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ATS5_HUMAN - ADAMTS5, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

ADAMTS5, Human (352 Compounds)

Swissprot:
ATS5_HUMAN
Stitch:
ATS5_HUMAN
UniProt:
Q9UNA0
ChEMBL:
CHEMBL2285
Reactome:
REACT_118572
REACT_200626
PDB:
2RJQ (DOCK)
3B8Z (DOCK)
3HY7 (DOCK)
3HY9 (DOCK)
3HYG (DOCK)
3LJT (DOCK)
ADAMTS5

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 352 25 0 2
Binding ≤ 1μM 178 10 0 2

Reactome Network (2)

Reactome ID Description Species
REACT_118572 Degradation of the extracellular matrix Homo sapiens
REACT_200626 O-glycosylation of TSR domain-containing proteins Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ATS1_HUMAN Q9UHI8 CHEMBL5133 ADAMTS1, Human 3
ATS4_HUMAN O75173 CHEMBL2318 ADAMTS4, Human 76
MMP10_HUMAN P09238 CHEMBL4270 Matrix Metalloproteinase 10, Human 1
MMP12_HUMAN P39900 CHEMBL4393 Matrix Metalloproteinase 12, Human 5
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 14
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 43
MMP15_HUMAN P51511 CHEMBL2963 Matrix Metalloproteinase 15, Human 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 23
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 35
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 6
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 3
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 10
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 26

O-glycosylation of TSR domain-containing proteins

Uniprot Swissprot Chembl Description Number Shared
ATS1_HUMAN Q9UHI8 CHEMBL5133 ADAMTS1, Human 3
ATS4_HUMAN O75173 CHEMBL2318 ADAMTS4, Human 76
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ATS5_BOVIN Q9TT92 CHEMBL2673 ADAMTS5, Bovin 42 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ATS1_HUMAN Q9UHI8 CHEMBL5133 ADAMTS1, Human 3 0 0 0
ATS4_HUMAN O75173 CHEMBL2318 ADAMTS4, Human 190 3 0 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ATS4_HUMAN O75173 CHEMBL2318 ADAMTS4, Human 76
MMP14_HUMAN P50281 CHEMBL3869 Matrix Metalloproteinase 14, Human 43
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 35
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 26
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 23
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 14
ADA17_HUMAN P78536 CHEMBL3706 ADAM17, Human 11
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 10
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 6
MMP12_HUMAN P39900 CHEMBL4393 Matrix Metalloproteinase 12, Human 5
ADA17_PIG O77636 CHEMBL3332 ADAM17, Pig 4
ATS1_HUMAN Q9UHI8 CHEMBL5133 ADAMTS1, Human 3
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 3
ATS5_BOVIN Q9TT92 CHEMBL2673 ADAMTS5, Bovin 2
ATS4_BOVIN Q9TT93 CHEMBL3874 ADAMTS4, Bovin 1
MMP10_HUMAN P09238 CHEMBL4270 Matrix Metalloproteinase 10, Human 1
MMP15_HUMAN P51511 CHEMBL2963 Matrix Metalloproteinase 15, Human 1

Most Common Rings