UCSF

SMDC Life Kinase

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 10μM Targets with Highest Number of Available Compounds (72 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
GBRA1_BOVIN P08219 CHEMBL3627 GABA receptor alpha-1 subunit 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA2_BOVIN P10063 CHEMBL2321 GABA receptor alpha-2 subunit 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA3_BOVIN P10064 CHEMBL3628 GABA receptor alpha-3 subunit 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA4_BOVIN P20237 CHEMBL3140 GABA receptor alpha-4 subunit 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRB1_BOVIN P08220 CHEMBL2848 GABA receptor beta-1 subunit 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRG2_BOVIN P22300 CHEMBL5138 GABA receptor gamma-2 subunit 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein kinase receptor FLT3 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human immunodeficiency virus type 1 reverse transcriptase 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a receptor 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 receptor 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP kinase-interacting serine/threonine-protein kinase MNK1 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_RAT P25099 CHEMBL318 Adenosine A1 receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic glutamate receptor 4 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic glutamate receptor 5 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK08_HUMAN P45983 CHEMBL2276 c-Jun N-terminal kinase 1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PRGR_HUMAN P06401 CHEMBL208 Progesterone receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated protein kinase 2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SFRP1_HUMAN Q8N474 CHEMBL5517 Secreted frizzled-related protein 1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated kinase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein kinase ABL 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALDR_RAT P07943 CHEMBL2622 Aldose reductase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFB_HUMAN P27338 CHEMBL2039 Monoamine oxidase B 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein kinase Aurora-A 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein kinase Aurora-C 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible protein kinase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein kinase PCTAIRE-1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent kinase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CHIT_YEAST P29029 CHEMBL1293195 Endochitinase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CLK2_HUMAN P49760 CHEMBL4225 Dual specificity protein kinase CLK2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual specificity protein kinase CLK4 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DAPK2_HUMAN Q9UIK4 CHEMBL3123 Death-associated protein kinase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated protein kinase 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, double-stranded RNA-activated protein kinase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin type-A receptor 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin type-B receptor 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein kinase GAK 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA1_RAT P62813 CHEMBL343 GABA receptor alpha-1 subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA2_RAT P23576 CHEMBL341 GABA receptor alpha-2 subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA5_RAT P19969 CHEMBL300 GABA receptor alpha-5 subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein kinase JAK3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KC1E_HUMAN P49674 CHEMBL4937 Casein kinase I epsilon 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein kinase I gamma 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCC1A_HUMAN Q14012 CHEMBL2493 CaM kinase I alpha 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCC1D_HUMAN Q8IU85 CHEMBL5073 CaM kinase I delta 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCC1G_HUMAN Q96NX5 CHEMBL5258 CaM kinase I gamma 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase kinase beta 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal protein S6 kinase alpha 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal protein S6 kinase alpha 5 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
M3K5_HUMAN Q99683 CHEMBL5285 Mitogen-activated protein kinase kinase kinase 5 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule affinity-regulating kinase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MET_HUMAN P08581 CHEMBL3717 Hepatocyte growth factor receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK09_HUMAN P45984 CHEMBL4179 c-Jun N-terminal kinase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK10_HUMAN P53779 CHEMBL2637 c-Jun N-terminal kinase 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK12_HUMAN P53778 CHEMBL4674 MAP kinase p38 gamma 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP kinase signal-integrating kinase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP13_HUMAN P45452 CHEMBL280 Matrix metalloproteinase 13 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase kinase gamma subunit 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein kinase PIM1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein kinase PIM2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein kinase PLK4 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein kinase 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein kinase 17A 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein kinase 38-like 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein kinase 16 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
STK3_MOUSE Q9JI10 CHEMBL4310 Serine/threonine-protein kinase MST2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein kinase MST1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- and NCK-interacting kinase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TTHY_HUMAN P02766 CHEMBL3194 Transthyretin 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TTK_HUMAN P33981 CHEMBL3983 Dual specificity protein kinase TTK 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ULK3_MOUSE Q3U3Q1 CHEMBL3832 ULK3 kinase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase