Note Type	Comments	Provided By
mp	148 - 151	MolMall (formerly Molecular Diversity Preservation International)
MP	167-168o C	Indofine
Melting_Point	167-172?	Alfa-Aesar
Melting_Point	167-172°	Alfa-Aesar
Mp [°C]	168 - 172	Acros Organics
MP	215	TCI
Mp [°C]	216 - 219	Acros Organics
Target	5-HT Receptor	Selleck Chemicals
UniProt Database Links	5H1AA_TAKRU; 5H1AB_TAKRU; 5HT1A_CANFA; 5HT1A_GORGO; 5HT1A_HORSE; 5HT1A_HUMAN; 5HT1A_MOUSE; 5HT1A_PANTR; 5HT1A_PONPY; 5HT1A_RAT; 5HT1A_VULVU; 5HT1A_XENLA; 5HT1B_CANFA; 5HT1B_CAVPO; 5HT1B_CRIGR; 5HT1B_DIDVI; 5HT1B_FELCA; 5HT1B_GORGO; 5HT1B_HORSE; 5HT1B_HUMA	ChEBI
Purity	95%	Fluorochem
Patent Database Links	EP1323429; EP1579873; EP1829582; EP1854785; EP1958631; GB2383581; US2001051623; US2002010207; US2003069269; US2003166724; US2004077706; US2005096326; US2005267038; US2005288342; US2007185145; US2008095711; WO2005041875; WO2005042501; WO2005065192; WO20051	ChEBI
H phrase	H315: Causes skin irritation	Acros Organics
H phrase	H315: Causes skin irritation; H335: May cause respiratory irritation; H301: Toxic if swallowed; H319: Causes serious eye irritation; H361d: Suspected of damaging the unborn child	Acros Organics
H phrase	H371: May cause damage to organs	Acros Organics
therap	neurotransmitter	MicroSource Spectrum
Target	Others	Selleck Chemicals
P phrase	P260: Do not breathe dust/fume/gas/mist/vapors/spray	Acros Organics
P phrase	P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician	Acros Organics
P phrase	P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician; P281: Use personal protective equipment as required; P261: Avoid breathing dust/fume/gas/mist/vapors/spray; P302+ P352: IF ON SKIN: Wash with plenty of soap and water; P280:	Acros Organics
R phrase	R36/37/38: Irritating to eyes, respiratory system and skin.	Acros Organics
R phrase	R36/37/38: Irritating to eyes, respiratory system and skin.; R25: Toxic if swallowed.; R63: Possible risk of harm to the unborn child.	Acros Organics
R phrase	R68/20/21/22: Harmful : possible risk of irreversible effects through inhalation, in contact with skin and if swallowed.	Acros Organics
Reactome Database Links	REACT_15290; REACT_15291; REACT_15338; REACT_15458; REACT_15486; REACT_15503; REACT_15538; REACT_15546; REACT_16879; REACT_16978; REACT_17008; REACT_17039; REACT_1795; REACT_20519; REACT_21354; REACT_22188; REACT_22234; REACT_22239; REACT_22263; REACT_222	ChEBI
S phrase	S22: Do not breathe dust.	Acros Organics
S phrase	S22: Do not breathe dust.; S36/37: Wear suitable protective clothing and gloves.; S24/25: Avoid contact with skin and eyes.	Acros Organics
