ZINC 12

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  ZINC ID or SMILES

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KaironKem

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 1μM Targets with Highest Number of Available Compounds (49 in total)

Name (Uniprot)	Swissprot	ChEMBL	Description	Size	Browse	Download (Annotations)
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a adrenergic receptor	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK1_HUMAN	P06493	CHEMBL308	Cyclin-dependent kinase 1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK5_HUMAN	Q00535	CHEMBL4036	Cyclin-dependent kinase 5	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104294	Z104294	CHEMBL1907600	Cyclin-dependent kinase 5/CDK5 activator 1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
A4_HUMAN	P05067	CHEMBL2487	Beta amyloid A4 protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNA1_HUMAN	P78396	CHEMBL3609	Cyclin A1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNA2_HUMAN	P20248	CHEMBL2582	Cyclin A2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNB1_HUMAN	P14635	CHEMBL2412	G2/mitotic-specific cyclin B1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNB2_HUMAN	O95067	CHEMBL3723	G2/mitotic-specific cyclin B2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNB3_HUMAN	Q8WWL7	CHEMBL3606	G2/mitotic-specific cyclin B3	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNE1_HUMAN	P24864	CHEMBL3617	G1/S-specific cyclin E1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNE2_HUMAN	O96020	CHEMBL2884	G1/S-specific cyclin E2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNH_HUMAN	P51946	CHEMBL2165	Cyclin H	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNT1_HUMAN	O60563	CHEMBL2108	Cyclin T1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CCNT2_HUMAN	O60583	CHEMBL1293321	Cyclin-T2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK16_HUMAN	Q00536	CHEMBL4597	Serine/threonine-protein kinase PCTAIRE-1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK2_HUMAN	P24941	CHEMBL301	Cyclin-dependent kinase 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK4_HUMAN	P11802	CHEMBL331	Cyclin-dependent kinase 4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK7_HUMAN	P50613	CHEMBL3055	Cyclin-dependent kinase 7	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK9_HUMAN	P50750	CHEMBL3116	Cyclin-dependent kinase 9	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CLK2_HUMAN	P49760	CHEMBL4225	Dual specificity protein kinase CLK2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
COMT_RAT	P22734	CHEMBL2372	Catechol O-methyltransferase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CP19A_RAT	P22443	CHEMBL3859	Cytochrome P450 19A1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA1_HUMAN	P14867	CHEMBL1962	GABA receptor alpha-1 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA2_HUMAN	P47869	CHEMBL4956	GABA receptor alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA3_HUMAN	P34903	CHEMBL3026	GABA receptor alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA5_HUMAN	P31644	CHEMBL5112	GABA receptor alpha-5 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRB3_HUMAN	P28472	CHEMBL1847	GABA receptor beta-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRG2_HUMAN	P18507	CHEMBL1788	GABA receptor gamma-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HCAR2_HUMAN	Q8TDS4	CHEMBL3785	Nicotinic acid receptor 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
KC1D_HUMAN	P48730	CHEMBL2828	Casein kinase I delta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
KC1E_HUMAN	P49674	CHEMBL4937	Casein kinase I epsilon	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
MAT1_HUMAN	P51948	CHEMBL5053	CDK-activating kinase assembly factor MAT1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
OXDA_HUMAN	P14920	CHEMBL5485	D-amino-acid oxidase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PPARG_RAT	O88275	CHEMBL4797	Peroxisome proliferator-activated receptor gamma	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRA_HUMAN	P19793	CHEMBL2061	Retinoid X receptor alpha	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRA_RAT	Q05343	CHEMBL4431	Retinoid X receptor alpha	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRB_HUMAN	P28702	CHEMBL1870	Retinoid X receptor beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRB_MOUSE	P28704	CHEMBL4047	Retinoid X receptor beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRB_RAT	P49743	CHEMBL2805	Retinoid X receptor beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRG_HUMAN	P48443	CHEMBL2004	Retinoid X receptor gamma	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRG_MOUSE	P28705	CHEMBL4402	Retinoid X receptor gamma	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
RXRG_RAT	Q5BJR8	CHEMBL4277	Retinoid X receptor gamma	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma opioid receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
TYRO_AGABI	O42713	CHEMBL3318	Tyrosinase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104296	Z104296	CHEMBL1907602	Cyclin-dependent kinase 1/cyclin B1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104299	Z104299	CHEMBL1907605	Cyclin-dependent kinase 2/cyclin E1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase