UCSF

Georganics

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 10μM Targets with Highest Number of Available Compounds (22 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
EST1_HUMAN P23141 CHEMBL2265 Acyl coenzyme A:cholesterol acyltransferase 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EST2_HUMAN O00748 CHEMBL3180 Carboxylesterase 2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
MGLL_HUMAN Q99685 CHEMBL4191 Monoglyceride lipase 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 adrenergic receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CAH2_HUMAN P00918 CHEMBL205 Carbonic anhydrase II 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen synthase kinase-3 alpha 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GSK3B_HUMAN P49841 CHEMBL262 Glycogen synthase kinase-3 beta 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
I23O1_HUMAN P14902 CHEMBL4685 Indoleamine 2,3-dioxygenase 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C virus NS3 protease/helicase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPYD_HUMAN Q12882 CHEMBL3172 Dihydropyrimidine dehydrogenase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GABR1_RAT Q9Z0U4 CHEMBL2753 GABA-B receptor 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GABR2_RAT O88871 CHEMBL4686 GABA-B receptor 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HCAR2_HUMAN Q8TDS4 CHEMBL3785 Nicotinic acid receptor 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IMDH2_HUMAN P12268 CHEMBL2002 Inosine-5'-monophosphate dehydrogenase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCA_HUMAN P17252 CHEMBL299 Protein kinase C alpha 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KPCB_HUMAN P05771 CHEMBL3045 Protein kinase C beta 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LEF_BACAN P15917 CHEMBL4372 Anthrax lethal factor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
OXDA_PIG P00371 CHEMBL6172 D-amino-acid oxidase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP1_HUMAN P09874 CHEMBL3105 Poly [ADP-ribose] polymerase-1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104301 Z104301 CHEMBL1907607 GABA-A receptor; anion channel 1 Annotations Catalogs SMILES SDF Mol2 Flexibase