ZINC 12

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Swissprot:: THER_BACTH
Stitch:: THER_BACTH
UniProt:: P00800
ChEMBL:: CHEMBL3392
PDB:: 1FJ3 (DOCK); 1FJO (DOCK); 1FJQ (DOCK); 1FJT (DOCK); 1FJU (DOCK); 1FJV (DOCK); 1FJW (DOCK); 1GXW (DOCK); 1HYT (DOCK); 1KEI (DOCK); 1KJO (DOCK); 1KJP (DOCK); 1KKK (DOCK); 1KL6 (DOCK); 1KR6 (DOCK); 1KRO (DOCK); 1KS7 (DOCK); 1KTO (DOCK); 1L3F (DOCK); 1LNA (DOCK); 1LNB (DOCK); 1LNC (DOCK); 1LND (DOCK); 1LNE (DOCK); 1LNF (DOCK); 1OS0 (DOCK); 1PE5 (DOCK); 1PE7 (DOCK); 1PE8 (DOCK); 1QF0 (DOCK); 1QF1 (DOCK); 1QF2 (DOCK); 1THL (DOCK); 1TLI (DOCK); 1TLP (DOCK); 1TLX (DOCK); 1TMN (DOCK); 1TRL (DOCK); 1Y3G (DOCK); 1Z9G (DOCK); 1ZDP (DOCK); 2A7G (DOCK); 2G4Z (DOCK); 2TLI (DOCK); 2TLX (DOCK); 2TMN (DOCK); 2WHZ (DOCK); 2WI0 (DOCK); 3DNZ (DOCK); 3DO0 (DOCK); 3DO1 (DOCK); 3DO2 (DOCK); 3EIM (DOCK); 3F28 (DOCK); 3F2P (DOCK); 3FB0 (DOCK); 3FBO (DOCK); 3FCQ (DOCK); 3FGD (DOCK); 3FLF (DOCK); 3FOR (DOCK); 3FV4 (DOCK); 3FVP (DOCK); 3FWD (DOCK); 3FXP (DOCK); 3FXS (DOCK); 3LS7 (DOCK); 3MS3 (DOCK); 3MSA (DOCK); 3MSF (DOCK); 3MSN (DOCK); 3N21 (DOCK); 3NN7 (DOCK); 3P7P (DOCK); 3P7Q (DOCK); 3P7R (DOCK); 3P7S (DOCK); 3P7T (DOCK); 3P7U (DOCK); 3P7V (DOCK); 3P7W (DOCK); 3QGO (DOCK); 3QH1 (DOCK); 3QH5 (DOCK); 3SSB (DOCK); 3T2H (DOCK); 3T2I (DOCK); 3T2J (DOCK); 3TLI (DOCK); 3TMN (DOCK); 4TLI (DOCK); 4TLN (DOCK); 4TMN (DOCK); 5TLI (DOCK); 5TLN (DOCK); 5TMN (DOCK); 6TLI (DOCK); 6TMN (DOCK); 7TLI (DOCK); 7TLN (DOCK); 8TLI (DOCK); 8TLN (DOCK)

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	66	5	3	5
Binding ≤ 1μM	44	2	1	2

Code	Description	Substances	Purchasable	Natural	In Man
THER-1-B	Thermolysin (cluster #1 Of 3), Bacterial	64	4	4	6
THER-2-B	Thermolysin (cluster #2 Of 3), Bacterial	3	2	0	0
THER-3-B	Thermolysin (cluster #3 Of 3), Bacterial	0	0	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
NEP_HUMAN	P08473	CHEMBL1944	Neprilysin, Human	40
ECE1_HUMAN	P42892	CHEMBL4791	Endothelin-converting Enzyme 1, Human	30
ACE_HUMAN	P12821	CHEMBL1808	Angiotensin-converting Enzyme, Human	12
NEP_RAT	P07861	CHEMBL3369	Neprilysin, Rat	4
ACE2_HUMAN	Q9BYF1	CHEMBL3736	Angiotensin-converting Enzyme 2, Human	2
NEP_PIG	P19621	CHEMBL6107	Neprilysin, Pig	2
AMPB_HUMAN	Q9H4A4	CHEMBL2432	Aminopeptidase B, Human	1
AMPE_HUMAN	Q07075	CHEMBL3439	Aminopeptidase A, Human	1
AMPE_PIG	Q95334	CHEMBL4868	Aminopeptidase A, Pig	1
AMPN_HUMAN	P15144	CHEMBL1907	Aminopeptidase N, Human	1
AMPN_PIG	P15145	CHEMBL2590	Aminopeptidase N, Pig	1
DPP2_RAT	Q9EPB1	CHEMBL4352	Dipeptidyl Peptidase II, Rat	1
DPP3_RAT	O55096	CHEMBL2233	Dipeptidyl Peptidase III, Rat	1
DPP4_RAT	P14740	CHEMBL4653	Dipeptidyl Peptidase IV, Rat	1
DPP6_RAT	P46101	CHEMBL4353	Dipeptidyl Peptidase VI, Rat	1
ECE1_BOVIN	P42891	CHEMBL2340	Endothelin-converting Enzyme 1, Bovin	1
LKHA4_HUMAN	P09960	CHEMBL4618	Leukotriene A4 Hydrolase, Human	1