UCSF

TimTec Building Blocks

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

ADME/T 10μM Targets with Highest Number of Available Compounds (44 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP1A2_HUMAN P05177 CHEMBL3356 Cytochrome P450 1A2 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP1A1_HUMAN P04798 CHEMBL2231 Cytochrome P450 1A1 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2A6_HUMAN P11509 CHEMBL5282 Cytochrome P450 2A6 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_HUMAN Q06278 CHEMBL3257 Aldehyde oxidase 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2A5_MOUSE P20852 CHEMBL4085 Cytochrome P450 2A5 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2DQ_RAT P10634 CHEMBL2483 Cytochrome P450 2D2 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_RABIT P80456 CHEMBL1641356 Aldehyde oxidase 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_RAT Q9Z0U5 CHEMBL1641355 Aldehyde oxidase 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2CJ_HUMAN P33261 CHEMBL3622 Cytochrome P450 2C19 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80874 Z80874 CHEMBL393 CEM (T-cell leukemia) 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic kidney fibroblasts) 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81135 Z81135 CHEMBL614793 L6 (Skeletal muscle myoblast cells) 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_MACFA Q5FB27 CHEMBL1641357 Aldehyde oxidase 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADO_MOUSE O54754 CHEMBL1641354 Aldehyde oxidase 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2B6_HUMAN P20813 CHEMBL4729 Cytochrome P450 2B6 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2E1_HUMAN P05181 CHEMBL5281 Cytochrome P450 2E1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral blood mononuclear cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic leukemia cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic lung fibroblast cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80583 Z80583 CHEMBL391 Vero (Kidney cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon carcinoma cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81115 Z81115 CHEMBL398 KB (Squamous cell carcinoma) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81244 Z81244 CHEMBL614123 J774 (Macrophage cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical adenocarcinoma cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALBU_HUMAN P02768 CHEMBL3253 Serum albumin 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2DI_RAT Q64680 CHEMBL4982 Cytochrome P450 2D18 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50418 Z50418 CHEMBL612849 Trypanosoma brucei 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50531 Z50531 CHEMBL613135 Caenorhabditis elegans 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80005 Z80005 CHEMBL614077 3T3 (Fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80088 Z80088 CHEMBL613853 CHO (Ovarian cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80178 Z80178 CHEMBL614040 J774.A1 (Macrophage cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80192 Z80192 CHEMBL614709 KM12 (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80548 Z80548 CHEMBL614245 THP-1 (Acute monocytic leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80897 Z80897 CHEMBL614806 H9 (T-lymphoid cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80901 Z80901 CHEMBL614392 HaCaT (Keratinocytes) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase