UCSF

Chemical Block BB

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Functional 10μM Targets with Highest Number of Available Compounds (64 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
Z50597 Z50597 CHEMBL376 Rattus norvegicus 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425 Z50425 CHEMBL364 Plasmodium falciparum 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
HCAR2_HUMAN Q8TDS4 CHEMBL3785 Nicotinic acid receptor 1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587 Z50587 CHEMBL372 Homo sapiens 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50590 Z50590 CHEMBL613488 Sus scrofa 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50594 Z50594 CHEMBL375 Mus musculus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast carcinoma cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian carcinoma cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80712 Z80712 CHEMBL614361 T47D (Breast carcinoma cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic glutamate receptor 6 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
KITH_HUMAN P04183 CHEMBL2883 Thymidine kinase, cytosolic 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5_RAT P12527 CHEMBL312 Arachidonate 5-lipoxygenase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
P97706_RAT P97706 CHEMBL4957 Sodium channel protein type VI alpha subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine transporter 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_RAT P23977 CHEMBL338 Dopamine transporter 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_RAT P31652 CHEMBL313 Serotonin transporter 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium channel protein type II alpha subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SCN2A_RAT P04775 CHEMBL3399 Sodium channel protein type II alpha subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SCN5A_RAT P15389 CHEMBL3866 Sodium channel protein type V alpha subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TPOR_HUMAN P40238 CHEMBL1864 Thrombopoietin receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRPM8_HUMAN Q7Z2W7 CHEMBL1075319 Transient receptor potential cation channel subfamily M member 8 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z101821 Z101821 CHEMBL612765 H2N2 subtype 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z102222 Z102222 CHEMBL613424 Plasma 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z102352 Z102352 CHEMBL613652 Plasma 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z103176 Z103176 CHEMBL1075346 Entamoeba invadens 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA receptor; GRIN1/GRIN2B 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104298 Z104298 CHEMBL1907604 Glutamate NMDA receptor; GRIN1/GRIN2A 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50422 Z50422 CHEMBL612853 Entamoeba histolytica 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50467 Z50467 CHEMBL612884 Trichomonas vaginalis 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50468 Z50468 CHEMBL612652 Giardia intestinalis 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50512 Z50512 CHEMBL369 Cavia porcellus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50606 Z50606 CHEMBL613497 Hepatitis B virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607 Z50607 CHEMBL378 Human immunodeficiency virus 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50641 Z50641 CHEMBL613730 West Nile virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643 Z50643 CHEMBL379 Hepatitis C virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50677 Z50677 CHEMBL613758 Human immunodeficiency virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50678 Z50678 CHEMBL612679 Respiratory syncytial virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50681 Z50681 CHEMBL613761 Duck hepatitis B virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50725 Z50725 CHEMBL612348 Trypanosoma brucei rhodesiense 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80166 Z80166 CHEMBL384 HT-29 (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80211 Z80211 CHEMBL614721 LoVo (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80231 Z80231 CHEMBL614328 MCF7S (Breast carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine sarcoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80347 Z80347 CHEMBL614208 NUGC-3 (Gastric carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80362 Z80362 CHEMBL389 P388 (Lymphoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80466 Z80466 CHEMBL614907 SF268 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80583 Z80583 CHEMBL391 Vero (Kidney cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81011 Z81011 CHEMBL614840 human cell lines 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small cell lung carcinoma) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81115 Z81115 CHEMBL398 KB (Squamous cell carcinoma) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase