UCSF

Angiotensin-converting Enzyme 2, Human (205 Compounds)

Swissprot:
ACE2_HUMAN
Stitch:
ACE2_HUMAN
UniProt:
Q9BYF1
ChEMBL:
CHEMBL3736
Reactome:
REACT_147707
PDB:
1R42 (DOCK)
1R4L (DOCK)
1XJP (DOCK)
2AJF (DOCK)
3D0G (DOCK)
3D0H (DOCK)
3D0I (DOCK)
3KBH (DOCK)
ACE2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 205 16 5 5
Binding ≤ 1μM 192 13 5 5

Reactome Network (1)

Reactome ID Description Species
REACT_147707 Metabolism of Angiotensinogen to Angiotensins Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ACE_HUMAN P12821 CHEMBL1808 Angiotensin-converting Enzyme, Human 164
AMPE_HUMAN Q07075 CHEMBL3439 Aminopeptidase A, Human 1
AMPN_HUMAN P15144 CHEMBL1907 Aminopeptidase N, Human 1
NEP_HUMAN P08473 CHEMBL1944 Neprilysin, Human 34
RENI_HUMAN P00797 CHEMBL286 Renin, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACE2_RAT Q5EGZ1 CHEMBL2311 Angiotensin-converting Enzyme-related Carboxypeptidase, Rat 17 3 3 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1,893 166 81 42
ACE_HUMAN P12821 CHEMBL1808 Angiotensin-converting Enzyme, Human 1,168 112 39 37

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ACE_HUMAN P12821 CHEMBL1808 Angiotensin-converting Enzyme, Human 164
NEP_HUMAN P08473 CHEMBL1944 Neprilysin, Human 34
CBPA1_BOVIN P00730 CHEMBL3481 Carboxypeptidase A1, Bovin 16
NEP_RAT P07861 CHEMBL3369 Neprilysin, Rat 15
ACE_RAT P47820 CHEMBL2625 Angiotensin-converting Enzyme, Rat 9
ACE_RABIT P12822 CHEMBL4074 Angiotensin-converting Enzyme, Rabit 4
ECE1_HUMAN P42892 CHEMBL4791 Endothelin-converting Enzyme 1, Human 2
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 2
NEP_PIG P19621 CHEMBL6107 Neprilysin, Pig 2
RENI_HUMAN P00797 CHEMBL286 Renin, Human 2
THER_BACTH P00800 CHEMBL3392 Thermolysin, Bacth 2
ACE2_RAT Q5EGZ1 CHEMBL2311 Angiotensin-converting Enzyme-related Carboxypeptidase, Rat 1
AMPB_HUMAN Q9H4A4 CHEMBL2432 Aminopeptidase B, Human 1
AMPE_HUMAN Q07075 CHEMBL3439 Aminopeptidase A, Human 1
AMPN_HUMAN P15144 CHEMBL1907 Aminopeptidase N, Human 1
DAPE_HAEIN P44514 CHEMBL1075192 Succinyl-diaminopimelate Desuccinylase, Haein 1
LKHA4_HUMAN P09960 CHEMBL4618 Leukotriene A4 Hydrolase, Human 1
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 1