ZINC 12

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ChiralBlock BioScience BB

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 1μM Targets with Highest Number of Available Compounds (77 in total)

Name (Uniprot)	Swissprot	ChEMBL	Description	Size	Browse	Download (Annotations)
CA2D1_MOUSE	O08532	CHEMBL4676	Voltage-gated calcium channel alpha2/delta subunit 1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
S5A1_RAT	P24008	CHEMBL3422	Steroid 5-alpha-reductase 1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
TOP1_HUMAN	P11387	CHEMBL1781	DNA topoisomerase I	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
3BHS2_RAT	P22072	CHEMBL4821	3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
3BHS5_RAT	P27364	CHEMBL4490	3-beta-hydroxysteroid dehydrogenase type III	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal acetylcholine receptor protein alpha-10 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal acetylcholine receptor protein alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA2_RAT	P12389	CHEMBL2584	Neuronal acetylcholine receptor protein alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal acetylcholine receptor protein alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA3_RAT	P04757	CHEMBL3818	Neuronal acetylcholine receptor protein alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_MOUSE	O70174	CHEMBL4457	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_RAT	P09483	CHEMBL307	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA5_RAT	P20420	CHEMBL4960	Neuronal acetylcholine receptor protein alpha-5 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA6_RAT	P43143	CHEMBL4747	Neuronal acetylcholine receptor protein alpha-6 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal acetylcholine receptor protein alpha-7 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal acetylcholine receptor protein alpha-7 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal acetylcholine receptor protein alpha-7 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA9_RAT	P43144	CHEMBL2585	Neuronal acetylcholine receptor protein alpha-9 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA_RAT	P25108	CHEMBL3599	Acetylcholine receptor protein alpha chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine receptor protein alpha chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB2_RAT	P12390	CHEMBL3001	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB3_RAT	P12391	CHEMBL4568	Neuronal acetylcholine receptor protein beta-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal acetylcholine receptor protein beta-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB4_RAT	P12392	CHEMBL2658	Neuronal acetylcholine receptor protein beta-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB_RAT	P25109	CHEMBL2666	Acetylcholine receptor protein beta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine receptor protein beta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine receptor protein delta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine receptor protein gamma chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHP_LYMST	P58154	CHEMBL6084	Acetylcholine-binding protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic acetylcholine receptor M1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACM1_RAT	P08482	CHEMBL276	Muscarinic acetylcholine receptor M1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic acetylcholine receptor M2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACM2_RAT	P10980	CHEMBL309	Muscarinic acetylcholine receptor M2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic acetylcholine receptor M3	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic acetylcholine receptor M4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CATK_HUMAN	P43235	CHEMBL268	Cathepsin K	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CMA1_HUMAN	P23946	CHEMBL4068	Chymase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DPP2_HUMAN	Q9UHL4	CHEMBL3976	Dipeptidyl peptidase II	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DPP4_HUMAN	P27487	CHEMBL284	Dipeptidyl peptidase IV	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DPP4_RAT	P14740	CHEMBL4653	Dipeptidyl peptidase IV	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DPP9_HUMAN	Q86TI2	CHEMBL4793	Dipeptidyl peptidase IX	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA1_HUMAN	P14867	CHEMBL1962	GABA receptor alpha-1 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA2_HUMAN	P47869	CHEMBL4956	GABA receptor alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA3_HUMAN	P34903	CHEMBL3026	GABA receptor alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GBRA4_HUMAN	P48169	CHEMBL2472	GABA receptor alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GRIA1_MOUSE	P23818	CHEMBL3502	Glutamate receptor ionotropic, AMPA 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GRIA2_RAT	P19491	CHEMBL3503	Glutamate receptor ionotropic, AMPA 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GRIA3_RAT	P19492	CHEMBL3504	Glutamate receptor ionotropic, AMPA 3	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GRIA4_RAT	P19493	CHEMBL3505	Glutamate receptor ionotropic, AMPA 4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HMDH_HUMAN	P04035	CHEMBL402	HMG-CoA reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HMDH_MOUSE	Q01237	CHEMBL2764	HMG-CoA reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HMDH_RAT	P51639	CHEMBL3247	HMG-CoA reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PDE3A_HUMAN	Q14432	CHEMBL241	Phosphodiesterase 3A	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PDE3B_HUMAN	Q13370	CHEMBL290	Phosphodiesterase 3B	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PNMT_BOVIN	P10938	CHEMBL2331	Phenylethanolamine N-methyltransferase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q8BGP7_MOUSE	Q8BGP7	CHEMBL2235	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
S5A1_HUMAN	P18405	CHEMBL1787	Steroid 5-alpha-reductase 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
S5A2_HUMAN	P31213	CHEMBL1856	Steroid 5-alpha-reductase 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104281	Z104281	CHEMBL1907587	Neuronal acetylcholine receptor; alpha3/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104283	Z104283	CHEMBL1907589	Neuronal acetylcholine receptor; alpha4/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104284	Z104284	CHEMBL1907590	Neuronal acetylcholine receptor; alpha2/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104285	Z104285	CHEMBL1907591	Neuronal acetylcholine receptor; alpha4/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104286	Z104286	CHEMBL1907592	Neuronal acetylcholine receptor; alpha2/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104287	Z104287	CHEMBL1907593	Neuronal acetylcholine receptor; alpha3/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104288	Z104288	CHEMBL1907594	Neuronal acetylcholine receptor; alpha3/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104289	Z104289	CHEMBL1907595	Neuronal acetylcholine receptor; alpha4/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104290	Z104290	CHEMBL1907596	Neuronal acetylcholine receptor; alpha4/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104301	Z104301	CHEMBL1907607	GABA-A receptor; anion channel	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104303	Z104303	CHEMBL1907609	Muscarinic acetylcholine receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104304	Z104304	CHEMBL1907610	Adrenergic receptor alpha-1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z50594	Z50594	CHEMBL375	Mus musculus	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase