UCSF

Tocris

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

ADME/T 10μM Targets with Highest Number of Available Compounds (31 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP1A2_HUMAN P05177 CHEMBL3356 Cytochrome P450 1A2 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_HUMAN Q06278 CHEMBL3257 Aldehyde oxidase 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACHA3_MOUSE Q8R4G9 CHEMBL1255158 Neuronal acetylcholine receptor subunit alpha-3 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACHB4_MOUSE Q8R493 CHEMBL1255157 Neuronal acetylcholine receptor subunit beta-4 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_RAT Q9Z0U5 CHEMBL1641355 Aldehyde oxidase 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP1A1_HUMAN P04798 CHEMBL2231 Cytochrome P450 1A1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2DQ_RAT P10634 CHEMBL2483 Cytochrome P450 2D2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50597 Z50597 CHEMBL376 Rattus norvegicus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_MACFA Q5FB27 CHEMBL1641357 Aldehyde oxidase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_MOUSE O54754 CHEMBL1641354 Aldehyde oxidase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP24A_HUMAN Q07973 CHEMBL4521 Cytochrome P450 24A1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2A2_RAT P15149 CHEMBL3705 Cytochrome P450 2A2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2A5_MOUSE P20852 CHEMBL4085 Cytochrome P450 2A5 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2A6_HUMAN P11509 CHEMBL5282 Cytochrome P450 2A6 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2B6_HUMAN P20813 CHEMBL4729 Cytochrome P450 2B6 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral blood mononuclear cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80005 Z80005 CHEMBL614077 3T3 (Fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80253 Z80253 CHEMBL614342 MEF (Embryonic fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic lung fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80332 Z80332 CHEMBL614198 NFF (Fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80409 Z80409 CHEMBL614385 R2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80901 Z80901 CHEMBL614392 HaCaT (Keratinocytes) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic kidney fibroblasts) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical vein endothelial cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81072 Z81072 CHEMBL397 Jurkat (Acute leukemic T-cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase