UCSF

Matriptase, Human (126 Compounds)

Swissprot:
ST14_HUMAN
Stitch:
ST14_HUMAN
UniProt:
Q9Y5Y6
ChEMBL:
CHEMBL3018
PDB:
1EAW (DOCK)
1EAX (DOCK)
2FMV (DOCK)
2GV6 (DOCK)
2GV7 (DOCK)
3BN9 (DOCK)
3NCL (DOCK)
3NPS (DOCK)
3P8F (DOCK)
3P8G (DOCK)
ST14

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 126 5 3 3
Binding ≤ 1μM 117 4 2 2
Functional ≤ 10μM 2 0 0 0

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 15 14 6 9
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 10 10 5 6
ST1E1_HUMAN P49888 CHEMBL2346 Estrogen Sulfotransferase, Human 2 0 0 0
ST32B_HUMAN Q9NY57 CHEMBL5912 Serine/threonine-protein Kinase 32B, Human 6 6 3 4
ST32C_HUMAN Q86UX6 CHEMBL5405 Serine/threonine-protein Kinase 32C, Human 1 1 1 1
ST38L_HUMAN Q9Y2H1 CHEMBL4851 Serine/threonine-protein Kinase 38-like, Human 6 6 3 4
STA5A_HUMAN P42229 CHEMBL5403 Signal Transducer And Activator Of Transcription 5A, Human 2 1 0 0
STA5B_HUMAN P51692 CHEMBL5817 Signal Transducer And Activator Of Transcription 5B, Human 3 0 0 0
STAT3_HUMAN P40763 CHEMBL4026 Signal Transducer And Activator Of Transcription 3, Human 118 2 1 1
STAT6_HUMAN P42226 CHEMBL5401 Signal Transducer And Activator Of Transcription 6, Human 66 0 0 0
STF1_HUMAN Q13285 CHEMBL4666 Steroidogenic Factor 1, Human 53 28 0 0
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 26 25 14 18
STK11_HUMAN Q15831 CHEMBL5606 Serine/threonine-protein Kinase 11, Human 7 7 2 3
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 11 9 3 6
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 9 9 4 5
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 9 8 3 4
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 11 10 7 8
STK35_HUMAN Q8TDR2 CHEMBL5651 Serine/threonine-protein Kinase 35, Human 1 1 1 1
STK36_HUMAN Q9NRP7 CHEMBL4312 Serine/threonine-protein Kinase 36, Human 13 11 6 7
STK38_HUMAN Q15208 CHEMBL1075155 Serine/threonine-protein Kinase 38, Human 1 1 1 1
STK39_HUMAN Q9UEW8 CHEMBL1163108 STE20/SPS1-related Proline-alanine-rich Protein Kinase, Human 1 1 1 1
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 19 13 6 8
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 13 12 5 8
STS_HUMAN P08842 CHEMBL3559 Steryl-sulfatase Precursor, Human 205 7 3 6

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 108
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 105
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 87
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 74
KLKB1_HUMAN P03952 CHEMBL2000 Plasma Kallikrein, Human 2
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 2
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 2
CAN1_HUMAN P07384 CHEMBL3891 Calpain 1, Human 1
CAN1_PIG P35750 CHEMBL4062 Calpain 1, Pig 1
CATB_BOVIN P07688 CHEMBL2323 Cathepsin B, Bovin 1
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 1
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 1
CATL2_HUMAN O60911 CHEMBL3272 Cathepsin L2, Human 1
CPNS1_PIG P04574 CHEMBL2205 Calpain Small Subunit 1, Pig 1
FA10_BOVIN P00743 CHEMBL3656 Coagulation Factor X, Bovin 1
PLMN_BOVIN P06868 CHEMBL2957 Plasminogen, Bovin 1
PLMN_RAT Q01177 CHEMBL3204 Plasminogen, Rat 1
Q95WR6_LEIDO Q95WR6 CHEMBL4751 Cysteine Protease, Leido 1
Q9N6S8_PLAFA Q9N6S8 CHEMBL5800 Falcipain 2, Plafa 1
Q9NAW4_PLAFA Q9NAW4 CHEMBL1697661 Cysteine Protease Falcipain-3, Plafa 1
Q9NBD4_PLAFA Q9NBD4 CHEMBL5801 Cysteine Protease Falcipain-2, Plafa 1
S100B_HUMAN P04271 CHEMBL4300 S-100 Protein Beta Chain, Human 1
TM11D_HUMAN O60235 CHEMBL1795138 Transmembrane Protease Serine 11D, Human 1
TMPS2_HUMAN O15393 CHEMBL1795140 Transmembrane Protease Serine 2, Human 1
TMPS6_HUMAN Q8IU80 CHEMBL1795139 Transmembrane Protease Serine 6, Human 1
TRY2_BOVIN Q29463 CHEMBL4472 Trypsin II, Bovin 1
TRYG1_HUMAN Q9NRR2 CHEMBL4955 Tryptase Gamma, Human 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1

Most Common Rings