S phrase	S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.	Acros Organics
S phrase	S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S28A: After contact with skin, wash immediately with plenty of water.; S37/39: Wear suitable gloves and eye/face protection.; S45: In case of accident or i	Acros Organics
Hazard	T: Toxic	Acros Organics
Hazard	XN: Harmful	Acros Organics

Activity (Go SEA)

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
5HT1A-3-E	Serotonin 1a (5-HT1a) Receptor (cluster #3 Of 4), Eukaryotic	Eukaryotes	5	0.89	Binding ≤ 10μM
5HT1B-1-E	Serotonin 1b (5-HT1b) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.89	Binding ≤ 10μM
5HT1D-1-E	Serotonin 1d (5-HT1d) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.89	Binding ≤ 10μM
5HT1E-1-E	Serotonin 1e (5-HT1e) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	4	0.90	Binding ≤ 10μM
5HT1F-1-E	Serotonin 1f (5-HT1f) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.89	Binding ≤ 10μM
5HT2A-2-E	Serotonin 2a (5-HT2a) Receptor (cluster #2 Of 3), Eukaryotic	Eukaryotes	680	0.66	Binding ≤ 10μM
5HT2B-1-E	Serotonin 2b (5-HT2b) Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	680	0.66	Binding ≤ 10μM
5HT2C-1-E	Serotonin 2c (5-HT2c) Receptor (cluster #1 Of 3), Eukaryotic	Eukaryotes	680	0.66	Binding ≤ 10μM
5HT3A-4-E	Serotonin 3a (5-HT3a) Receptor (cluster #4 Of 5), Eukaryotic	Eukaryotes	120	0.75	Binding ≤ 10μM
5HT3B-1-E	Serotonin 3b (5-HT3b) Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	87	0.76	Binding ≤ 10μM
5HT3C-1-E	Serotonin 3c (5-HT3c) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	120	0.75	Binding ≤ 10μM
5HT3D-1-E	Serotonin 3d (5-HT3d) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	120	0.75	Binding ≤ 10μM
5HT3E-1-E	Serotonin 3e (5-HT3e) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	120	0.75	Binding ≤ 10μM
5HT4R-1-E	Serotonin 4 (5-HT4) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	37	0.80	Binding ≤ 10μM
5HT5A-1-E	Serotonin 5a (5-HT5a) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.71	Binding ≤ 10μM
5HT6R-1-E	Serotonin 6 (5-HT6) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	93	0.76	Binding ≤ 10μM
5HT7R-2-E	Serotonin 7 (5-HT7) Receptor (cluster #2 Of 3), Eukaryotic	Eukaryotes	8	0.87	Binding ≤ 10μM
AA3R-4-E	Adenosine Receptor A3 (cluster #4 Of 6), Eukaryotic	Eukaryotes	79	0.76	Binding ≤ 10μM
DRD1-1-E	Dopamine D1 Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	9690	0.54	Binding ≤ 10μM
DRD3-1-E	Dopamine D3 Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	523	0.68	Binding ≤ 10μM
SC6A4-1-E	Serotonin Transporter (cluster #1 Of 4), Eukaryotic	Eukaryotes	740	0.66	Binding ≤ 10μM
5HT1A-1-E	Serotonin 1a (5-HT1a) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	10	0.86	Functional ≤ 10μM
5HT1B-1-E	Serotonin 1b (5-HT1b) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	5	0.89	Functional ≤ 10μM
5HT1D-1-E	Serotonin 1d (5-HT1d) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	5	0.89	Functional ≤ 10μM
5HT1F-1-E	Serotonin 1f (5-HT1f) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	8	0.87	Functional ≤ 10μM
5HT2A-1-E	Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	70	0.77	Functional ≤ 10μM
5HT2B-1-E	Serotonin 2b (5-HT2b) Receptor (cluster #1 Of 2), Eukaryotic	Eukaryotes	6	0.89	Functional ≤ 10μM
5HT2C-1-E	5-hydroxytryptamine Receptor 2C (cluster #1 Of 2), Eukaryotic	Eukaryotes	25	0.82	Functional ≤ 10μM
5HT3A-1-E	Serotonin 3a (5-HT3a) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	500	0.68	Functional ≤ 10μM
5HT4R-1-E	Serotonin 4 (5-HT4) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.90	Functional ≤ 10μM
5HT7R-1-E	Serotonin 7 (5-HT7) Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	15	0.84	Functional ≤ 10μM
DRD2-1-E	Dopamine D2 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	0	0.00	Functional ≤ 10μM
Z50588-4-O	Canis Familiaris (cluster #4 Of 7), Other	Other	210	0.72	Functional ≤ 10μM
Z50592-1-O	Oryctolagus Cuniculus (cluster #1 Of 8), Other	Other	300	0.70	Functional ≤ 10μM
Z50597-10-O	Rattus Norvegicus (cluster #10 Of 12), Other	Other	919	0.65	Functional ≤ 10μM
Z80334-1-O	NG108-15 (Neuroblastoma-glioma Hybrid Cells) (cluster #1 Of 1), Other	Other	298	0.70	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
AA3R_HUMAN	P33765	Adenosine A3 Receptor, Human	79	0.76	Binding ≤ 1μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	523	0.68	Binding ≤ 1μM
5HT1A_RAT	P19327	Serotonin 1a (5-HT1a) Receptor, Rat	1.6	0.95	Binding ≤ 1μM
5HT1A_HUMAN	P08908	Serotonin 1a (5-HT1a) Receptor, Human	0.5	1.00	Binding ≤ 1μM
5HT1A_MOUSE	Q64264	Serotonin 1a (5-HT1a) Receptor, Mouse	5	0.89	Binding ≤ 1μM
5HT1B_HUMAN	P28222	Serotonin 1b (5-HT1b) Receptor, Human	1.1	0.96	Binding ≤ 1μM
5HT1B_RAT	P28564	Serotonin 1b (5-HT1b) Receptor, Rat	1.1	0.96	Binding ≤ 1μM
5HT1D_HUMAN	P28221	Serotonin 1d (5-HT1d) Receptor, Human	0.5	1.00	Binding ≤ 1μM
5HT1D_RAT	P28565	Serotonin 1d (5-HT1d) Receptor, Rat	2	0.94	Binding ≤ 1μM
5HT1E_HUMAN	P28566	Serotonin 1e (5-HT1e) Receptor, Human	4	0.90	Binding ≤ 1μM
5HT1F_RAT	P30940	Serotonin 1f (5-HT1f) Receptor, Rat	2	0.94	Binding ≤ 1μM
5HT2A_HUMAN	P28223	Serotonin 2a (5-HT2a) Receptor, Human	11	0.86	Binding ≤ 1μM
5HT2A_RAT	P14842	Serotonin 2a (5-HT2a) Receptor, Rat	0.3	1.03	Binding ≤ 1μM
5HT2A_MOUSE	P35363	Serotonin 2a (5-HT2a) Receptor, Mouse	500	0.68	Binding ≤ 1μM
5HT2B_MOUSE	Q02152	Serotonin 2b (5-HT2b) Receptor, Mouse	500	0.68	Binding ≤ 1μM
5HT2B_RAT	P30994	Serotonin 2b (5-HT2b) Receptor, Rat	20	0.83	Binding ≤ 1μM
5HT2B_HUMAN	P41595	Serotonin 2b (5-HT2b) Receptor, Human	1.5	0.95	Binding ≤ 1μM
5HT2C_MOUSE	P34968	Serotonin 2c (5-HT2c) Receptor, Mouse	500	0.68	Binding ≤ 1μM
5HT2C_RAT	P08909	Serotonin 2c (5-HT2c) Receptor, Rat	10	0.86	Binding ≤ 1μM
5HT2C_HUMAN	P28335	Serotonin 2c (5-HT2c) Receptor, Human	1.7	0.94	Binding ≤ 1μM
5HT3A_MOUSE	P23979	Serotonin 3a (5-HT3a) Receptor, Mouse	361	0.69	Binding ≤ 1μM
5HT3A_HUMAN	P46098	Serotonin 3a (5-HT3a) Receptor, Human	120	0.75	Binding ≤ 1μM
5HT3A_RAT	P35563	Serotonin 3a (5-HT3a) Receptor, Rat	120	0.75	Binding ≤ 1μM
5HT3B_RAT	Q9JJ16	Serotonin 3b (5-HT3b) Receptor, Rat	120	0.75	Binding ≤ 1μM
5HT3B_MOUSE	Q9JHJ5	Serotonin 3b (5-HT3b) Receptor, Mouse	361	0.69	Binding ≤ 1μM
5HT3B_HUMAN	O95264	Serotonin 3b (5-HT3b) Receptor, Human	120	0.75	Binding ≤ 1μM
5HT3C_HUMAN	Q8WXA8	Serotonin 3c (5-HT3c) Receptor, Human	120	0.75	Binding ≤ 1μM
5HT3D_HUMAN	Q70Z44	Serotonin 3d (5-HT3d) Receptor, Human	120	0.75	Binding ≤ 1μM
5HT3E_HUMAN	A5X5Y0	Serotonin 3e (5-HT3e) Receptor, Human	120	0.75	Binding ≤ 1μM
5HT4R_RAT	Q62758	Serotonin 4 (5-HT4) Receptor, Rat	147	0.74	Binding ≤ 1μM
5HT4R_HUMAN	Q13639	Serotonin 4 (5-HT4) Receptor, Human	100	0.75	Binding ≤ 1μM
5HT4R_CAVPO	O70528	Serotonin 4 (5-HT4) Receptor, Guinea Pig	100	0.75	Binding ≤ 1μM
5HT5A_HUMAN	P47898	Serotonin 5a (5-HT5a) Receptor, Human	110	0.75	Binding ≤ 1μM
5HT5A_MOUSE	P30966	Serotonin 5a (5-HT5a) Receptor, Mouse	150	0.73	Binding ≤ 1μM
5HT6R_HUMAN	P50406	Serotonin 6 (5-HT6) Receptor, Human	100	0.75	Binding ≤ 1μM
5HT7R_RAT	P32305	Serotonin 7 (5-HT7) Receptor, Rat	10	0.86	Binding ≤ 1μM
5HT7R_HUMAN	P34969	Serotonin 7 (5-HT7) Receptor, Human	0.13	1.06	Binding ≤ 1μM
SC6A4_RAT	P31652	Serotonin Transporter, Rat	740	0.66	Binding ≤ 1μM
AA3R_HUMAN	P33765	Adenosine A3 Receptor, Human	79	0.76	Binding ≤ 10μM
DRD1_HUMAN	P21728	Dopamine D1 Receptor, Human	9690	0.54	Binding ≤ 10μM
DRD3_RAT	P19020	Dopamine D3 Receptor, Rat	2338	0.61	Binding ≤ 10μM
DRD3_HUMAN	P35462	Dopamine D3 Receptor, Human	523	0.68	Binding ≤ 10μM
5HT1A_RAT	P19327	Serotonin 1a (5-HT1a) Receptor, Rat	1.6	0.95	Binding ≤ 10μM
5HT1A_HUMAN	P08908	Serotonin 1a (5-HT1a) Receptor, Human	0.5	1.00	Binding ≤ 10μM
5HT1A_MOUSE	Q64264	Serotonin 1a (5-HT1a) Receptor, Mouse	5	0.89	Binding ≤ 10μM
5HT1B_RAT	P28564	Serotonin 1b (5-HT1b) Receptor, Rat	1.1	0.96	Binding ≤ 10μM
