UCSF

GAR Transformylase, Human (109 Compounds)

Swissprot:
PUR2_HUMAN
Stitch:
PUR2_HUMAN
UniProt:
P22102
ChEMBL:
CHEMBL3972
Reactome:
REACT_1776
PDB:
1MEJ (DOCK)
1MEN (DOCK)
1MEO (DOCK)
1NJS (DOCK)
1RBM (DOCK)
1RBQ (DOCK)
1RBY (DOCK)
1RBZ (DOCK)
1RC0 (DOCK)
1RC1 (DOCK)
1ZLX (DOCK)
1ZLY (DOCK)
2QK4 (DOCK)
2V9Y (DOCK)
GART

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 109 3 2 6
Binding ≤ 1μM 70 2 2 6
Functional ≤ 10μM 1 0 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_1776 Purine ribonucleoside monophosphate biosynthesis Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PUR9_HUMAN P31939 CHEMBL2518 AICAR Transformylase, Human 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PUR2_MOUSE Q64737 CHEMBL3690 GAR Transformylase, Mouse 68 1 2 7
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PUR9_HUMAN P31939 CHEMBL2518 AICAR Transformylase, Human 21 6 1 0
PURA2_HUMAN P30520 CHEMBL4875 Adenylosuccinate Synthetase 2, Human 3 1 0 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
PUR2_MOUSE Q64737 CHEMBL3690 GAR Transformylase, Mouse 20
FOLR1_HUMAN P15328 CHEMBL2121 Folate Receptor Alpha, Human 18
TYSY_MOUSE P07607 CHEMBL3160 Thymidylate Synthase, Mouse 6
PUR9_HUMAN P31939 CHEMBL2518 AICAR Transformylase, Human 3
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 3
PUR9_MOUSE Q9CWJ9 CHEMBL2277 AICAR Transformylase, Mouse 2
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1
DYR_ECOLI P0ABQ4 CHEMBL1809 Dihydrofolate Reductase, Ecoli 1
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1
DYR_RAT Q920D2 CHEMBL2363 Dihydrofolate Reductase, Rat 1
FOLC_MOUSE P48760 CHEMBL2890 Folylpoly-gamma-glutamate Synthetase, Mouse 1
TYSY_ECOLI P0A884 CHEMBL2555 Thymidylate Synthase, Ecoli 1
TYSY_LACCA P00469 CHEMBL5328 Thymidylate Synthase, Lacca 1
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 1
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 1