ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (481)
Reactome (0)
Related By:
Pathway (0)
Organism (2)
Gene (1)
Org. Clust. (0)
ChEMBL (33)
Rings (7)

Endothelin-converting Enzyme 1, Human (481 Compounds)

Swissprot:: ECE1_HUMAN
Stitch:: ECE1_HUMAN
UniProt:: P42892
ChEMBL:: CHEMBL4791
PDB:: 3DWB (DOCK); ECE1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	481	4	6	8
Binding ≤ 1μM	369	3	3	6
Functional ≤ 10μM	4	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ECE1_BOVIN	P42891	CHEMBL2340	Endothelin-converting Enzyme 1, Bovin	16	0	1	1
ECE1_RAT	P42893	CHEMBL2676	Endothelin-converting Enzyme 1, Rat	143	4	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ECE2_HUMAN	O60344	CHEMBL5890	Endothelin-converting Enzyme 2, Human	3	1	0	0

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
NEP_HUMAN	P08473	CHEMBL1944	Neprilysin, Human	218
ACE_RAT	P47820	CHEMBL2625	Angiotensin-converting Enzyme, Rat	88
NEP_RAT	P07861	CHEMBL3369	Neprilysin, Rat	36
THER_BACTH	P00800	CHEMBL3392	Thermolysin, Bacth	30
ACE_HUMAN	P12821	CHEMBL1808	Angiotensin-converting Enzyme, Human	27
NEP_PIG	P19621	CHEMBL6107	Neprilysin, Pig	6
MMP13_HUMAN	P45452	CHEMBL280	Matrix Metalloproteinase 13, Human	5
ACE2_HUMAN	Q9BYF1	CHEMBL3736	Angiotensin-converting Enzyme 2, Human	2
ECE1_BOVIN	P42891	CHEMBL2340	Endothelin-converting Enzyme 1, Bovin	2
ACE_RABIT	P12822	CHEMBL4074	Angiotensin-converting Enzyme, Rabit	1
AMPB_HUMAN	Q9H4A4	CHEMBL2432	Aminopeptidase B, Human	1
AMPE_HUMAN	Q07075	CHEMBL3439	Aminopeptidase A, Human	1
AMPE_PIG	Q95334	CHEMBL4868	Aminopeptidase A, Pig	1
AMPN_HUMAN	P15144	CHEMBL1907	Aminopeptidase N, Human	1
AMPN_PIG	P15145	CHEMBL2590	Aminopeptidase N, Pig	1
ANF_HUMAN	P01160	CHEMBL1293193	Atrial Natriuretic Factor, Human	1
DEF1A_ARATH	Q9FV53	CHEMBL1075041	Peptide Deformylase 1A, Chloroplastic, Arath	1
DEFM_HUMAN	Q9HBH1	CHEMBL4647	Peptide Deformylase Mitochondrial, Human	1
DEF_ECOLI	P0A6K3	CHEMBL4976	Peptide Deformylase, Ecoli	1
DEF_STAAM	P68825	CHEMBL2367	Peptide Deformylase, Staam	1
DPP2_RAT	Q9EPB1	CHEMBL4352	Dipeptidyl Peptidase II, Rat	1
DPP3_RAT	O55096	CHEMBL2233	Dipeptidyl Peptidase III, Rat	1
DPP4_RAT	P14740	CHEMBL4653	Dipeptidyl Peptidase IV, Rat	1
DPP6_RAT	P46101	CHEMBL4353	Dipeptidyl Peptidase VI, Rat	1
ECE1_RAT	P42893	CHEMBL2676	Endothelin-converting Enzyme 1, Rat	1
LKHA4_HUMAN	P09960	CHEMBL4618	Leukotriene A4 Hydrolase, Human	1
MMP1_HUMAN	P03956	CHEMBL332	Matrix Metalloproteinase-1, Human	1
MMP2_HUMAN	P08253	CHEMBL333	Matrix Metalloproteinase-2, Human	1
MMP3_HUMAN	P08254	CHEMBL283	Matrix Metalloproteinase 3, Human	1
MMP8_HUMAN	P22894	CHEMBL4588	Matrix Metalloproteinase 8, Human	1
MMP9_HUMAN	P14780	CHEMBL321	Matrix Metalloproteinase 9, Human	1
PRKDC_HUMAN	P78527	CHEMBL3142	DNA-dependent Protein Kinase, Human	1
Q9JN24_ECOLX	Q9JN24	CHEMBL1795101	Peptide Deformylase, Ecolx	1