ZINC 12

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UEFS Natural Products

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 1μM Targets with Highest Number of Available Compounds (46 in total)

Name (Uniprot)	Swissprot	ChEMBL	Description	Size	Browse	Download (Annotations)
CP1B1_HUMAN	Q16678	CHEMBL4878	Cytochrome P450 1B1	4	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ALDR_RAT	P07943	CHEMBL2622	Aldose reductase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSK21_HUMAN	P68400	CHEMBL3629	Casein kinase II alpha	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5NTD_RAT	P21588	CHEMBL1075214	5'-nucleotidase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ABCG2_HUMAN	Q9UNQ0	CHEMBL5393	ATP-binding cassette sub-family G member 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a adrenergic receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b adrenergic receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d adrenergic receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AHR_HUMAN	P35869	CHEMBL3201	Aryl hydrocarbon receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ALDR_HUMAN	P15121	CHEMBL1900	Aldose reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AOFA_BOVIN	P21398	CHEMBL3254	Monoamine oxidase A	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH2_HUMAN	P00918	CHEMBL205	Carbonic anhydrase II	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic anhydrase VII	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic anhydrase IX	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK1_HUMAN	P06493	CHEMBL308	Cyclin-dependent kinase 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSK21_RAT	P19139	CHEMBL2661	Casein kinase II alpha	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSK2B_HUMAN	P67870	CHEMBL2358	Casein kinase II beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSK2B_RAT	P67874	CHEMBL2463	Casein kinase II beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DHB2_HUMAN	P37059	CHEMBL2789	Estradiol 17-beta-dehydrogenase 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ECR_DROME	P34021	CHEMBL5676	Ecdysone receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
EGFR_HUMAN	P00533	CHEMBL203	Epidermal growth factor receptor erbB1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FABP4_HUMAN	P15090	CHEMBL2083	Fatty acid binding protein adipocyte	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FABP5_HUMAN	Q01469	CHEMBL3674	Fatty acid binding protein epidermal	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
I23O1_HUMAN	P14902	CHEMBL4685	Indoleamine 2,3-dioxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
KAPCA_HUMAN	P17612	CHEMBL4101	cAMP-dependent protein kinase alpha-catalytic subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
KAPCB_HUMAN	P22694	CHEMBL2918	cAMP-dependent protein kinase beta-1 catalytic subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
KAPCG_HUMAN	P22612	CHEMBL2743	cAMP-dependent protein kinase, gamma catalytic subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX12_HUMAN	P18054	CHEMBL3687	Arachidonate 12-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX15_RABIT	P12530	CHEMBL4358	Arachidonate 15-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX5_RAT	P12527	CHEMBL312	Arachidonate 5-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
NOX4_HUMAN	Q9NPH5	CHEMBL1250375	NADPH oxidase 4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PGH1_BOVIN	O62664	CHEMBL2860	Cyclooxygenase-1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PGH1_SHEEP	P05979	CHEMBL2949	Cyclooxygenase-1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PIM1_HUMAN	P11309	CHEMBL2147	Serine/threonine-protein kinase PIM1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q43570_TOBAC	Q43570	CHEMBL1293200	Zn finger protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q965D5_PLAFA	Q965D5	CHEMBL4150	Enoyl-acyl-carrier protein reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SC6A3_RAT	P23977	CHEMBL338	Dopamine transporter	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SRC_HUMAN	P12931	CHEMBL267	Tyrosine-protein kinase SRC	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
TYTR_TRYCR	P28593	CHEMBL5131	Trypanothione reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase