| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 5 | 0 | 0 | 0 |
| Binding ≤ 1μM | 4 | 0 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_75776 | NOD1/2 Signaling Pathway | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| CASP1_HUMAN | P29466 | CHEMBL4801 | Caspase-1, Human | 4 |
| CASP8_HUMAN | Q14790 | CHEMBL3776 | Caspase-8, Human | 4 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CASP4_MOUSE | P70343 | CHEMBL1075276 | Caspase-4, Mouse | 0 | 0 | 0 | 0 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CASP1_HUMAN | P29466 | CHEMBL4801 | Caspase-1, Human | 975 | 16 | 2 | 1 |
| CASP2_HUMAN | P42575 | CHEMBL4884 | Caspase-2, Human | 75 | 2 | 1 | 2 |
| CASP3_HUMAN | P42574 | CHEMBL2334 | Caspase-3, Human | 987 | 29 | 1 | 5 |
| CASP5_HUMAN | P51878 | CHEMBL3131 | Caspase-5, Human | 4 | 0 | 0 | 0 |
| CASP6_HUMAN | P55212 | CHEMBL3308 | Caspase-6, Human | 171 | 7 | 0 | 1 |
| CASP7_HUMAN | P55210 | CHEMBL3468 | Caspase-7, Human | 433 | 10 | 0 | 2 |
| CASP8_HUMAN | Q14790 | CHEMBL3776 | Caspase-8, Human | 444 | 4 | 1 | 2 |
| CASP9_HUMAN | P55211 | CHEMBL2273 | Caspase-9, Human | 11 | 2 | 0 | 0 |
| CASPA_HUMAN | Q92851 | CHEMBL5037 | Caspase-10, Human | 4 | 0 | 0 | 0 |
| CASPE_HUMAN | P31944 | CHEMBL5991 | Caspase-14, Human | 1 | 0 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| CASP6_HUMAN | P55212 | CHEMBL3308 | Caspase-6, Human | 5 |
| CASP1_HUMAN | P29466 | CHEMBL4801 | Caspase-1, Human | 4 |
| CASP3_HUMAN | P42574 | CHEMBL2334 | Caspase-3, Human | 4 |
| CASP5_HUMAN | P51878 | CHEMBL3131 | Caspase-5, Human | 4 |
| CASP7_HUMAN | P55210 | CHEMBL3468 | Caspase-7, Human | 4 |
| CASP8_HUMAN | Q14790 | CHEMBL3776 | Caspase-8, Human | 4 |
| CASPA_HUMAN | Q92851 | CHEMBL5037 | Caspase-10, Human | 4 |
| CASPE_HUMAN | P31944 | CHEMBL5991 | Caspase-14, Human | 1 |
| CATB_HUMAN | P07858 | CHEMBL4072 | Cathepsin B, Human | 1 |
| CATK_HUMAN | P43235 | CHEMBL268 | Cathepsin K, Human | 1 |
| CATL1_HUMAN | P07711 | CHEMBL3837 | Cathepsin L, Human | 1 |
| CATL2_HUMAN | O60911 | CHEMBL3272 | Cathepsin L2, Human | 1 |
| CATS_HUMAN | P25774 | CHEMBL2954 | Cathepsin S, Human | 1 |
| CATZ_HUMAN | Q9UBR2 | CHEMBL4160 | Cathepsin Z, Human | 1 |
| CYSP_TRYCR | P25779 | CHEMBL3563 | Cruzipain, Trycr | 1 |
| PAPA1_CARPA | P00784 | CHEMBL4779 | Papain, Carpa | 1 |
| TPA_HUMAN | P00750 | CHEMBL1873 | Tissue-type Plasminogen Activator, Human | 1 |