UCSF

Bone Morphogenetic Protein 1, Human (348 Compounds)

Swissprot:
BMP1_HUMAN
Stitch:
BMP1_HUMAN
UniProt:
P13497
ChEMBL:
CHEMBL3898
Reactome:
REACT_150268
REACT_121139
REACT_150206
REACT_118572
PDB:
3EDG (DOCK)
3EDH (DOCK)
BMP1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 348 1 0 1
Binding ≤ 1μM 305 1 0 0

Reactome Network (4)

Reactome ID Description Species
REACT_150268 Anchoring fibril formation Homo sapiens
REACT_121139 Collagen biosynthesis and modifying enzymes Homo sapiens
REACT_150206 Crosslinking of collagen fibrils Homo sapiens
REACT_118572 Degradation of the extracellular matrix Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 1
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 4
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 4
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 1
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 4
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 13 13 5 9
BMP4_HUMAN P12644 CHEMBL5350 Bone Morphogenetic Protein 4, Human 20 2 0 1
BMPR2_HUMAN Q13873 CHEMBL5467 Bone Morphogenetic Protein Receptor Type-2, Human 7 7 2 3

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 4
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 4
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 4
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3
ADA10_HUMAN O14672 CHEMBL5028 ADAM10, Human 1
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 1
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 1
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MMP12_MOUSE P34960 CHEMBL2594 Matrix Metalloproteinase 12, Mouse 1
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 1
MMP13_RAT P23097 CHEMBL4944 Matrix Metalloproteinase 13, Rat 1
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 1
MMP16_HUMAN P51512 CHEMBL2200 Matrix Metalloproteinase 16, Human 1
MMP25_HUMAN Q9NPA2 CHEMBL1795103 Matrix Metalloproteinase-25, Human 1
MMP2_MOUSE P33434 CHEMBL3095 Matrix Metalloproteinase-2, Mouse 1
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 1
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1
MMP9_MOUSE P41245 CHEMBL2214 Matrix Metalloproteinase 9, Mouse 1
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 1
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 1
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 1
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 1