UCSF

Matrix Metalloproteinase-2, Mouse (3 Compounds)

Swissprot:
MMP2_MOUSE
Stitch:
MMP2_MOUSE
UniProt:
P33434
ChEMBL:
CHEMBL3095
Reactome:
REACT_199000
REACT_199055
REACT_199052
REACT_243590
REACT_235886
PDB:
Mmp2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3 0 0 1
Binding ≤ 1μM 3 0 0 1

Reactome Network (5)

Reactome ID Description Species
REACT_199000 Activation of Matrix Metalloproteinases Mus musculus
REACT_199055 Collagen degradation Mus musculus
REACT_199052 Degradation of the extracellular matrix Mus musculus
REACT_243590 EPH-ephrin mediated repulsion of cells Mus musculus
REACT_235886 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l Mus musculus
Uniprot Swissprot Chembl Description Number Shared
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 3

Collagen degradation

Uniprot Swissprot Chembl Description Number Shared
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 3

Degradation of the extracellular matrix

Uniprot Swissprot Chembl Description Number Shared
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 3

EPH-ephrin mediated repulsion of cells

Uniprot Swissprot Chembl Description Number Shared
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 2,765 37 17 44
MMP2_RAT P33436 CHEMBL1075175 72 KDa Type IV Collagenase, Rat 1 0 1 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MMP11_MOUSE Q02853 CHEMBL3412 Matrix Metalloproteinase 11, Mouse 73 0 0 0
MMP12_MOUSE P34960 CHEMBL2594 Matrix Metalloproteinase 12, Mouse 16 0 0 1
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 3 0 0 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
MMP2-1-E 72 KDa Type IV Collagenase (cluster #1 Of 3), Eukaryotic 2,665 34 12 41
MMP2-2-E 72 KDa Type IV Collagenase (cluster #2 Of 3), Eukaryotic 112 8 7 5
MMP2-3-E 72 KDa Type IV Collagenase (cluster #3 Of 3), Eukaryotic 20 1 1 0
Uniprot Swissprot Chembl Description Number Shared
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 3
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 3
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 3
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 3
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 1
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 1
BMP1_HUMAN P13497 CHEMBL3898 Bone Morphogenetic Protein 1, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MMP12_MOUSE P34960 CHEMBL2594 Matrix Metalloproteinase 12, Mouse 1
MMP13_RAT P23097 CHEMBL4944 Matrix Metalloproteinase 13, Rat 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP16_HUMAN P51512 CHEMBL2200 Matrix Metalloproteinase 16, Human 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 1
MMP25_HUMAN Q9NPA2 CHEMBL1795103 Matrix Metalloproteinase-25, Human 1
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 1
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 1