5HT1B_HUMAN	P28222	Serotonin 1b (5-HT1b) Receptor, Human	1.1	0.96	Binding ≤ 10μM
5HT1D_RAT	P28565	Serotonin 1d (5-HT1d) Receptor, Rat	2	0.94	Binding ≤ 10μM
5HT1D_HUMAN	P28221	Serotonin 1d (5-HT1d) Receptor, Human	0.5	1.00	Binding ≤ 10μM
5HT1E_HUMAN	P28566	Serotonin 1e (5-HT1e) Receptor, Human	4	0.90	Binding ≤ 10μM
5HT1F_RAT	P30940	Serotonin 1f (5-HT1f) Receptor, Rat	2	0.94	Binding ≤ 10μM
5HT2A_RAT	P14842	Serotonin 2a (5-HT2a) Receptor, Rat	0.3	1.03	Binding ≤ 10μM
5HT2A_MOUSE	P35363	Serotonin 2a (5-HT2a) Receptor, Mouse	500	0.68	Binding ≤ 10μM
5HT2A_HUMAN	P28223	Serotonin 2a (5-HT2a) Receptor, Human	11	0.86	Binding ≤ 10μM
5HT2B_HUMAN	P41595	Serotonin 2b (5-HT2b) Receptor, Human	1.5	0.95	Binding ≤ 10μM
5HT2B_MOUSE	Q02152	Serotonin 2b (5-HT2b) Receptor, Mouse	500	0.68	Binding ≤ 10μM
5HT2B_RAT	P30994	Serotonin 2b (5-HT2b) Receptor, Rat	20	0.83	Binding ≤ 10μM
5HT2C_RAT	P08909	Serotonin 2c (5-HT2c) Receptor, Rat	10	0.86	Binding ≤ 10μM
5HT2C_HUMAN	P28335	Serotonin 2c (5-HT2c) Receptor, Human	1.7	0.94	Binding ≤ 10μM
5HT2C_MOUSE	P34968	Serotonin 2c (5-HT2c) Receptor, Mouse	500	0.68	Binding ≤ 10μM
5HT3A_HUMAN	P46098	Serotonin 3a (5-HT3a) Receptor, Human	120	0.75	Binding ≤ 10μM
5HT3A_RAT	P35563	Serotonin 3a (5-HT3a) Receptor, Rat	120	0.75	Binding ≤ 10μM
5HT3A_MOUSE	P23979	Serotonin 3a (5-HT3a) Receptor, Mouse	361	0.69	Binding ≤ 10μM
5HT3B_RAT	Q9JJ16	Serotonin 3b (5-HT3b) Receptor, Rat	120	0.75	Binding ≤ 10μM
5HT3B_MOUSE	Q9JHJ5	Serotonin 3b (5-HT3b) Receptor, Mouse	361	0.69	Binding ≤ 10μM
5HT3B_HUMAN	O95264	Serotonin 3b (5-HT3b) Receptor, Human	120	0.75	Binding ≤ 10μM
5HT3C_HUMAN	Q8WXA8	Serotonin 3c (5-HT3c) Receptor, Human	120	0.75	Binding ≤ 10μM
5HT3D_HUMAN	Q70Z44	Serotonin 3d (5-HT3d) Receptor, Human	120	0.75	Binding ≤ 10μM
5HT3E_HUMAN	A5X5Y0	Serotonin 3e (5-HT3e) Receptor, Human	120	0.75	Binding ≤ 10μM
5HT4R_RAT	Q62758	Serotonin 4 (5-HT4) Receptor, Rat	147	0.74	Binding ≤ 10μM
5HT4R_CAVPO	O70528	Serotonin 4 (5-HT4) Receptor, Guinea Pig	100	0.75	Binding ≤ 10μM
5HT4R_HUMAN	Q13639	Serotonin 4 (5-HT4) Receptor, Human	100	0.75	Binding ≤ 10μM
5HT5A_MOUSE	P30966	Serotonin 5a (5-HT5a) Receptor, Mouse	150	0.73	Binding ≤ 10μM
5HT5A_HUMAN	P47898	Serotonin 5a (5-HT5a) Receptor, Human	110	0.75	Binding ≤ 10μM
5HT6R_HUMAN	P50406	Serotonin 6 (5-HT6) Receptor, Human	100	0.75	Binding ≤ 10μM
5HT7R_HUMAN	P34969	Serotonin 7 (5-HT7) Receptor, Human	0.13	1.06	Binding ≤ 10μM
5HT7R_RAT	P32305	Serotonin 7 (5-HT7) Receptor, Rat	10	0.86	Binding ≤ 10μM
SC6A4_RAT	P31652	Serotonin Transporter, Rat	740	0.66	Binding ≤ 10μM
Z50588	Z50588	Canis Familiaris	210	0.72	Functional ≤ 10μM
DRD2_HUMAN	P14416	Dopamine D2 Receptor, Human	0.1	1.08	Functional ≤ 10μM
Z80334	Z80334	NG108-15 (Neuroblastoma-glioma Hybrid Cells)	293	0.70	Functional ≤ 10μM
Z50592	Z50592	Oryctolagus Cuniculus	300	0.70	Functional ≤ 10μM
Z50597	Z50597	Rattus Norvegicus	3548.13389	0.59	Functional ≤ 10μM
5HT1A_HUMAN	P08908	Serotonin 1a (5-HT1a) Receptor, Human	1	0.97	Functional ≤ 10μM
5HT1B_HUMAN	P28222	Serotonin 1b (5-HT1b) Receptor, Human	4.67	0.90	Functional ≤ 10μM
5HT1D_HUMAN	P28221	Serotonin 1d (5-HT1d) Receptor, Human	5.2	0.89	Functional ≤ 10μM
5HT1F_HUMAN	P30939	Serotonin 1f (5-HT1f) Receptor, Human	7.9	0.87	Functional ≤ 10μM
5HT2A_RAT	P14842	Serotonin 2a (5-HT2a) Receptor, Rat	351	0.70	Functional ≤ 10μM
5HT2A_HUMAN	P28223	Serotonin 2a (5-HT2a) Receptor, Human	11	0.86	Functional ≤ 10μM
5HT2B_HUMAN	P41595	Serotonin 2b (5-HT2b) Receptor, Human	0.5	1.00	Functional ≤ 10μM
5HT2B_RAT	P30994	Serotonin 2b (5-HT2b) Receptor, Rat	3.5	0.91	Functional ≤ 10μM
5HT2C_RAT	P08909	Serotonin 2c (5-HT2c) Receptor, Rat	2.8	0.92	Functional ≤ 10μM
5HT2C_HUMAN	P28335	Serotonin 2c (5-HT2c) Receptor, Human	0.1	1.08	Functional ≤ 10μM
5HT3A_MOUSE	P23979	Serotonin 3a (5-HT3a) Receptor, Mouse	3400	0.59	Functional ≤ 10μM
5HT3A_HUMAN	P46098	Serotonin 3a (5-HT3a) Receptor, Human	141	0.74	Functional ≤ 10μM
5HT4R_RAT	Q62758	Serotonin 4 (5-HT4) Receptor, Rat	17.1	0.84	Functional ≤ 10μM
5HT4R_HUMAN	Q13639	Serotonin 4 (5-HT4) Receptor, Human	12	0.85	Functional ≤ 10μM
5HT7R_HUMAN	P34969	Serotonin 7 (5-HT7) Receptor, Human	15	0.84	Functional ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description	Species
G alpha (i) signalling events	Taeniopygia guttata Danio rerio Bos taurus Sus scrofa Caenorhabditis elegans Rattus norvegicus Mus musculus Canis familiaris Drosophila melanogaster Homo sapiens Xenopus tropicalis Gallus gallus
G alpha (q) signalling events	Canis familiaris Danio rerio Rattus norvegicus Taeniopygia guttata Bos taurus Sus scrofa Mus musculus Homo sapiens Gallus gallus Xenopus tropicalis
G alpha (s) signalling events	Taeniopygia guttata Bos taurus Rattus norvegicus Xenopus tropicalis Danio rerio Gallus gallus Homo sapiens Canis familiaris Mus musculus Sus scrofa
Ligand-gated ion channel transport	Xenopus tropicalis Bos taurus Canis familiaris Taeniopygia guttata Homo sapiens Caenorhabditis elegans Sus scrofa Danio rerio Drosophila melanogaster
Metabolism of serotonin	Gallus gallus Canis familiaris Mus musculus Dictyostelium discoideum Taeniopygia guttata Sus scrofa Rattus norvegicus Xenopus tropicalis Bos taurus Homo sapiens Danio rerio
Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2	Danio rerio Canis familiaris Dictyostelium discoideum Gallus gallus Rattus norvegicus Mus musculus Sus scrofa Homo sapiens Xenopus tropicalis Taeniopygia guttata Bos taurus
Na+/Cl- dependent neurotransmitter transporters	Xenopus tropicalis Taeniopygia guttata Caenorhabditis elegans Canis familiaris Homo sapiens Bos taurus Drosophila melanogaster Rattus norvegicus Danio rerio Mus musculus Gallus gallus Sus scrofa
Organic cation transport	Gallus gallus Sus scrofa Caenorhabditis elegans Mus musculus Xenopus tropicalis Taeniopygia guttata Canis familiaris Bos taurus Homo sapiens Danio rerio Rattus norvegicus
Platelet degranulation	Homo sapiens
Serotonin and melatonin biosynthesis	Canis familiaris Arabidopsis thaliana Caenorhabditis elegans Danio rerio Bos taurus Mus musculus Sus scrofa Drosophila melanogaster Xenopus tropicalis Homo sapiens Oryza sativa Rattus norvegicus Gallus gallus Taeniopygia guttata
Serotonin clearance from the synaptic cleft	Homo sapiens
Serotonin Neurotransmitter Release Cycle	Gallus gallus Canis familiaris Drosophila melanogaster Sus scrofa Danio rerio Mus musculus Taeniopygia guttata Caenorhabditis elegans Homo sapiens Bos taurus Rattus norvegicus
Serotonin receptors	Sus scrofa Danio rerio Caenorhabditis elegans Homo sapiens Rattus norvegicus Drosophila melanogaster Xenopus tropicalis Gallus gallus Mus musculus Canis familiaris Taeniopygia guttata Bos taurus
Transport of nucleosides and free purine and pyrimidine bases across the plasma	Saccharomyces cerevisiae Homo sapiens Taeniopygia guttata Rattus norvegicus Drosophila melanogaster Danio rerio Sus scrofa Gallus gallus Mus musculus Bos taurus Canis familiaris Caenorhabditis elegans

Reactome Annotations from Targets (via Uniprot)

Description	Species
Adenosine P1 receptors	Homo sapiens (AA3R_HUMAN)
Dopamine receptors	Rattus norvegicus (DRD3_RAT) Homo sapiens (DRD1_HUMAN)
G alpha (i) signalling events	Rattus norvegicus (DRD3_RAT) Homo sapiens (5HT1A_HUMAN) Mus musculus (5HT5A_MOUSE)
G alpha (q) signalling events	Homo sapiens (5HT2A_HUMAN) Rattus norvegicus (5HT2A_RAT) Mus musculus (5HT2C_MOUSE)
G alpha (s) signalling events	Rattus norvegicus (5HT7R_RAT) Homo sapiens (DRD1_HUMAN)
Ligand-gated ion channel transport	Homo sapiens (5HT3E_HUMAN)
Serotonin receptors	Homo sapiens (5HT1A_HUMAN) Mus musculus (5HT5A_MOUSE) Rattus norvegicus (5HT2A_RAT)

Analogs ( Draw Identity 99% 90% 80% 70% )

Synonyms (45)
Vendors (46)
Annotations (25)
Representations (1)
Notes (29)
Targets (98)
Clustered (36)
Reactome (7)
Rings (0)
Analogs (4)