|
Z81338-1-O |
T-cells (cluster #1 Of 3), Other |
Other |
3 |
0.36 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
3.13 |
7.33 |
-37.83 |
4 |
9 |
1 |
108 |
489.025 |
7 |
↓
|
Mid
Mid (pH 6-8)
|
3.13 |
7.4 |
-39.94 |
4 |
9 |
1 |
108 |
489.025 |
7 |
↓
|
Mid
Mid (pH 6-8)
|
3.13 |
7.04 |
-18.14 |
3 |
9 |
0 |
107 |
488.017 |
7 |
↓
|
|
|
Analogs
-
4095791
-
-
12501465
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 3 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
AAK1-1-E |
Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
AAPK1-1-E |
AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM
|
AAPK2-1-E |
AMP-activated Protein Kinase, Alpha-2 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
12 |
0.32 |
Binding ≤ 10μM
|
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
91 |
0.28 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
160 |
0.27 |
Binding ≤ 10μM
|
ACK1-1-E |
Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
17 |
0.31 |
Binding ≤ 10μM
|
ACV1B-1-E |
Activin Receptor Type-1B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
680 |
0.25 |
Binding ≤ 10μM
|
ACVR1-1-E |
Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
470 |
0.25 |
Binding ≤ 10μM
|
AKT1-2-E |
RAC-alpha Serine/threonine-protein Kinase (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
AKT2-2-E |
Serine/threonine-protein Kinase AKT2 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM
|
AKT3-2-E |
Serine/threonine-protein Kinase AKT3 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM
|
ALK-1-E |
ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
32 |
0.30 |
Binding ≤ 10μM
|
ANKK1-1-E |
Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.26 |
Binding ≤ 10μM
|
AURKA-1-E |
Serine/threonine-protein Kinase Aurora-A (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
22 |
0.31 |
Binding ≤ 10μM
|
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
19 |
0.31 |
Binding ≤ 10μM
|
AURKC-1-E |
Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
23 |
0.31 |
Binding ≤ 10μM
|
AVR2B-1-E |
Activin Receptor Type-2B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4600 |
0.21 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
15 |
0.31 |
Binding ≤ 10μM
|
BMP2K-1-E |
BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
BMR1A-1-E |
Bone Morphogenetic Protein Receptor Type-1A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3700 |
0.22 |
Binding ≤ 10μM
|
BMX-1-E |
Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
410 |
0.26 |
Binding ≤ 10μM
|
BRSK1-1-E |
BR Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
26 |
0.30 |
Binding ≤ 10μM
|
BRSK2-1-E |
BR Serine/threonine-protein Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
BTK-1-E |
Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
710 |
0.25 |
Binding ≤ 10μM
|
CCNB1-1-E |
G2/mitotic-specific Cyclin B1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
CCNB2-1-E |
G2/mitotic-specific Cyclin B2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
CCNB3-1-E |
G2/mitotic-specific Cyclin B3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
CCNE1-1-E |
G1/S-specific Cyclin E1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
20 |
0.31 |
Binding ≤ 10μM
|
CCNE2-1-E |
G1/S-specific Cyclin E2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
20 |
0.31 |
Binding ≤ 10μM
|
CDK1-1-E |
Cyclin-dependent Kinase 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM
|
CDK14-1-E |
Serine/threonine-protein Kinase PFTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
160 |
0.27 |
Binding ≤ 10μM
|
CDK16-1-E |
Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
25 |
0.30 |
Binding ≤ 10μM
|
CDK17-1-E |
Serine/threonine-protein Kinase PCTAIRE-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
96 |
0.28 |
Binding ≤ 10μM
|
CDK18-1-E |
Serine/threonine-protein Kinase PCTAIRE-3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.26 |
Binding ≤ 10μM
|
CDK19-1-E |
Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
190 |
0.27 |
Binding ≤ 10μM
|
CDK2-1-E |
Cyclin-dependent Kinase 2 (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM
|
CDK3-1-E |
Cyclin-dependent Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
CDK4-2-E |
Cyclin-dependent Kinase 4 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
18 |
0.31 |
Binding ≤ 10μM
|
CDK5-1-E |
Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
89 |
0.28 |
Binding ≤ 10μM
|
CDK6-1-E |
Cyclin-dependent Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
116 |
0.28 |
Binding ≤ 10μM
|
CDK7-1-E |
Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
45 |
0.29 |
Binding ≤ 10μM
|
CDK8-1-E |
Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
510 |
0.25 |
Binding ≤ 10μM
|
CDK9-1-E |
Cyclin-dependent Kinase 9 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
CHK1-1-E |
Serine/threonine-protein Kinase Chk1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
10 |
0.32 |
Binding ≤ 10μM
|
CHK2-1-E |
Serine/threonine-protein Kinase Chk2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
CLK1-2-E |
Dual Specificty Protein Kinase CLK1 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
32 |
0.30 |
Binding ≤ 10μM
|
CLK2-1-E |
Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM
|
CLK3-1-E |
Dual Specificity Protein Kinase CLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
910 |
0.24 |
Binding ≤ 10μM
|
CLK4-1-E |
Dual Specificity Protein Kinase CLK4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
10 |
0.32 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
12 |
0.32 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
440 |
0.25 |
Binding ≤ 10μM
|
CSK21-1-E |
Casein Kinase II Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
7620 |
0.20 |
Binding ≤ 10μM
|
CSK22-1-E |
Casein Kinase II Alpha (prime) (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
CSK2B-1-E |
Casein Kinase II Beta (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
7000 |
0.21 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
340 |
0.26 |
Binding ≤ 10μM
|
DAPK1-1-E |
Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
DAPK2-1-E |
Death-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
DAPK3-1-E |
Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1500 |
0.23 |
Binding ≤ 10μM
|
DCLK1-1-E |
Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.28 |
Binding ≤ 10μM
|
DCLK2-1-E |
Serine/threonine-protein Kinase DCLK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
73 |
0.29 |
Binding ≤ 10μM
|
DCLK3-1-E |
Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
17 |
0.31 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
19 |
0.31 |
Binding ≤ 10μM
|
DDR2-1-E |
Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
42 |
0.30 |
Binding ≤ 10μM
|
DMPK-1-E |
Myotonin-protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
DYR1B-1-E |
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
28 |
0.30 |
Binding ≤ 10μM
|
E2AK2-1-E |
Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.28 |
Binding ≤ 10μM |
E2AK2-1-E |
Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
360 |
0.26 |
Binding ≤ 10μM
|
E2AK4-1-E |
Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
16 |
0.31 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
96 |
0.28 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
300 |
0.26 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
870 |
0.24 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
55 |
0.29 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
710 |
0.25 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
95 |
0.28 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
290 |
0.26 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
690 |
0.25 |
Binding ≤ 10μM
|
EPHA8-1-E |
Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
300 |
0.26 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
590 |
0.25 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.23 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
233 |
0.27 |
Binding ≤ 10μM
|
ERBB4-1-E |
Receptor Protein-tyrosine Kinase ErbB-4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
282 |
0.26 |
Binding ≤ 10μM
|
FAK1-1-E |
Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
68 |
0.29 |
Binding ≤ 10μM
|
FAK2-1-E |
Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
FER-1-E |
Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
30 |
0.30 |
Binding ≤ 10μM
|
FES-1-E |
Tyrosine-protein Kinase FES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
23 |
0.31 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
90 |
0.28 |
Binding ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
420 |
0.26 |
Binding ≤ 10μM
|
FGFR3-1-E |
Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
88 |
0.28 |
Binding ≤ 10μM
|
FGFR4-1-E |
Fibroblast Growth Factor Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
420 |
0.26 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
30 |
0.30 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
45 |
0.29 |
Binding ≤ 10μM
|
FYN-1-E |
Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
83 |
0.28 |
Binding ≤ 10μM
|
GAK-1-E |
Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
68 |
0.29 |
Binding ≤ 10μM
|
GSK3A-1-E |
Glycogen Synthase Kinase-3 Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
140 |
0.27 |
Binding ≤ 10μM
|
GSK3B-1-E |
Glycogen Synthase Kinase-3 Beta (cluster #1 Of 7), Eukaryotic |
Eukaryotes |
89 |
0.28 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
20 |
0.31 |
Binding ≤ 10μM
|
HIPK1-1-E |
Homeodomain-interacting Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2639 |
0.22 |
Binding ≤ 10μM
|
IGF1R-1-E |
Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
35 |
0.30 |
Binding ≤ 10μM
|
IKKA-2-E |
Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
39 |
0.30 |
Binding ≤ 10μM
|
IKKB-1-E |
Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
771 |
0.24 |
Binding ≤ 10μM
|
IKKE-1-E |
Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM
|
INSR-1-E |
Insulin Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.27 |
Binding ≤ 10μM
|
INSRR-1-E |
Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
81 |
0.28 |
Binding ≤ 10μM
|
IRAK3-1-E |
Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
13 |
0.32 |
Binding ≤ 10μM
|
IRAK4-1-E |
Interleukin-1 Receptor-associated Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
34 |
0.30 |
Binding ≤ 10μM
|
ITK-1-E |
Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
19 |
0.31 |
Binding ≤ 10μM
|
JAK2-1-E |
Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM
|
JAK3-1-E |
Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
KAP2-1-E |
CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.28 |
Binding ≤ 10μM
|
KAPCA-1-E |
CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
27 |
0.30 |
Binding ≤ 10μM
|
KAPCB-1-E |
CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
KAPCG-1-E |
CAMP-dependent Protein Kinase, Gamma Catalytic Subunit (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
80 |
0.28 |
Binding ≤ 10μM
|
KC1A-1-E |
Casein Kinase I Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.23 |
Binding ≤ 10μM
|
KC1AL-1-E |
Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
250 |
0.26 |
Binding ≤ 10μM
|
KC1D-1-E |
Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.23 |
Binding ≤ 10μM
|
KC1E-1-E |
Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1400 |
0.23 |
Binding ≤ 10μM
|
KC1G1-1-E |
Casein Kinase I Gamma 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1400 |
0.23 |
Binding ≤ 10μM
|
KC1G2-1-E |
Casein Kinase I Gamma 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
780 |
0.24 |
Binding ≤ 10μM
|
KCC1A-1-E |
CaM Kinase I Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
40 |
0.30 |
Binding ≤ 10μM
|
KCC1D-1-E |
CaM Kinase I Delta (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2 |
0.35 |
Binding ≤ 10μM
|
KCC1G-1-E |
CaM Kinase I Gamma (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
53 |
0.29 |
Binding ≤ 10μM
|
KCC2A-1-E |
CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
KCC2B-1-E |
CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
KCC2D-1-E |
CaM Kinase II Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
KCC2G-1-E |
CaM Kinase II Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
KCC4-1-E |
CaM Kinase IV (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
41 |
0.30 |
Binding ≤ 10μM
|
KGP1-1-E |
CGMP-dependent Protein Kinase 1 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
32 |
0.30 |
Binding ≤ 10μM
|
KGP2-1-E |
CGMP-dependent Protein Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
16 |
0.31 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
10 |
0.32 |
Binding ≤ 10μM
|
KKCC1-1-E |
CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
KKCC2-1-E |
CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
KPB1-1-E |
Phosphorylase Kinase Alpha M Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
KPB2-1-E |
Phosphorylase Kinase Alpha L Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
KPBB-1-E |
Phosphorylase Kinase Beta Subunit (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
KPCA-1-E |
Protein Kinase C Alpha (cluster #1 Of 6), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KPCB-1-E |
Protein Kinase C Beta (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM |
KPCD-1-E |
Protein Kinase C Delta (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KPCD1-1-E |
Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KPCD2-1-E |
Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
72 |
0.29 |
Binding ≤ 10μM
|
KPCD3-1-E |
Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KPCE-1-E |
Protein Kinase C Epsilon (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KPCG-1-E |
Protein Kinase C Gamma (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM |
KPCI-1-E |
Protein Kinase C Iota (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KPCL-2-E |
Protein Kinase C Eta (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM |
KPCT-1-E |
Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM |
KPCZ-1-E |
Protein Kinase C Zeta (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM |
KS6A1-1-E |
Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM |
KS6A2-1-E |
Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM
|
KS6A3-1-E |
Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
69 |
0.29 |
Binding ≤ 10μM
|
KS6A4-1-E |
Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM |
KS6A5-1-E |
Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
890 |
0.24 |
Binding ≤ 10μM
|
KS6A6-1-E |
Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM |
KS6B1-1-E |
Ribosomal Protein S6 Kinase 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM |
KS6B2-1-E |
Ribosomal Protein S6 Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM |
KSYK-1-E |
Tyrosine-protein Kinase SYK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
LATS1-1-E |
Serine/threonine-protein Kinase LATS1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
42 |
0.30 |
Binding ≤ 10μM
|
LATS2-1-E |
Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
17 |
0.31 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
LIMK1-1-E |
LIM Domain Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
690 |
0.25 |
Binding ≤ 10μM
|
LIMK2-1-E |
LIM Domain Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9200 |
0.20 |
Binding ≤ 10μM
|
LTK-1-E |
Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
37 |
0.30 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
40 |
0.30 |
Binding ≤ 10μM
|
M3K10-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
52 |
0.29 |
Binding ≤ 10μM
|
M3K11-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 11 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
20 |
0.31 |
Binding ≤ 10μM
|
M3K14-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 14 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2300 |
0.23 |
Binding ≤ 10μM
|
M3K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.23 |
Binding ≤ 10μM
|
M3K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
37 |
0.30 |
Binding ≤ 10μM
|
M3K7-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
35 |
0.30 |
Binding ≤ 10μM
|
M3K9-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
10 |
0.32 |
Binding ≤ 10μM
|
M4K1-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
M4K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM
|
M4K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
24 |
0.30 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
26 |
0.30 |
Binding ≤ 10μM
|
MAPK2-1-E |
MAP Kinase-activated Protein Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
880 |
0.24 |
Binding ≤ 10μM
|
MARK1-1-E |
Serine/threonine-protein Kinase MARK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
MARK2-1-E |
MAP/microtubule Affinity-regulating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
MARK3-1-E |
Serine/threonine-protein Kinase C-TAK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
MARK4-1-E |
MAP/microtubule Affinity-regulating Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM
|
MELK-1-E |
Maternal Embryonic Leucine Zipper Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
33 |
0.30 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
MET-1-E |
Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
190 |
0.27 |
Binding ≤ 10μM
|
MINK1-1-E |
Misshapen-like Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
MK01-1-E |
Mitogen-activated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7300 |
0.21 |
Binding ≤ 10μM
|
MK03-1-E |
MAP Kinase ERK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8400 |
0.20 |
Binding ≤ 10μM
|
MK07-1-E |
Mitogen-activated Protein Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.23 |
Binding ≤ 10μM
|
MK08-1-E |
Mitogen-activated Protein Kinase 8 (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
520 |
0.25 |
Binding ≤ 10μM
|
MK09-1-E |
C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1100 |
0.24 |
Binding ≤ 10μM
|
MK10-1-E |
C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
340 |
0.26 |
Binding ≤ 10μM
|
MK11-1-E |
MAP Kinase P38 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.24 |
Binding ≤ 10μM
|
MK12-1-E |
MAP Kinase P38 Gamma (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
92 |
0.28 |
Binding ≤ 10μM
|
MK13-1-E |
MAP Kinase P38 Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.24 |
Binding ≤ 10μM
|
MK14-1-E |
MAP Kinase P38 Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1000 |
0.24 |
Binding ≤ 10μM
|
MK15-1-E |
Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
35 |
0.30 |
Binding ≤ 10μM
|
MKNK1-1-E |
MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
170 |
0.27 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
22 |
0.31 |
Binding ≤ 10μM
|
MP2K1-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
670 |
0.25 |
Binding ≤ 10μM
|
MP2K2-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
28 |
0.30 |
Binding ≤ 10μM
|
MP2K3-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.33 |
Binding ≤ 10μM
|
MP2K4-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
70 |
0.29 |
Binding ≤ 10μM
|
MP2K6-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
MRCKA-1-E |
Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
57 |
0.29 |
Binding ≤ 10μM
|
MRCKB-1-E |
Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
42 |
0.30 |
Binding ≤ 10μM
|
MRCKG-1-E |
Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
37 |
0.30 |
Binding ≤ 10μM
|
MST4-1-E |
Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
140 |
0.27 |
Binding ≤ 10μM
|
MUSK-1-E |
Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
86 |
0.28 |
Binding ≤ 10μM
|
MYLK-1-E |
Myosin Light Chain Kinase, Smooth Muscle (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
40 |
0.30 |
Binding ≤ 10μM
|
MYLK2-1-E |
Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
61 |
0.29 |
Binding ≤ 10μM
|
MYLK4-1-E |
Myosin Light Chain Kinase Family Member 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
470 |
0.25 |
Binding ≤ 10μM
|
MYO3A-1-E |
Myosin IIIA (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
500 |
0.25 |
Binding ≤ 10μM
|
MYO3B-1-E |
Myosin-IIIB (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
300 |
0.26 |
Binding ≤ 10μM
|
NEK1-1-E |
Serine/threonine-protein Kinase Nek1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
860 |
0.24 |
Binding ≤ 10μM
|
NEK2-1-E |
Serine/threonine-protein Kinase NEK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
750 |
0.24 |
Binding ≤ 10μM
|
NEK5-1-E |
Serine/threonine-protein Kinase Nek5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
810 |
0.24 |
Binding ≤ 10μM
|
NEK7-1-E |
Serine/threonine-protein Kinase NEK7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.21 |
Binding ≤ 10μM
|
NEK9-1-E |
Serine/threonine-protein Kinase NEK9 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6700 |
0.21 |
Binding ≤ 10μM
|
NLK-1-E |
Serine/threonine Protein Kinase NLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.27 |
Binding ≤ 10μM
|
NTRK1-1-E |
Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
NTRK2-1-E |
Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
NTRK3-1-E |
NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
17 |
0.31 |
Binding ≤ 10μM
|
NUAK1-1-E |
NUAK Family SNF1-like Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4 |
0.34 |
Binding ≤ 10μM
|
NUAK2-1-E |
NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
P90584-2-E |
Protein Kinase Pfmrk (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
4000 |
0.22 |
Binding ≤ 10μM
|
PAK1-1-E |
Serine/threonine-protein Kinase PAK 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.35 |
Binding ≤ 10μM
|
PAK2-1-E |
Serine/threonine-protein Kinase PAK 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
PAK3-1-E |
Serine/threonine-protein Kinase PAK 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
PAK4-1-E |
Serine/threonine-protein Kinase PAK 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM
|
PAK6-1-E |
Serine/threonine-protein Kinase PAK6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
PAK7-1-E |
Serine/threonine-protein Kinase PAK7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
PDPK1-1-E |
3-phosphoinositide Dependent Protein Kinase-1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2 |
0.35 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2 |
0.35 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
PHKG1-1-E |
Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM |
PHKG2-1-E |
Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM |
PI42B-1-E |
Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
77 |
0.28 |
Binding ≤ 10μM
|
PI51A-1-E |
Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
43 |
0.29 |
Binding ≤ 10μM
|
PIM1-1-E |
Serine/threonine-protein Kinase PIM1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.32 |
Binding ≤ 10μM
|
PIM2-1-E |
Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
PIM3-1-E |
Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
PKN1-1-E |
Protein Kinase N1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
PKN2-1-E |
Protein Kinase N2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
PLK1-1-E |
Serine/threonine-protein Kinase PLK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
190 |
0.27 |
Binding ≤ 10μM
|
PLK2-1-E |
Serine/threonine-protein Kinase PLK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
197 |
0.27 |
Binding ≤ 10μM
|
PLK3-1-E |
Serine/threonine-protein Kinase PLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
910 |
0.24 |
Binding ≤ 10μM
|
PLK4-1-E |
Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
PRKX-1-E |
Serine/threonine-protein Kinase PRKX (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
13 |
0.32 |
Binding ≤ 10μM
|
PTK6-1-E |
Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2300 |
0.23 |
Binding ≤ 10μM
|
Q95J97-1-E |
CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
80 |
0.28 |
Binding ≤ 10μM
|
RAF1-1-E |
Serine/threonine-protein Kinase RAF (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
28 |
0.30 |
Binding ≤ 10μM
|
RIOK1-1-E |
Serine/threonine-protein Kinase RIO1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
130 |
0.28 |
Binding ≤ 10μM
|
RIOK3-1-E |
Serine/threonine-protein Kinase RIO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
76 |
0.28 |
Binding ≤ 10μM
|
RIPK2-1-E |
Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5200 |
0.21 |
Binding ≤ 10μM
|
ROCK1-1-E |
Rho-associated Protein Kinase 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
ROS1-1-E |
Proto-oncogene Tyrosine-protein Kinase ROS (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
30 |
0.30 |
Binding ≤ 10μM
|
SIK1-1-E |
Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.35 |
Binding ≤ 10μM
|
SIK2-1-E |
Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.36 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
86 |
0.28 |
Binding ≤ 10μM
|
SRMS-1-E |
Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
740 |
0.25 |
Binding ≤ 10μM
|
SRPK1-1-E |
Serine/threonine-protein Kinase SRPK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
SRPK2-1-E |
Serine/threonine-protein Kinase SRPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
67 |
0.29 |
Binding ≤ 10μM
|
ST17A-1-E |
Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
23 |
0.31 |
Binding ≤ 10μM
|
ST17B-1-E |
Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
26 |
0.30 |
Binding ≤ 10μM
|
ST32B-1-E |
Serine/threonine-protein Kinase 32B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
98 |
0.28 |
Binding ≤ 10μM
|
ST32C-1-E |
Serine/threonine-protein Kinase 32C (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
310 |
0.26 |
Binding ≤ 10μM
|
ST38L-1-E |
Serine/threonine-protein Kinase 38-like (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
77 |
0.28 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
STK11-1-E |
Serine/threonine-protein Kinase 11 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
61 |
0.29 |
Binding ≤ 10μM
|
STK16-1-E |
Serine/threonine-protein Kinase 16 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.26 |
Binding ≤ 10μM
|
STK24-1-E |
Serine/threonine-protein Kinase 24 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
120 |
0.28 |
Binding ≤ 10μM
|
STK25-1-E |
Serine/threonine-protein Kinase 25 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.28 |
Binding ≤ 10μM
|
STK3-1-E |
Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
STK33-1-E |
Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.35 |
Binding ≤ 10μM
|
STK36-1-E |
Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6700 |
0.21 |
Binding ≤ 10μM
|
STK4-1-E |
Serine/threonine-protein Kinase MST1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
SYK-1-E |
Lysyl-tRNA Synthetase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.32 |
Binding ≤ 10μM
|
TAB1-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 7-interacting Protein 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
35 |
0.30 |
Binding ≤ 10μM
|
TBA1A-1-E |
Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
770 |
0.24 |
Binding ≤ 10μM
|
TEC-1-E |
Tyrosine-protein Kinase TEC (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.24 |
Binding ≤ 10μM
|
TESK1-1-E |
Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
320 |
0.26 |
Binding ≤ 10μM
|
TGFR1-1-E |
TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2000 |
0.23 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
65 |
0.29 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
52 |
0.29 |
Binding ≤ 10μM
|
TLK1-1-E |
Serine/threonine-protein Kinase Tousled-like 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
27 |
0.30 |
Binding ≤ 10μM
|
TLK2-1-E |
Serine/threonine-protein Kinase Tousled-like 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
16 |
0.31 |
Binding ≤ 10μM
|
TNI3K-1-E |
Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.24 |
Binding ≤ 10μM
|
TNIK-1-E |
TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.33 |
Binding ≤ 10μM
|
TNK1-1-E |
Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
TSSK1-1-E |
Testis-specific Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
24 |
0.30 |
Binding ≤ 10μM
|
TTK-1-E |
Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
61 |
0.29 |
Binding ≤ 10μM
|
TXK-1-E |
Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
230 |
0.27 |
Binding ≤ 10μM
|
TYK2-1-E |
Tyrosine-protein Kinase TYK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
56 |
0.29 |
Binding ≤ 10μM
|
TYRO3-1-E |
Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
49 |
0.29 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.33 |
Binding ≤ 10μM
|
ULK3-1-E |
Serine/threonine-protein Kinase ULK3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3 |
0.34 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
14 |
0.31 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
88 |
0.28 |
Binding ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
14 |
0.31 |
Binding ≤ 10μM
|
WEE1-1-E |
Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.23 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
52 |
0.29 |
Binding ≤ 10μM
|
ZAP70-1-E |
Tyrosine-protein Kinase ZAP-70 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
53 |
0.29 |
Binding ≤ 10μM
|
AKT1-1-E |
Serine/threonine-protein Kinase AKT (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
460 |
0.25 |
Functional ≤ 10μM
|
KPCB-1-E |
Protein Kinase C Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
77 |
0.28 |
Functional ≤ 10μM
|
Z104294-1-O |
Cyclin-dependent Kinase 5/CDK5 Activator 1 (cluster #1 Of 2), Other |
Other |
10 |
0.32 |
Binding ≤ 10μM
|
Z104295-1-O |
Cyclin-dependent Kinase 4/cyclin D1 (cluster #1 Of 2), Other |
Other |
59 |
0.29 |
Binding ≤ 10μM
|
Z100081-2-O |
PBMC (Peripheral Blood Mononuclear Cells) (cluster #2 Of 4), Other |
Other |
16 |
0.31 |
Functional ≤ 10μM
|
Z100201-1-O |
Splenocytes (Spleen Cells) (cluster #1 Of 1), Other |
Other |
400 |
0.26 |
Functional ≤ 10μM |
Z50425-3-O |
Plasmodium Falciparum (cluster #3 Of 22), Other |
Other |
190 |
0.27 |
Functional ≤ 10μM
|
Z50512-1-O |
Cavia Porcellus (cluster #1 Of 7), Other |
Other |
7500 |
0.20 |
Functional ≤ 10μM |
Z80120-1-O |
DLD-1 (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other |
Other |
9 |
0.32 |
Functional ≤ 10μM
|
Z80166-1-O |
HT-29 (Colon Adenocarcinoma Cells) (cluster #1 Of 12), Other |
Other |
3 |
0.34 |
Functional ≤ 10μM |
Z80211-1-O |
LoVo (Colon Adenocarcinoma Cells) (cluster #1 Of 5), Other |
Other |
1 |
0.36 |
Functional ≤ 10μM
|
Z80224-1-O |
MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other |
Other |
50 |
0.29 |
Functional ≤ 10μM
|
Z80800-1-O |
MIA PaCa-2 (Pancreatic Carcinoma Cells) (cluster #1 Of 2), Other |
Other |
370 |
0.26 |
Functional ≤ 10μM
|
Z80928-1-O |
HCT-116 (Colon Carcinoma Cells) (cluster #1 Of 9), Other |
Other |
6 |
0.33 |
Functional ≤ 10μM
|
Z80936-1-O |
HEK293 (Embryonic Kidney Fibroblasts) (cluster #1 Of 4), Other |
Other |
77 |
0.28 |
Functional ≤ 10μM
|
Z81057-1-O |
HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other |
Other |
4 |
0.34 |
Functional ≤ 10μM
|
Z81072-1-O |
Jurkat (Acute Leukemic T-cells) (cluster #1 Of 10), Other |
Other |
71 |
0.29 |
Functional ≤ 10μM
|
Z81247-1-O |
HeLa (Cervical Adenocarcinoma Cells) (cluster #1 Of 9), Other |
Other |
0 |
0.00 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
3.89 |
8.49 |
-39.52 |
3 |
7 |
1 |
74 |
467.549 |
2 |
↓
|
Hi
High (pH 8-9.5)
|
3.89 |
8.85 |
-16.32 |
2 |
7 |
0 |
69 |
466.541 |
2 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 17 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.29 |
Binding ≤ 10μM
|
ALK-1-E |
ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.29 |
Binding ≤ 10μM
|
AURKA-2-E |
Serine/threonine-protein Kinase Aurora-A (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
760 |
0.31 |
Binding ≤ 10μM |
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
390 |
0.32 |
Binding ≤ 10μM
|
AURKC-2-E |
Serine/threonine-protein Kinase Aurora-C (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
71 |
0.36 |
Binding ≤ 10μM
|
BMPR2-1-E |
Bone Morphogenetic Protein Receptor Type-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7800 |
0.26 |
Binding ≤ 10μM
|
CD11A-1-E |
PITSLRE Serine/threonine-protein Kinase CDC2L2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.30 |
Binding ≤ 10μM
|
CD11B-1-E |
PITSLRE Serine/threonine-protein Kinase CDC2L1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.29 |
Binding ≤ 10μM
|
CDK1-3-E |
Cyclin-dependent Kinase 1 (cluster #3 Of 4), Eukaryotic |
Eukaryotes |
9800 |
0.25 |
Binding ≤ 10μM
|
CDK19-1-E |
Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
74 |
0.36 |
Binding ≤ 10μM
|
CDK7-1-E |
Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2900 |
0.28 |
Binding ≤ 10μM
|
CDK8-1-E |
Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
95 |
0.35 |
Binding ≤ 10μM
|
CDK9-1-E |
Cyclin-dependent Kinase 9 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3000 |
0.28 |
Binding ≤ 10μM
|
CLK1-2-E |
Dual Specificty Protein Kinase CLK1 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
8900 |
0.25 |
Binding ≤ 10μM
|
CLK4-2-E |
Dual Specificity Protein Kinase CLK4 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
1600 |
0.29 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.43 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
58 |
0.36 |
Binding ≤ 10μM
|
DDR2-1-E |
Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3800 |
0.27 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
6500 |
0.26 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.27 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.32 |
Binding ≤ 10μM
|
EPHB3-1-E |
Ephrin Type-B Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.29 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.29 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.40 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
400 |
0.32 |
Binding ≤ 10μM
|
INSRR-1-E |
Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3900 |
0.27 |
Binding ≤ 10μM
|
KAPCA-1-E |
CAMP-dependent Protein Kinase Alpha-catalytic Subunit (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
6900 |
0.26 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
81 |
0.35 |
Binding ≤ 10μM
|
KS6A4-1-E |
Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7200 |
0.26 |
Binding ≤ 10μM
|
KS6A5-1-E |
Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1200 |
0.30 |
Binding ≤ 10μM
|
LATS2-1-E |
Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.29 |
Binding ≤ 10μM
|
LIMK2-1-E |
LIM Domain Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4700 |
0.27 |
Binding ≤ 10μM
|
LTK-1-E |
Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
550 |
0.31 |
Binding ≤ 10μM
|
M4K1-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
830 |
0.30 |
Binding ≤ 10μM
|
M4K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3200 |
0.27 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
910 |
0.30 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
870 |
0.30 |
Binding ≤ 10μM
|
MET-1-E |
Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.29 |
Binding ≤ 10μM
|
MK09-1-E |
C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
240 |
0.33 |
Binding ≤ 10μM
|
MK15-1-E |
Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2800 |
0.28 |
Binding ≤ 10μM
|
MKNK1-1-E |
MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4900 |
0.27 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
270 |
0.33 |
Binding ≤ 10μM
|
MUSK-1-E |
Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
10 |
0.40 |
Binding ≤ 10μM
|
NTRK1-1-E |
Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.28 |
Binding ≤ 10μM
|
NTRK2-1-E |
Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.30 |
Binding ≤ 10μM
|
NTRK3-1-E |
NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
210 |
0.33 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
4 |
0.42 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
66 |
0.36 |
Binding ≤ 10μM
|
PLK3-1-E |
Serine/threonine-protein Kinase PLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8500 |
0.25 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.29 |
Binding ≤ 10μM
|
RIPK1-1-E |
Receptor-interacting Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2800 |
0.28 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
450 |
0.32 |
Binding ≤ 10μM
|
ST32B-1-E |
Serine/threonine-protein Kinase 32B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.33 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
460 |
0.32 |
Binding ≤ 10μM
|
STK3-1-E |
Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1500 |
0.29 |
Binding ≤ 10μM
|
STK33-1-E |
Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3800 |
0.27 |
Binding ≤ 10μM
|
STK4-2-E |
Serine/threonine-protein Kinase MST1 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
1400 |
0.29 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.35 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
450 |
0.32 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
340 |
0.32 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.40 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
8 |
0.40 |
Binding ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
190 |
0.34 |
Binding ≤ 10μM
|
VGFR2-2-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
4 |
0.42 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
4.73 |
7.88 |
-12.09 |
5 |
6 |
0 |
96 |
375.407 |
3 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 31 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
AAPK1-1-E |
AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
10000 |
0.23 |
Binding ≤ 10μM
|
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
94 |
0.33 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
69 |
0.33 |
Binding ≤ 10μM
|
ACVL1-1-E |
Serine/threonine-protein Kinase Receptor R3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
470 |
0.30 |
Binding ≤ 10μM
|
ACVR1-1-E |
Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
150 |
0.32 |
Binding ≤ 10μM
|
ADCK3-1-E |
Chaperone Activity Of Bc1 Complex-like, Mitochondrial (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.25 |
Binding ≤ 10μM
|
ADCK4-1-E |
Uncharacterized AarF Domain-containing Protein Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.27 |
Binding ≤ 10μM
|
ALK-1-E |
ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.26 |
Binding ≤ 10μM
|
AURKC-1-E |
Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1500 |
0.27 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
66 |
0.34 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.28 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3700 |
0.25 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1800 |
0.27 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
11 |
0.37 |
Binding ≤ 10μM
|
DDR2-1-E |
Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
320 |
0.30 |
Binding ≤ 10μM
|
EGFR-3-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #3 Of 4), Eukaryotic |
Eukaryotes |
10 |
0.37 |
Binding ≤ 10μM
|
EGFR-3-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #3 Of 4), Eukaryotic |
Eukaryotes |
500 |
0.29 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
230 |
0.31 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.27 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2000 |
0.27 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4300 |
0.25 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
310 |
0.30 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
65 |
0.34 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3400 |
0.26 |
Binding ≤ 10μM
|
EPHA8-1-E |
Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
91 |
0.33 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
540 |
0.29 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
440 |
0.30 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
520 |
0.29 |
Binding ≤ 10μM
|
ERBB2-2-E |
Receptor Protein-tyrosine Kinase ErbB-2 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
2600 |
0.26 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
560 |
0.29 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3600 |
0.25 |
Binding ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5500 |
0.25 |
Binding ≤ 10μM
|
FGFR3-1-E |
Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6900 |
0.24 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
270 |
0.31 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
850 |
0.28 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
480 |
0.29 |
Binding ≤ 10μM
|
FYN-1-E |
Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
5700 |
0.24 |
Binding ≤ 10μM
|
GAK-1-E |
Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
86 |
0.33 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4200 |
0.25 |
Binding ≤ 10μM
|
KC1E-1-E |
Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3000 |
0.26 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
560 |
0.29 |
Binding ≤ 10μM
|
KS6A1-1-E |
Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
400 |
0.30 |
Binding ≤ 10μM
|
KS6A6-1-E |
Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
240 |
0.31 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
61 |
0.34 |
Binding ≤ 10μM
|
LTK-1-E |
Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
550 |
0.29 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
710 |
0.29 |
Binding ≤ 10μM
|
M3K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4800 |
0.25 |
Binding ≤ 10μM
|
M4K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.27 |
Binding ≤ 10μM
|
M4K4-2-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
1400 |
0.27 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
510 |
0.29 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.27 |
Binding ≤ 10μM
|
MET-1-E |
Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5700 |
0.24 |
Binding ≤ 10μM
|
MK06-1-E |
Mitogen-activated Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.27 |
Binding ≤ 10μM
|
MKNK1-1-E |
MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
360 |
0.30 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3400 |
0.26 |
Binding ≤ 10μM
|
MLTK-1-E |
Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5100 |
0.25 |
Binding ≤ 10μM
|
MP2K1-3-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #3 Of 4), Eukaryotic |
Eukaryotes |
1800 |
0.27 |
Binding ≤ 10μM
|
MP2K2-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.28 |
Binding ≤ 10μM
|
MRCKA-1-E |
Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2600 |
0.26 |
Binding ≤ 10μM
|
MRCKB-1-E |
Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2500 |
0.26 |
Binding ≤ 10μM
|
MRCKG-1-E |
Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.26 |
Binding ≤ 10μM
|
PGFRA-2-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
230 |
0.31 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
88 |
0.33 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.28 |
Binding ≤ 10μM
|
PHKG1-1-E |
Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
7100 |
0.24 |
Binding ≤ 10μM
|
PHKG2-1-E |
Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9500 |
0.23 |
Binding ≤ 10μM
|
PLK4-1-E |
Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
620 |
0.29 |
Binding ≤ 10μM
|
PTK6-1-E |
Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
33 |
0.35 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
97 |
0.33 |
Binding ≤ 10μM
|
RIPK2-1-E |
Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.39 |
Binding ≤ 10μM
|
SIK1-1-E |
Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.27 |
Binding ≤ 10μM
|
SIK2-1-E |
Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
430 |
0.30 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
96 |
0.33 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
70 |
0.33 |
Binding ≤ 10μM
|
SRMS-1-E |
Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.27 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
81 |
0.33 |
Binding ≤ 10μM
|
STK33-1-E |
Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.27 |
Binding ≤ 10μM
|
TBA1A-1-E |
Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
480 |
0.29 |
Binding ≤ 10μM
|
TESK1-1-E |
Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3700 |
0.25 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.27 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2500 |
0.26 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3600 |
0.25 |
Binding ≤ 10μM
|
TNI3K-1-E |
Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2800 |
0.26 |
Binding ≤ 10μM
|
TNIK-1-E |
TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3900 |
0.25 |
Binding ≤ 10μM
|
TXK-1-E |
Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3700 |
0.25 |
Binding ≤ 10μM
|
TYRO3-1-E |
Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
93 |
0.33 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
250 |
0.31 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
260 |
0.31 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.27 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9 |
0.38 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
40 |
0.35 |
Binding ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
300 |
0.30 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
280 |
0.31 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
170 |
0.32 |
Functional ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.28 |
Functional ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.28 |
Functional ≤ 10μM
|
FGFR3-1-E |
Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.28 |
Functional ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
60 |
0.34 |
Functional ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
400 |
0.30 |
Functional ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
60 |
0.34 |
Functional ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
400 |
0.30 |
Functional ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
60 |
0.34 |
Functional ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
400 |
0.30 |
Functional ≤ 10μM
|
Z100768-1-O |
TPC1 (Papillary Thyroid Carinoma Cells) (cluster #1 Of 1), Other |
Other |
116 |
0.32 |
Functional ≤ 10μM
|
Z80166-1-O |
HT-29 (Colon Adenocarcinoma Cells) (cluster #1 Of 12), Other |
Other |
4200 |
0.25 |
Functional ≤ 10μM
|
Z81057-1-O |
HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other |
Other |
60 |
0.34 |
Functional ≤ 10μM
|
Z81057-1-O |
HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other |
Other |
400 |
0.30 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
4.98 |
13.02 |
-39.96 |
2 |
6 |
1 |
61 |
476.37 |
6 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ADCK4-1-E |
Uncharacterized AarF Domain-containing Protein Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
129 |
0.39 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.50 |
Binding ≤ 10μM
|
BMX-1-E |
Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
36 |
0.42 |
Binding ≤ 10μM
|
BTK-1-E |
Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.45 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
28 |
0.42 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.46 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.45 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5 |
0.46 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.48 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
20 |
0.43 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.46 |
Binding ≤ 10μM
|
EPHB3-1-E |
Ephrin Type-B Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
81 |
0.40 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
FYN-1-E |
Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
0 |
0.00 |
Binding ≤ 10μM
|
KSYK-1-E |
Tyrosine-protein Kinase SYK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
26 |
0.42 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
13 |
0.44 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3 |
0.48 |
Binding ≤ 10μM
|
PTK6-1-E |
Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.49 |
Binding ≤ 10μM
|
TXK-1-E |
Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2 |
0.49 |
Binding ≤ 10μM
|
TYRO3-1-E |
Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
264 |
0.37 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1 |
0.50 |
Binding ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
3.13 |
4.7 |
-17.34 |
5 |
7 |
0 |
113 |
335.367 |
5 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 1 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
820 |
0.25 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3300 |
0.23 |
Binding ≤ 10μM
|
AURKA-1-E |
Serine/threonine-protein Kinase Aurora-A (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
4 |
0.35 |
Binding ≤ 10μM
|
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9 |
0.33 |
Binding ≤ 10μM
|
AURKC-1-E |
Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
26 |
0.31 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
68 |
0.30 |
Binding ≤ 10μM
|
BMX-1-E |
Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.23 |
Binding ≤ 10μM
|
BTK-1-E |
Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4200 |
0.22 |
Binding ≤ 10μM
|
CLK2-1-E |
Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3200 |
0.23 |
Binding ≤ 10μM
|
CLK3-1-E |
Dual Specificity Protein Kinase CLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2300 |
0.23 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9000 |
0.21 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4200 |
0.22 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
6400 |
0.21 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1800 |
0.24 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
370 |
0.26 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2100 |
0.23 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
420 |
0.26 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.24 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
580 |
0.26 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.25 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.27 |
Binding ≤ 10μM
|
EPHB3-1-E |
Ephrin Type-B Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3500 |
0.22 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
560 |
0.26 |
Binding ≤ 10μM
|
FAK2-1-E |
Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2000 |
0.23 |
Binding ≤ 10μM
|
FER-1-E |
Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4400 |
0.22 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.23 |
Binding ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.24 |
Binding ≤ 10μM
|
FGFR3-1-E |
Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.24 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
220 |
0.27 |
Binding ≤ 10μM
|
FYN-1-E |
Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
1300 |
0.24 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.24 |
Binding ≤ 10μM
|
IRAK3-1-E |
Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.24 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
590 |
0.26 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.24 |
Binding ≤ 10μM
|
MAPK5-1-E |
MAP Kinase-activated Protein Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.33 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
730 |
0.25 |
Binding ≤ 10μM
|
PLK4-1-E |
Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
410 |
0.26 |
Binding ≤ 10μM
|
ROS1-1-E |
Proto-oncogene Tyrosine-protein Kinase ROS (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.23 |
Binding ≤ 10μM
|
SIK1-1-E |
Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.24 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
800 |
0.25 |
Binding ≤ 10μM
|
ST17A-1-E |
Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
190 |
0.28 |
Binding ≤ 10μM
|
ST17B-1-E |
Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8 |
0.33 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3700 |
0.22 |
Binding ≤ 10μM
|
TEC-1-E |
Tyrosine-protein Kinase TEC (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
730 |
0.25 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.24 |
Binding ≤ 10μM
|
TIE2-1-E |
Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
300 |
0.27 |
Binding ≤ 10μM
|
TNK1-1-E |
Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.23 |
Binding ≤ 10μM
|
TYRO3-1-E |
Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.23 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
440 |
0.26 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.25 |
Binding ≤ 10μM
|
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3100 |
0.23 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
260 |
0.27 |
Binding ≤ 10μM
|
Z80166-1-O |
HT-29 (Colon Adenocarcinoma Cells) (cluster #1 Of 12), Other |
Other |
150 |
0.28 |
Functional ≤ 10μM
|
Z80224-1-O |
MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other |
Other |
670 |
0.25 |
Functional ≤ 10μM
|
Z80390-1-O |
PC-3 (Prostate Carcinoma Cells) (cluster #1 Of 10), Other |
Other |
790 |
0.25 |
Functional ≤ 10μM
|
Z80493-1-O |
SK-OV-3 (Ovarian Carcinoma Cells) (cluster #1 Of 6), Other |
Other |
530 |
0.26 |
Functional ≤ 10μM
|
Z80526-1-O |
SW480 (Colon Adenocarcinoma Cells) (cluster #1 Of 6), Other |
Other |
860 |
0.25 |
Functional ≤ 10μM
|
Z80928-3-O |
HCT-116 (Colon Carcinoma Cells) (cluster #3 Of 9), Other |
Other |
180 |
0.28 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
5.27 |
12.65 |
-57.45 |
1 |
6 |
-1 |
90 |
475.862 |
4 |
↓
|
|
|
Analogs
Draw
Identity
99%
90%
80%
70%
Vendors
And 23 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
730 |
0.25 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
870 |
0.25 |
Binding ≤ 10μM
|
ACVR1-1-E |
Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.24 |
Binding ≤ 10μM
|
ADCK3-1-E |
Chaperone Activity Of Bc1 Complex-like, Mitochondrial (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.24 |
Binding ≤ 10μM
|
ADCK4-1-E |
Uncharacterized AarF Domain-containing Protein Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3400 |
0.23 |
Binding ≤ 10μM
|
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
4200 |
0.22 |
Binding ≤ 10μM
|
AURKC-1-E |
Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.22 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
50 |
0.30 |
Binding ≤ 10μM
|
BMP2K-1-E |
BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3800 |
0.22 |
Binding ≤ 10μM
|
BMX-1-E |
Tyrosine-protein Kinase BMX (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
62 |
0.30 |
Binding ≤ 10μM
|
BTK-1-E |
Tyrosine-protein Kinase BTK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
750 |
0.25 |
Binding ≤ 10μM
|
CSK-1-E |
Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6100 |
0.21 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.24 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
400 |
0.26 |
Binding ≤ 10μM
|
EGFR-3-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #3 Of 4), Eukaryotic |
Eukaryotes |
7 |
0.34 |
Binding ≤ 10μM
|
EPHA1-1-E |
Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2500 |
0.23 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
650 |
0.25 |
Binding ≤ 10μM
|
EPHA4-1-E |
Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3600 |
0.22 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.27 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
72 |
0.29 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.24 |
Binding ≤ 10μM
|
EPHA8-1-E |
Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
790 |
0.25 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.24 |
Binding ≤ 10μM
|
EPHB2-1-E |
Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2700 |
0.23 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5000 |
0.22 |
Binding ≤ 10μM
|
ERBB2-2-E |
Receptor Protein-tyrosine Kinase ErbB-2 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
9 |
0.33 |
Binding ≤ 10μM
|
ERBB4-1-E |
Receptor Protein-tyrosine Kinase ErbB-4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
31 |
0.31 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2800 |
0.23 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
730 |
0.25 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8100 |
0.21 |
Binding ≤ 10μM
|
GAK-1-E |
Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
44 |
0.30 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5700 |
0.22 |
Binding ≤ 10μM
|
IRAK3-1-E |
Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3000 |
0.23 |
Binding ≤ 10μM
|
ITK-1-E |
Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5650 |
0.22 |
Binding ≤ 10μM
|
JAK3-1-E |
Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
630 |
0.26 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7900 |
0.21 |
Binding ≤ 10μM
|
KS6A1-1-E |
Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6200 |
0.21 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
560 |
0.26 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
810 |
0.25 |
Binding ≤ 10μM
|
M3K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8400 |
0.21 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2600 |
0.23 |
Binding ≤ 10μM
|
MET-1-E |
Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5600 |
0.22 |
Binding ≤ 10μM
|
MK06-1-E |
Mitogen-activated Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.24 |
Binding ≤ 10μM
|
MK09-1-E |
C-Jun N-terminal Kinase 2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1100 |
0.25 |
Binding ≤ 10μM
|
MK10-1-E |
C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5500 |
0.22 |
Binding ≤ 10μM
|
MKNK1-1-E |
MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
260 |
0.27 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1800 |
0.24 |
Binding ≤ 10μM
|
MLTK-1-E |
Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.24 |
Binding ≤ 10μM
|
MP2K1-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
1800 |
0.24 |
Binding ≤ 10μM
|
MP2K2-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.24 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5200 |
0.22 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7500 |
0.21 |
Binding ≤ 10μM
|
PTK6-1-E |
Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3800 |
0.22 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
840 |
0.25 |
Binding ≤ 10μM
|
RIPK2-1-E |
Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.27 |
Binding ≤ 10μM
|
SIK2-1-E |
Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4900 |
0.22 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
440 |
0.26 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
760 |
0.25 |
Binding ≤ 10μM
|
SRMS-1-E |
Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6700 |
0.21 |
Binding ≤ 10μM
|
ST17A-1-E |
Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3800 |
0.22 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
430 |
0.26 |
Binding ≤ 10μM
|
STK36-1-E |
Serine/threonine-protein Kinase 36 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.22 |
Binding ≤ 10μM
|
TBA1A-1-E |
Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
29 |
0.31 |
Binding ≤ 10μM
|
TEC-1-E |
Tyrosine-protein Kinase TEC (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1500 |
0.24 |
Binding ≤ 10μM
|
TESK1-1-E |
Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3200 |
0.23 |
Binding ≤ 10μM
|
TGFR1-1-E |
TGF-beta Receptor Type I (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9600 |
0.21 |
Binding ≤ 10μM
|
TGFR2-1-E |
TGF-beta Receptor Type II (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
800 |
0.25 |
Binding ≤ 10μM
|
TIE1-1-E |
Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.23 |
Binding ≤ 10μM
|
TNI3K-1-E |
Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5600 |
0.22 |
Binding ≤ 10μM
|
TXK-1-E |
Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
700 |
0.25 |
Binding ≤ 10μM
|
TYRO3-1-E |
Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1000 |
0.25 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5700 |
0.22 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2500 |
0.23 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2 |
0.36 |
Functional ≤ 10μM
|
ERBB2-2-E |
Receptor Protein-tyrosine Kinase ErbB-2 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
7 |
0.34 |
Functional ≤ 10μM
|
Z80961-1-O |
HN5 (Squamous Cell Carcinoma) (cluster #1 Of 1), Other |
Other |
50 |
0.30 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
4.35 |
8.5 |
-12.22 |
2 |
8 |
0 |
89 |
485.947 |
9 |
↓
|
|
|
Analogs
-
29416077
-
-
18825325
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 5 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
AAK1-1-E |
Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5300 |
0.26 |
Binding ≤ 10μM
|
AAPK1-1-E |
AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6600 |
0.26 |
Binding ≤ 10μM
|
ACVR1-1-E |
Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.29 |
Binding ≤ 10μM
|
ALK-1-E |
ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
670 |
0.31 |
Binding ≤ 10μM
|
AVR2B-1-E |
Activin Receptor Type-2B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.28 |
Binding ≤ 10μM
|
CCNA1-1-E |
Cyclin A1 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
70 |
0.36 |
Binding ≤ 10μM
|
CCNA2-1-E |
Cyclin A2 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
70 |
0.36 |
Binding ≤ 10μM
|
CCNB-1-E |
G2/mitotic-specific Cyclin B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
400 |
0.32 |
Binding ≤ 10μM |
CCNB1-1-E |
G2/mitotic-specific Cyclin B1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
520 |
0.31 |
Binding ≤ 10μM
|
CCNB2-1-E |
G2/mitotic-specific Cyclin B2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
520 |
0.31 |
Binding ≤ 10μM
|
CCNB3-1-E |
G2/mitotic-specific Cyclin B3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
520 |
0.31 |
Binding ≤ 10μM
|
CCND1-1-E |
G1/S-specific Cyclin D1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.35 |
Binding ≤ 10μM
|
CCND2-1-E |
G1/S-specific Cyclin D2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.35 |
Binding ≤ 10μM
|
CCND3-1-E |
G1/S-specific Cyclin D3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.35 |
Binding ≤ 10μM
|
CCNE1-1-E |
G1/S-specific Cyclin E1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
960 |
0.30 |
Binding ≤ 10μM
|
CCNE2-1-E |
G1/S-specific Cyclin E2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
960 |
0.30 |
Binding ≤ 10μM
|
CCNH-1-E |
Cyclin H (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
400 |
0.32 |
Binding ≤ 10μM
|
CDK1-1-E |
Cyclin-dependent Kinase 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
520 |
0.31 |
Binding ≤ 10μM
|
CDK14-1-E |
Serine/threonine-protein Kinase PFTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.35 |
Binding ≤ 10μM
|
CDK16-1-E |
Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
440 |
0.32 |
Binding ≤ 10μM
|
CDK17-1-E |
Serine/threonine-protein Kinase PCTAIRE-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
480 |
0.32 |
Binding ≤ 10μM
|
CDK18-1-E |
Serine/threonine-protein Kinase PCTAIRE-3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.30 |
Binding ≤ 10μM
|
CDK19-1-E |
Cell Division Cycle 2-like Protein Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
57 |
0.36 |
Binding ≤ 10μM
|
CDK2-1-E |
Cyclin-dependent Kinase 2 (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
960 |
0.30 |
Binding ≤ 10μM
|
CDK3-1-E |
Cyclin-dependent Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
410 |
0.32 |
Binding ≤ 10μM
|
CDK4-2-E |
Cyclin-dependent Kinase 4 (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
100 |
0.35 |
Binding ≤ 10μM
|
CDK5-1-E |
Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
43 |
0.37 |
Binding ≤ 10μM
|
CDK6-1-E |
Cyclin-dependent Kinase 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
80 |
0.35 |
Binding ≤ 10μM
|
CDK7-1-E |
Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
875 |
0.30 |
Binding ≤ 10μM
|
CDK8-1-E |
Cell Division Protein Kinase 8 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
120 |
0.35 |
Binding ≤ 10μM
|
CDK9-1-E |
Cyclin-dependent Kinase 9 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.41 |
Binding ≤ 10μM
|
CLK1-1-E |
Dual Specificty Protein Kinase CLK1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2200 |
0.28 |
Binding ≤ 10μM
|
CLK2-1-E |
Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2200 |
0.28 |
Binding ≤ 10μM
|
CLK3-1-E |
Dual Specificity Protein Kinase CLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1600 |
0.29 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2800 |
0.28 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.35 |
Binding ≤ 10μM
|
DCLK1-1-E |
Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.28 |
Binding ≤ 10μM
|
DCLK3-1-E |
Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.30 |
Binding ≤ 10μM
|
DMPK-1-E |
Myotonin-protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
650 |
0.31 |
Binding ≤ 10μM
|
DYR1B-1-E |
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
84 |
0.35 |
Binding ≤ 10μM
|
E2AK2-1-E |
Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5200 |
0.26 |
Binding ≤ 10μM
|
EGFR-2-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
7600 |
0.26 |
Binding ≤ 10μM
|
EPHA2-1-E |
Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2500 |
0.28 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3300 |
0.27 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4000 |
0.27 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.28 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6500 |
0.26 |
Binding ≤ 10μM
|
GAK-1-E |
Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
370 |
0.32 |
Binding ≤ 10μM
|
GSK3A-1-E |
Glycogen Synthase Kinase-3 Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
1300 |
0.29 |
Binding ≤ 10μM
|
GSK3B-7-E |
Glycogen Synthase Kinase-3 Beta (cluster #7 Of 7), Eukaryotic |
Eukaryotes |
730 |
0.31 |
Binding ≤ 10μM
|
IKKE-1-E |
Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.28 |
Binding ≤ 10μM
|
KCC2A-1-E |
CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.29 |
Binding ≤ 10μM
|
KCC2B-1-E |
CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2600 |
0.28 |
Binding ≤ 10μM
|
KCC4-1-E |
CaM Kinase IV (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3200 |
0.27 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4600 |
0.27 |
Binding ≤ 10μM
|
KKCC1-1-E |
CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
79 |
0.36 |
Binding ≤ 10μM
|
KKCC2-1-E |
CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
430 |
0.32 |
Binding ≤ 10μM
|
KPCA-1-E |
Protein Kinase C Alpha (cluster #1 Of 6), Eukaryotic |
Eukaryotes |
2800 |
0.28 |
Binding ≤ 10μM
|
KPCB-1-E |
Protein Kinase C Beta (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
10000 |
0.25 |
Binding ≤ 10μM
|
KPCD-1-E |
Protein Kinase C Delta (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
890 |
0.30 |
Binding ≤ 10μM
|
KPCD1-1-E |
Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
520 |
0.31 |
Binding ≤ 10μM
|
KPCD2-1-E |
Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.30 |
Binding ≤ 10μM
|
KPCD3-1-E |
Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
170 |
0.34 |
Binding ≤ 10μM
|
KPCE-1-E |
Protein Kinase C Epsilon (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
480 |
0.32 |
Binding ≤ 10μM
|
KPCG-1-E |
Protein Kinase C Gamma (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
10000 |
0.25 |
Binding ≤ 10μM
|
KPCI-1-E |
Protein Kinase C Iota (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
10000 |
0.25 |
Binding ≤ 10μM
|
KPCL-2-E |
Protein Kinase C Eta (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
350 |
0.32 |
Binding ≤ 10μM
|
KPCT-1-E |
Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
350 |
0.32 |
Binding ≤ 10μM
|
KPCZ-1-E |
Protein Kinase C Zeta (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
10000 |
0.25 |
Binding ≤ 10μM
|
KS6A1-1-E |
Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
720 |
0.31 |
Binding ≤ 10μM
|
KS6A2-1-E |
Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1600 |
0.29 |
Binding ≤ 10μM
|
KS6A4-1-E |
Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.29 |
Binding ≤ 10μM
|
KS6A5-1-E |
Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
2000 |
0.28 |
Binding ≤ 10μM
|
KS6A6-1-E |
Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
800 |
0.30 |
Binding ≤ 10μM
|
LTK-1-E |
Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.28 |
Binding ≤ 10μM
|
M3K10-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5200 |
0.26 |
Binding ≤ 10μM
|
M3K9-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5700 |
0.26 |
Binding ≤ 10μM
|
M4K1-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3300 |
0.27 |
Binding ≤ 10μM
|
M4K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.27 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6800 |
0.26 |
Binding ≤ 10μM
|
MK07-1-E |
Mitogen-activated Protein Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
620 |
0.31 |
Binding ≤ 10μM
|
MK10-1-E |
C-Jun N-terminal Kinase 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5500 |
0.26 |
Binding ≤ 10μM
|
MK15-1-E |
Mitogen-activated Protein Kinase 15 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.32 |
Binding ≤ 10μM
|
MKNK2-1-E |
MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3200 |
0.27 |
Binding ≤ 10μM
|
MRCKA-1-E |
Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9500 |
0.25 |
Binding ≤ 10μM
|
MRCKB-1-E |
Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3300 |
0.27 |
Binding ≤ 10μM
|
NUAK2-1-E |
NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.29 |
Binding ≤ 10μM
|
PHKG1-1-E |
Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2200 |
0.28 |
Binding ≤ 10μM
|
PHKG2-1-E |
Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2900 |
0.28 |
Binding ≤ 10μM
|
PIM1-1-E |
Serine/threonine-protein Kinase PIM1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
560 |
0.31 |
Binding ≤ 10μM
|
PIM2-1-E |
Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
770 |
0.31 |
Binding ≤ 10μM
|
PIM3-1-E |
Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
600 |
0.31 |
Binding ≤ 10μM
|
PKN1-1-E |
Protein Kinase N1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3500 |
0.27 |
Binding ≤ 10μM
|
PLK4-1-E |
Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3100 |
0.28 |
Binding ≤ 10μM
|
PYGM-2-E |
Muscle Glycogen Phosphorylase (cluster #2 Of 4), Eukaryotic |
Eukaryotes |
1000 |
0.30 |
Binding ≤ 10μM
|
SRMS-1-E |
Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.29 |
Binding ≤ 10μM
|
ST17B-1-E |
Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5100 |
0.26 |
Binding ≤ 10μM
|
STK3-1-E |
Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9400 |
0.25 |
Binding ≤ 10μM
|
STK33-1-E |
Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.29 |
Binding ≤ 10μM
|
TGFR2-1-E |
TGF-beta Receptor Type II (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5600 |
0.26 |
Binding ≤ 10μM
|
TNI3K-1-E |
Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
55 |
0.36 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3500 |
0.27 |
Binding ≤ 10μM
|
Z104294-2-O |
Cyclin-dependent Kinase 5/CDK5 Activator 1 (cluster #2 Of 2), Other |
Other |
170 |
0.34 |
Binding ≤ 10μM
|
Z104295-1-O |
Cyclin-dependent Kinase 4/cyclin D1 (cluster #1 Of 2), Other |
Other |
90 |
0.35 |
Binding ≤ 10μM
|
Z104295-1-O |
Cyclin-dependent Kinase 4/cyclin D1 (cluster #1 Of 2), Other |
Other |
100 |
0.35 |
Binding ≤ 10μM
|
Z104296-1-O |
Cyclin-dependent Kinase 1/cyclin B1 (cluster #1 Of 2), Other |
Other |
30 |
0.38 |
Binding ≤ 10μM
|
Z100090-1-O |
ABAE (Fibroblast Cells) (cluster #1 Of 1), Other |
Other |
45 |
0.37 |
Functional ≤ 10μM
|
Z100091-1-O |
HS27 (Fibroblast Cells) (cluster #1 Of 1), Other |
Other |
51 |
0.36 |
Functional ≤ 10μM
|
Z100093-1-O |
LX-1 (Lung Carcinoma Cells) (cluster #1 Of 1), Other |
Other |
75 |
0.36 |
Functional ≤ 10μM
|
Z100094-1-O |
MLF (Lung Fibroblast Cells) (cluster #1 Of 1), Other |
Other |
72 |
0.36 |
Functional ≤ 10μM
|
Z100095-1-O |
MIP (Colon Carcinoma Cells) (cluster #1 Of 1), Other |
Other |
120 |
0.35 |
Functional ≤ 10μM
|
Z80054-1-O |
Caco-2 (Colon Adenocarcinoma Cells) (cluster #1 Of 4), Other |
Other |
86 |
0.35 |
Functional ≤ 10μM
|
Z80064-1-O |
CCRF-CEM (T-cell Leukemia) (cluster #1 Of 9), Other |
Other |
52 |
0.36 |
Functional ≤ 10μM
|
Z80156-2-O |
HL-60 (Promyeloblast Leukemia Cells) (cluster #2 Of 12), Other |
Other |
46 |
0.37 |
Functional ≤ 10μM
|
Z80186-9-O |
K562 (Erythroleukemia Cells) (cluster #9 Of 11), Other |
Other |
130 |
0.34 |
Functional ≤ 10μM
|
Z80224-1-O |
MCF7 (Breast Carcinoma Cells) (cluster #1 Of 14), Other |
Other |
66 |
0.36 |
Functional ≤ 10μM
|
Z80354-4-O |
OVCAR-3 (Ovarian Adenocarcinoma Cells) (cluster #4 Of 4), Other |
Other |
54 |
0.36 |
Functional ≤ 10μM
|
Z80390-1-O |
PC-3 (Prostate Carcinoma Cells) (cluster #1 Of 10), Other |
Other |
66 |
0.36 |
Functional ≤ 10μM
|
Z80475-1-O |
SK-BR-3 (Breast Adenocarcinoma) (cluster #1 Of 3), Other |
Other |
77 |
0.36 |
Functional ≤ 10μM
|
Z80675-1-O |
AG1523 (Fibroblast Cells) (cluster #1 Of 1), Other |
Other |
6700 |
0.26 |
Functional ≤ 10μM
|
Z80682-1-O |
A549 (Lung Carcinoma Cells) (cluster #1 Of 11), Other |
Other |
96 |
0.35 |
Functional ≤ 10μM
|
Z80852-2-O |
A-431 (Epidermoid Carcinoma Cells) (cluster #2 Of 3), Other |
Other |
75 |
0.36 |
Functional ≤ 10μM
|
Z80928-1-O |
HCT-116 (Colon Carcinoma Cells) (cluster #1 Of 9), Other |
Other |
490 |
0.32 |
Functional ≤ 10μM
|
Z81034-1-O |
A2780 (Ovarian Carcinoma Cells) (cluster #1 Of 10), Other |
Other |
78 |
0.36 |
Functional ≤ 10μM
|
Z81170-1-O |
LNCaP (Prostate Carcinoma) (cluster #1 Of 5), Other |
Other |
16 |
0.39 |
Functional ≤ 10μM
|
Z81186-1-O |
LS174T (Colon Adencocarcinoma Cells) (cluster #1 Of 2), Other |
Other |
65 |
0.36 |
Functional ≤ 10μM
|
Z81225-1-O |
M109 (Lung Carcinoma Cells) (cluster #1 Of 2), Other |
Other |
80 |
0.35 |
Functional ≤ 10μM
|
Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
3.46 |
7.04 |
-50.59 |
4 |
6 |
1 |
95 |
402.854 |
2 |
↓
|
Hi
High (pH 8-9.5)
|
3.46 |
7.74 |
-91.2 |
3 |
6 |
0 |
98 |
401.846 |
2 |
↓
|
|
|
Analogs
-
13493833
-
-
13673696
-
-
36758328
-
Draw
Identity
99%
90%
80%
70%
Vendors
And 33 More
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
AAK1-1-E |
Adaptor-associated Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
130 |
0.33 |
Binding ≤ 10μM
|
AAPK1-1-E |
AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
52 |
0.35 |
Binding ≤ 10μM
|
AAPK2-1-E |
AMP-activated Protein Kinase, Alpha-2 Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
89 |
0.34 |
Binding ≤ 10μM
|
ABL1-1-E |
Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
950 |
0.29 |
Binding ≤ 10μM
|
ABL2-1-E |
Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.29 |
Binding ≤ 10μM
|
ACK1-1-E |
Tyrosine Kinase Non-receptor Protein 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8900 |
0.24 |
Binding ≤ 10μM
|
AKT2-2-E |
Serine/threonine-protein Kinase AKT2 (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
2700 |
0.27 |
Binding ≤ 10μM
|
ALK-1-E |
ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
170 |
0.33 |
Binding ≤ 10μM
|
ANKK1-1-E |
Ankyrin Repeat And Protein Kinase Domain-containing Protein 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
310 |
0.31 |
Binding ≤ 10μM
|
AURKA-1-E |
Serine/threonine-protein Kinase Aurora-A (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
6600 |
0.25 |
Binding ≤ 10μM
|
AURKB-1-E |
Serine/threonine-protein Kinase Aurora-B (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
380 |
0.31 |
Binding ≤ 10μM
|
AURKC-1-E |
Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
310 |
0.31 |
Binding ≤ 10μM
|
BLK-1-E |
Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
65 |
0.35 |
Binding ≤ 10μM
|
BMP2K-1-E |
BMP-2-inducible Protein Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.40 |
Binding ≤ 10μM
|
BMPR2-1-E |
Bone Morphogenetic Protein Receptor Type-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.30 |
Binding ≤ 10μM
|
BRD4-1-E |
Bromodomain-containing Protein 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
500 |
0.30 |
Binding ≤ 10μM
|
BRSK1-1-E |
BR Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3500 |
0.26 |
Binding ≤ 10μM
|
BRSK2-1-E |
BR Serine/threonine-protein Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.29 |
Binding ≤ 10μM
|
CDK14-1-E |
Serine/threonine-protein Kinase PFTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
270 |
0.32 |
Binding ≤ 10μM
|
CDK16-1-E |
Serine/threonine-protein Kinase PCTAIRE-1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
150 |
0.33 |
Binding ≤ 10μM
|
CDK17-1-E |
Serine/threonine-protein Kinase PCTAIRE-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.29 |
Binding ≤ 10μM
|
CDK18-1-E |
Serine/threonine-protein Kinase PCTAIRE-3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1700 |
0.28 |
Binding ≤ 10μM
|
CDK7-1-E |
Cyclin-dependent Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.31 |
Binding ≤ 10μM
|
CDKL2-1-E |
Cyclin-dependent Kinase-like 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.29 |
Binding ≤ 10μM
|
CHK1-1-E |
Serine/threonine-protein Kinase Chk1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
300 |
0.31 |
Binding ≤ 10μM
|
CHK2-1-E |
Serine/threonine-protein Kinase Chk2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
7 |
0.39 |
Binding ≤ 10μM
|
CLK1-1-E |
Dual Specificty Protein Kinase CLK1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
22 |
0.37 |
Binding ≤ 10μM
|
CLK2-1-E |
Dual Specificity Protein Kinase CLK2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
20 |
0.37 |
Binding ≤ 10μM
|
CLK4-1-E |
Dual Specificity Protein Kinase CLK4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
80 |
0.34 |
Binding ≤ 10μM
|
CSF1R-1-E |
Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
35 |
0.36 |
Binding ≤ 10μM
|
CSK21-1-E |
Casein Kinase II Alpha (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
81 |
0.34 |
Binding ≤ 10μM
|
CSK22-1-E |
Casein Kinase II Alpha (prime) (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
370 |
0.31 |
Binding ≤ 10μM
|
CTRO-1-E |
Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3900 |
0.26 |
Binding ≤ 10μM
|
DAPK1-1-E |
Death-associated Protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
120 |
0.33 |
Binding ≤ 10μM
|
DAPK2-1-E |
Death-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
470 |
0.31 |
Binding ≤ 10μM
|
DAPK3-1-E |
Death-associated Protein Kinase 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
300 |
0.31 |
Binding ≤ 10μM
|
DCLK1-1-E |
Serine/threonine-protein Kinase DCLK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
370 |
0.31 |
Binding ≤ 10μM
|
DCLK2-1-E |
Serine/threonine-protein Kinase DCLK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2700 |
0.27 |
Binding ≤ 10μM
|
DCLK3-1-E |
Serine/threonine-protein Kinase DCLK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.34 |
Binding ≤ 10μM
|
DDR1-1-E |
Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2000 |
0.28 |
Binding ≤ 10μM
|
DLK1-1-E |
Protein Delta Homolog 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
100 |
0.34 |
Binding ≤ 10μM
|
DYR1A-3-E |
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (cluster #3 Of 3), Eukaryotic |
Eukaryotes |
200 |
0.32 |
Binding ≤ 10μM
|
DYR1B-1-E |
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2300 |
0.27 |
Binding ≤ 10μM
|
DYRK2-1-E |
Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
680 |
0.30 |
Binding ≤ 10μM
|
E2AK2-1-E |
Interferon-induced, Double-stranded RNA-activated Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
670 |
0.30 |
Binding ≤ 10μM
|
E2AK4-1-E |
Eukaryotic Translation Initiation Factor 2-alpha Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
180 |
0.33 |
Binding ≤ 10μM
|
EGFR-1-E |
Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
6800 |
0.25 |
Binding ≤ 10μM
|
EPHA3-1-E |
Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2100 |
0.27 |
Binding ≤ 10μM
|
EPHA5-1-E |
Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5900 |
0.25 |
Binding ≤ 10μM
|
EPHA6-1-E |
Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
960 |
0.29 |
Binding ≤ 10μM
|
EPHA7-1-E |
Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
710 |
0.30 |
Binding ≤ 10μM
|
EPHB1-1-E |
Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
960 |
0.29 |
Binding ≤ 10μM
|
EPHB4-1-E |
Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2200 |
0.27 |
Binding ≤ 10μM
|
EPHB6-1-E |
Ephrin Type-B Receptor 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
850 |
0.29 |
Binding ≤ 10μM
|
ERN1-1-E |
Serine/threonine-protein Kinase/endoribonuclease IRE1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
600 |
0.30 |
Binding ≤ 10μM
|
FAK1-1-E |
Focal Adhesion Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
610 |
0.30 |
Binding ≤ 10μM
|
FAK2-1-E |
Protein-tyrosine Kinase 2-beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
82 |
0.34 |
Binding ≤ 10μM
|
FER-1-E |
Tyrosine-protein Kinase FER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1400 |
0.28 |
Binding ≤ 10μM
|
FES-1-E |
Tyrosine-protein Kinase FES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
960 |
0.29 |
Binding ≤ 10μM
|
FGFR1-1-E |
Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
520 |
0.30 |
Binding ≤ 10μM
|
FGFR2-1-E |
Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
570 |
0.30 |
Binding ≤ 10μM
|
FGFR3-1-E |
Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
300 |
0.31 |
Binding ≤ 10μM
|
FGR-1-E |
Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
290 |
0.32 |
Binding ≤ 10μM
|
FLT3-1-E |
Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
10 |
0.39 |
Binding ≤ 10μM
|
FRK-1-E |
Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
530 |
0.30 |
Binding ≤ 10μM
|
FYN-1-E |
Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic |
Eukaryotes |
520 |
0.30 |
Binding ≤ 10μM
|
GAK-1-E |
Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
20 |
0.37 |
Binding ≤ 10μM
|
GRK4-1-E |
G Protein-coupled Receptor Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
140 |
0.33 |
Binding ≤ 10μM
|
GRK7-1-E |
G Protein-coupled Receptor Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
180 |
0.33 |
Binding ≤ 10μM
|
HCK-1-E |
Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
880 |
0.29 |
Binding ≤ 10μM
|
HIPK2-1-E |
Homeodomain-interacting Protein Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
31 |
0.36 |
Binding ≤ 10μM
|
HIPK3-1-E |
Homeodomain-interacting Protein Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
41 |
0.36 |
Binding ≤ 10μM
|
HIPK4-1-E |
Homeodomain-interacting Protein Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
160 |
0.33 |
Binding ≤ 10μM
|
ICK-1-E |
Serine/threonine-protein Kinase ICK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
470 |
0.31 |
Binding ≤ 10μM
|
IGF1R-1-E |
Insulin-like Growth Factor 1 Receptor (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
2600 |
0.27 |
Binding ≤ 10μM
|
IKKA-1-E |
Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
520 |
0.30 |
Binding ≤ 10μM
|
IKKE-1-E |
Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
620 |
0.30 |
Binding ≤ 10μM
|
INSR-1-E |
Insulin Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
500 |
0.30 |
Binding ≤ 10μM
|
INSRR-1-E |
Insulin Receptor-related Protein (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
430 |
0.31 |
Binding ≤ 10μM
|
IRAK1-1-E |
Interleukin-1 Receptor-associated Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
14 |
0.38 |
Binding ≤ 10μM
|
IRAK3-1-E |
Interleukin-1 Receptor-associated Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
940 |
0.29 |
Binding ≤ 10μM
|
ITK-1-E |
Tyrosine-protein Kinase ITK/TSK (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
13 |
0.38 |
Binding ≤ 10μM
|
JAK1-1-E |
Tyrosine-protein Kinase JAK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.39 |
Binding ≤ 10μM
|
JAK2-1-E |
Tyrosine-protein Kinase JAK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
940 |
0.29 |
Binding ≤ 10μM
|
JAK3-1-E |
Tyrosine-protein Kinase JAK3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1200 |
0.29 |
Binding ≤ 10μM
|
KC1A-1-E |
Casein Kinase I Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
550 |
0.30 |
Binding ≤ 10μM
|
KC1AL-1-E |
Casein Kinase I Isoform Alpha-like (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
550 |
0.30 |
Binding ≤ 10μM
|
KC1D-1-E |
Casein Kinase I Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
15 |
0.38 |
Binding ≤ 10μM
|
KC1E-1-E |
Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
13 |
0.38 |
Binding ≤ 10μM
|
KC1G1-1-E |
Casein Kinase I Gamma 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
930 |
0.29 |
Binding ≤ 10μM
|
KC1G2-1-E |
Casein Kinase I Gamma 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.34 |
Binding ≤ 10μM
|
KC1G3-1-E |
Casein Kinase I Isoform Gamma-3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
240 |
0.32 |
Binding ≤ 10μM
|
KCC1A-1-E |
CaM Kinase I Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
970 |
0.29 |
Binding ≤ 10μM
|
KCC1D-1-E |
CaM Kinase I Delta (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
510 |
0.30 |
Binding ≤ 10μM
|
KCC1G-1-E |
CaM Kinase I Gamma (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
990 |
0.29 |
Binding ≤ 10μM
|
KCC2A-1-E |
CaM Kinase II Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
80 |
0.34 |
Binding ≤ 10μM
|
KCC2B-1-E |
CaM Kinase II Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3200 |
0.27 |
Binding ≤ 10μM
|
KCC2D-1-E |
CaM Kinase II Delta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
420 |
0.31 |
Binding ≤ 10μM
|
KCC2G-1-E |
CaM Kinase II Gamma (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
760 |
0.30 |
Binding ≤ 10μM
|
KCC4-1-E |
CaM Kinase IV (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
890 |
0.29 |
Binding ≤ 10μM
|
KIT-1-E |
Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
380 |
0.31 |
Binding ≤ 10μM
|
KKCC1-1-E |
CaM-kinase Kinase Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
900 |
0.29 |
Binding ≤ 10μM
|
KKCC2-1-E |
CaM-kinase Kinase Beta (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5800 |
0.25 |
Binding ≤ 10μM
|
KPCA-1-E |
Protein Kinase C Alpha (cluster #1 Of 6), Eukaryotic |
Eukaryotes |
6000 |
0.25 |
Binding ≤ 10μM
|
KPCD1-1-E |
Protein Kinase C Mu (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
310 |
0.31 |
Binding ≤ 10μM
|
KPCD2-1-E |
Serine/threonine-protein Kinase D2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
380 |
0.31 |
Binding ≤ 10μM
|
KPCD3-1-E |
Protein Kinase C Nu (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
280 |
0.32 |
Binding ≤ 10μM
|
KPCT-1-E |
Protein Kinase C Theta (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
4300 |
0.26 |
Binding ≤ 10μM
|
KS6A1-1-E |
Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
96 |
0.34 |
Binding ≤ 10μM
|
KS6A2-1-E |
Ribosomal Protein S6 Kinase Alpha 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
8400 |
0.25 |
Binding ≤ 10μM
|
KS6A3-1-E |
Ribosomal Protein S6 Kinase Alpha 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
580 |
0.30 |
Binding ≤ 10μM
|
KS6A4-1-E |
Ribosomal Protein S6 Kinase Alpha 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
96 |
0.34 |
Binding ≤ 10μM
|
KS6A5-1-E |
Ribosomal Protein S6 Kinase Alpha 5 (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
8400 |
0.25 |
Binding ≤ 10μM
|
KS6A6-1-E |
Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.27 |
Binding ≤ 10μM
|
KS6B1-1-E |
Ribosomal Protein S6 Kinase 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
200 |
0.32 |
Binding ≤ 10μM
|
LATS1-1-E |
Serine/threonine-protein Kinase LATS1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
630 |
0.30 |
Binding ≤ 10μM
|
LATS2-1-E |
Serine/threonine-protein Kinase LATS2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
460 |
0.31 |
Binding ≤ 10μM
|
LCK-1-E |
Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
230 |
0.32 |
Binding ≤ 10μM
|
LTK-1-E |
Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1800 |
0.28 |
Binding ≤ 10μM
|
LYN-1-E |
Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
540 |
0.30 |
Binding ≤ 10μM
|
M3K11-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 11 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.28 |
Binding ≤ 10μM
|
M3K13-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 13 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
95 |
0.34 |
Binding ≤ 10μM
|
M3K15-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 15 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.28 |
Binding ≤ 10μM
|
M3K2-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
57 |
0.35 |
Binding ≤ 10μM
|
M3K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.32 |
Binding ≤ 10μM
|
M3K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3300 |
0.26 |
Binding ≤ 10μM
|
M3K7-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
93 |
0.34 |
Binding ≤ 10μM
|
M3K9-1-E |
Mitogen-activated Protein Kinase Kinase Kinase 9 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3400 |
0.26 |
Binding ≤ 10μM
|
M4K1-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
16 |
0.38 |
Binding ≤ 10μM
|
M4K3-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
180 |
0.33 |
Binding ≤ 10μM
|
M4K4-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
140 |
0.33 |
Binding ≤ 10μM
|
M4K5-1-E |
Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
77 |
0.34 |
Binding ≤ 10μM
|
MARK1-1-E |
Serine/threonine-protein Kinase MARK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1200 |
0.29 |
Binding ≤ 10μM
|
MARK2-1-E |
MAP/microtubule Affinity-regulating Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
320 |
0.31 |
Binding ≤ 10μM
|
MARK3-1-E |
Serine/threonine-protein Kinase C-TAK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
640 |
0.30 |
Binding ≤ 10μM
|
MARK4-1-E |
MAP/microtubule Affinity-regulating Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3600 |
0.26 |
Binding ≤ 10μM
|
MAST1-1-E |
Microtubule-associated Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
200 |
0.32 |
Binding ≤ 10μM
|
MELK-1-E |
Maternal Embryonic Leucine Zipper Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
350 |
0.31 |
Binding ≤ 10μM
|
MERTK-1-E |
Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
26 |
0.37 |
Binding ≤ 10μM
|
MET-1-E |
Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2000 |
0.28 |
Binding ≤ 10μM
|
MINK1-1-E |
Misshapen-like Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
29 |
0.36 |
Binding ≤ 10μM
|
MP2K1-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #1 Of 4), Eukaryotic |
Eukaryotes |
130 |
0.33 |
Binding ≤ 10μM
|
MP2K2-1-E |
Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
110 |
0.34 |
Binding ≤ 10μM
|
MST4-1-E |
Serine/threonine-protein Kinase MST4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
340 |
0.31 |
Binding ≤ 10μM
|
MUSK-1-E |
Muscle, Skeletal Receptor Tyrosine Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
490 |
0.30 |
Binding ≤ 10μM
|
MYLK-1-E |
Myosin Light Chain Kinase, Smooth Muscle (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
280 |
0.32 |
Binding ≤ 10μM
|
MYLK2-1-E |
Myosin Light Chain Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
57 |
0.35 |
Binding ≤ 10μM
|
MYLK4-1-E |
Myosin Light Chain Kinase Family Member 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
15 |
0.38 |
Binding ≤ 10μM
|
MYO3B-1-E |
Myosin-IIIB (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4500 |
0.26 |
Binding ≤ 10μM
|
NEK2-1-E |
Serine/threonine-protein Kinase NEK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
500 |
0.30 |
Binding ≤ 10μM
|
NEK7-1-E |
Serine/threonine-protein Kinase NEK7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4100 |
0.26 |
Binding ≤ 10μM
|
NIM1-1-E |
Serine/threonine-protein Kinase NIM1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
850 |
0.29 |
Binding ≤ 10μM
|
NTRK1-1-E |
Nerve Growth Factor Receptor Trk-A (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.32 |
Binding ≤ 10μM
|
NTRK2-1-E |
Neurotrophic Tyrosine Kinase Receptor Type 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
590 |
0.30 |
Binding ≤ 10μM
|
NTRK3-1-E |
NT-3 Growth Factor Receptor (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5100 |
0.26 |
Binding ≤ 10μM
|
NUAK1-1-E |
NUAK Family SNF1-like Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
48 |
0.35 |
Binding ≤ 10μM
|
NUAK2-1-E |
NUAK Family SNF1-like Kinase 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
150 |
0.33 |
Binding ≤ 10μM
|
OXSR1-1-E |
Serine/threonine-protein Kinase OSR1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
530 |
0.30 |
Binding ≤ 10μM
|
PAK3-1-E |
Serine/threonine-protein Kinase PAK 3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
16 |
0.38 |
Binding ≤ 10μM
|
PAK4-1-E |
Serine/threonine-protein Kinase PAK 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2300 |
0.27 |
Binding ≤ 10μM
|
PAK6-1-E |
Serine/threonine-protein Kinase PAK6 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.27 |
Binding ≤ 10μM
|
PAK7-1-E |
Serine/threonine-protein Kinase PAK7 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
640 |
0.30 |
Binding ≤ 10μM
|
PDPK1-1-E |
3-phosphoinositide Dependent Protein Kinase-1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
3500 |
0.26 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
1 |
0.43 |
Binding ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.39 |
Binding ≤ 10μM
|
PHKG1-1-E |
Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
70 |
0.35 |
Binding ≤ 10μM
|
PHKG2-1-E |
Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
6 |
0.40 |
Binding ≤ 10μM
|
PI42B-1-E |
Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
39 |
0.36 |
Binding ≤ 10μM
|
PI51A-1-E |
Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
5400 |
0.25 |
Binding ≤ 10μM
|
PIM2-1-E |
Serine/threonine-protein Kinase PIM2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
5000 |
0.26 |
Binding ≤ 10μM
|
PIM3-1-E |
Serine/threonine-protein Kinase PIM3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2400 |
0.27 |
Binding ≤ 10μM
|
PKN1-1-E |
Protein Kinase N1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
710 |
0.30 |
Binding ≤ 10μM
|
PKN2-1-E |
Protein Kinase N2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.28 |
Binding ≤ 10μM
|
PLK2-1-E |
Serine/threonine-protein Kinase PLK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
4700 |
0.26 |
Binding ≤ 10μM
|
PLK4-1-E |
Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
380 |
0.31 |
Binding ≤ 10μM
|
PRP4-1-E |
U4/U6 Small Nuclear Ribonucleoprotein Prp4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
390 |
0.31 |
Binding ≤ 10μM
|
RET-1-E |
Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
19 |
0.37 |
Binding ≤ 10μM
|
RIOK1-1-E |
Serine/threonine-protein Kinase RIO1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
35 |
0.36 |
Binding ≤ 10μM
|
RIOK2-1-E |
Serine/threonine-protein Kinase RIO2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
49 |
0.35 |
Binding ≤ 10μM
|
RIOK3-1-E |
Serine/threonine-protein Kinase RIO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3800 |
0.26 |
Binding ≤ 10μM
|
RIPK1-1-E |
Receptor-interacting Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
370 |
0.31 |
Binding ≤ 10μM
|
RIPK4-1-E |
Receptor-interacting Serine/threonine-protein Kinase 4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
2100 |
0.27 |
Binding ≤ 10μM
|
RK-1-E |
Rhodopsin Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
290 |
0.32 |
Binding ≤ 10μM
|
ROCK1-1-E |
Rho-associated Protein Kinase 1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
460 |
0.31 |
Binding ≤ 10μM
|
ROCK2-1-E |
Rho-associated Protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
140 |
0.33 |
Binding ≤ 10μM
|
SG110-1-E |
Putative Uncharacterized Serine/threonine-protein Kinase SgK110 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1900 |
0.28 |
Binding ≤ 10μM
|
SIK1-1-E |
Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
3200 |
0.27 |
Binding ≤ 10μM
|
SIK2-1-E |
Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
580 |
0.30 |
Binding ≤ 10μM
|
SLK-1-E |
Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
81 |
0.34 |
Binding ≤ 10μM
|
SRC-1-E |
Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic |
Eukaryotes |
400 |
0.31 |
Binding ≤ 10μM
|
SRPK1-1-E |
Serine/threonine-protein Kinase SRPK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
250 |
0.32 |
Binding ≤ 10μM
|
SRPK2-1-E |
Serine/threonine-protein Kinase SRPK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
190 |
0.32 |
Binding ≤ 10μM
|
SRPK3-1-E |
Serine/threonine-protein Kinase SRPK3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
59 |
0.35 |
Binding ≤ 10μM
|
ST17A-1-E |
Serine/threonine-protein Kinase 17A (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
21 |
0.37 |
Binding ≤ 10μM
|
ST17B-1-E |
Serine/threonine-protein Kinase 17B (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
220 |
0.32 |
Binding ≤ 10μM
|
ST38L-1-E |
Serine/threonine-protein Kinase 38-like (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
970 |
0.29 |
Binding ≤ 10μM
|
STK10-1-E |
Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
640 |
0.30 |
Binding ≤ 10μM
|
STK11-1-E |
Serine/threonine-protein Kinase 11 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
38 |
0.36 |
Binding ≤ 10μM
|
STK16-1-E |
Serine/threonine-protein Kinase 16 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
360 |
0.31 |
Binding ≤ 10μM
|
STK24-1-E |
Serine/threonine-protein Kinase 24 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
63 |
0.35 |
Binding ≤ 10μM
|
STK25-1-E |
Serine/threonine-protein Kinase 25 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
290 |
0.32 |
Binding ≤ 10μM
|
STK3-1-E |
Serine/threonine-protein Kinase MST2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
160 |
0.33 |
Binding ≤ 10μM
|
STK33-1-E |
Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
17 |
0.38 |
Binding ≤ 10μM
|
STK35-1-E |
Serine/threonine-protein Kinase 35 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1300 |
0.28 |
Binding ≤ 10μM
|
STK38-1-E |
Serine/threonine-protein Kinase 38 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
410 |
0.31 |
Binding ≤ 10μM
|
STK39-1-E |
STE20/SPS1-related Proline-alanine-rich Protein Kinase (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
140 |
0.33 |
Binding ≤ 10μM
|
STK4-1-E |
Serine/threonine-protein Kinase MST1 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
19 |
0.37 |
Binding ≤ 10μM
|
TAOK1-1-E |
Serine/threonine-protein Kinase TAO1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
890 |
0.29 |
Binding ≤ 10μM
|
TAOK3-1-E |
Serine/threonine-protein Kinase TAO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
210 |
0.32 |
Binding ≤ 10μM
|
TBK1-1-E |
Serine/threonine-protein Kinase TBK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
120 |
0.33 |
Binding ≤ 10μM
|
TLK1-1-E |
Serine/threonine-protein Kinase Tousled-like 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
740 |
0.30 |
Binding ≤ 10μM
|
TLK2-1-E |
Serine/threonine-protein Kinase Tousled-like 2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
330 |
0.31 |
Binding ≤ 10μM
|
TNIK-1-E |
TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
25 |
0.37 |
Binding ≤ 10μM
|
TNK1-1-E |
Non-receptor Tyrosine-protein Kinase TNK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
680 |
0.30 |
Binding ≤ 10μM
|
TNKS2-1-E |
Tankyrase-2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
8900 |
0.24 |
Binding ≤ 10μM
|
TSSK1-1-E |
Testis-specific Serine/threonine-protein Kinase 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
6300 |
0.25 |
Binding ≤ 10μM
|
TTK-1-E |
Dual Specificity Protein Kinase TTK (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
63 |
0.35 |
Binding ≤ 10μM
|
TYK2-1-E |
Tyrosine-protein Kinase TYK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
360 |
0.31 |
Binding ≤ 10μM
|
TYRO3-1-E |
Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
49 |
0.35 |
Binding ≤ 10μM
|
UFO-1-E |
Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
9 |
0.39 |
Binding ≤ 10μM
|
ULK1-1-E |
Serine/threonine-protein Kinase ULK1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
23 |
0.37 |
Binding ≤ 10μM
|
ULK2-1-E |
Serine/threonine-protein Kinase ULK2 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
13 |
0.38 |
Binding ≤ 10μM
|
ULK3-1-E |
Serine/threonine-protein Kinase ULK3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
42 |
0.36 |
Binding ≤ 10μM
|
VGFR1-1-E |
Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
50 |
0.35 |
Binding ≤ 10μM
|
VGFR2-1-E |
Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
98 |
0.34 |
Binding ≤ 10μM |
VGFR3-1-E |
Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
9 |
0.39 |
Binding ≤ 10μM |
WEE1-1-E |
Serine/threonine-protein Kinase WEE1 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
1100 |
0.29 |
Binding ≤ 10μM
|
YES-1-E |
Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
240 |
0.32 |
Binding ≤ 10μM
|
YSK4-1-E |
SPS1/STE20-related Protein Kinase YSK4 (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
17 |
0.38 |
Binding ≤ 10μM
|
PGFRA-1-E |
Platelet-derived Growth Factor Receptor Alpha (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
83 |
0.34 |
Functional ≤ 10μM
|
PGFRB-1-E |
Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic |
Eukaryotes |
83 |
0.34 |
Functional ≤ 10μM
|
Z100405-1-O |
MV4-11 (Myeloid Leukemia Cells) (cluster #1 Of 1), Other |
Other |
9 |
0.39 |
Functional ≤ 10μM
|
Z80101-2-O |
COLO 320DM (Colon Adenocarcinoma Cells) (cluster #2 Of 2), Other |
Other |
1 |
0.43 |
Functional ≤ 10μM
|
| |