In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 11th, 2004 | 22 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.33 | 2.67 | -39.39 | 1 | 2 | 1 | 21 | 302.482 | 8 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT1A-1-E | Serotonin 1a (5-HT1a) Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 280 | 0.42 | Binding ≤ 10μM |
5HT1B-1-E | Serotonin 1b (5-HT1b) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
5HT2A-1-E | Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
5HT2B-2-E | Serotonin 2b (5-HT2b) Receptor (cluster #2 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
5HT2C-2-E | Serotonin 2c (5-HT2c) Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
5HT3A-1-E | Serotonin 3a (5-HT3a) Receptor (cluster #1 Of 5), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
5HT4R-1-E | Serotonin 4 (5-HT4) Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
5HT7R-1-E | Serotonin 7 (5-HT7) Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
AA1R-3-E | Adenosine A1 Receptor (cluster #3 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
AA2AR-2-E | Adenosine A2a Receptor (cluster #2 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
AA3R-3-E | Adenosine Receptor A3 (cluster #3 Of 6), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
ACES-10-E | Acetylcholinesterase (cluster #10 Of 12), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
ACM1-2-E | Muscarinic Acetylcholine Receptor M1 (cluster #2 Of 5), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
ACM2-3-E | Muscarinic Acetylcholine Receptor M2 (cluster #3 Of 6), Eukaryotic | Eukaryotes | 980 | 0.38 | Binding ≤ 10μM |
ACM3-1-E | Muscarinic Acetylcholine Receptor M3 (cluster #1 Of 5), Eukaryotic | Eukaryotes | 2800 | 0.35 | Binding ≤ 10μM |
ACM4-1-E | Muscarinic Acetylcholine Receptor M4 (cluster #1 Of 6), Eukaryotic | Eukaryotes | 1400 | 0.37 | Binding ≤ 10μM |
ACM5-2-E | Muscarinic Acetylcholine Receptor M5 (cluster #2 Of 4), Eukaryotic | Eukaryotes | 4500 | 0.34 | Binding ≤ 10μM |
ADA1A-3-E | Alpha-1a Adrenergic Receptor (cluster #3 Of 3), Eukaryotic | Eukaryotes | 18 | 0.49 | Binding ≤ 10μM |
ADA1B-1-E | Alpha-1b Adrenergic Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 65 | 0.46 | Binding ≤ 10μM |
ADA1D-1-E | Alpha-1d Adrenergic Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 40 | 0.47 | Binding ≤ 10μM |
ADA2A-3-E | Alpha-2a Adrenergic Receptor (cluster #3 Of 4), Eukaryotic | Eukaryotes | 530 | 0.40 | Binding ≤ 10μM |
ADA2B-1-E | Alpha-2b Adrenergic Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 840 | 0.39 | Binding ≤ 10μM |
ADRB1-1-E | Beta-1 Adrenergic Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
ADRB2-1-E | Beta-2 Adrenergic Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
AOFA-1-E | Monoamine Oxidase A (cluster #1 Of 8), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
CNR1-1-E | Cannabinoid CB1 Receptor (cluster #1 Of 5), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
DRD1-1-E | Dopamine D1 Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
DRD3-1-E | Dopamine D3 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
EDNRA-1-E | Endothelin Receptor ET-A (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
GASR-1-E | Cholecystokinin B Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
GCR-1-E | Glucocorticoid Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
HRH1-2-E | Histamine H1 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 610 | 0.40 | Binding ≤ 10μM |
HRH2-3-E | Histamine H2 Receptor (cluster #3 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
HRH3-3-E | Histamine H3 Receptor (cluster #3 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
LYN-1-E | Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
MC4R-1-E | Melanocortin Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
MK14-2-E | MAP Kinase P38 Alpha (cluster #2 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
MT3-1-E | Metallothionein-3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
MTR1A-1-E | Melatonin Receptor 1A (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
NISCH-2-E | Nischarin (cluster #2 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
NK1R-1-E | Neurokinin 1 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
NK2R-1-E | Neurokinin 2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
NPY1R-2-E | Neuropeptide Y Receptor Type 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
NTR1-1-E | Neurotensin Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
OPRK-4-E | Kappa Opioid Receptor (cluster #4 Of 6), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
OPRM-1-E | Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
SC5A7-2-E | High Affinity Choline Transporter 1 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
SC6A2-1-E | Norepinephrine Transporter (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
SC6A3-1-E | Dopamine Transporter (cluster #1 Of 3), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
SC6A4-3-E | Serotonin Transporter (cluster #3 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.38 | Binding ≤ 10μM |
ACM1-3-E | Muscarinic Acetylcholine Receptor M1 (cluster #3 Of 3), Eukaryotic | Eukaryotes | 150 | 0.43 | Functional ≤ 10μM |
DRD2-2-E | Dopamine D2 Receptor (cluster #2 Of 24), Eukaryotic | Eukaryotes | 77 | 0.45 | Binding ≤ 10μM |
Z104283-2-O | Neuronal Acetylcholine Receptor; Alpha4/beta2 (cluster #2 Of 4), Other | Other | 1000 | 0.38 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ACES_HUMAN | P22303 | Acetylcholinesterase, Human | 1000 | 0.38 | Binding ≤ 1μM |
AA1R_HUMAN | P30542 | Adenosine A1 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
AA2AR_HUMAN | P29274 | Adenosine A2a Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
AA3R_HUMAN | P33765 | Adenosine A3 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
ADA1A_HUMAN | P35348 | Alpha-1a Adrenergic Receptor, Human | 18 | 0.49 | Binding ≤ 1μM |
ADA1B_HUMAN | P35368 | Alpha-1b Adrenergic Receptor, Human | 65 | 0.46 | Binding ≤ 1μM |
ADA1D_HUMAN | P25100 | Alpha-1d Adrenergic Receptor, Human | 40 | 0.47 | Binding ≤ 1μM |
ADA2A_HUMAN | P08913 | Alpha-2a Adrenergic Receptor, Human | 530 | 0.40 | Binding ≤ 1μM |
ADA2B_HUMAN | P18089 | Alpha-2b Adrenergic Receptor, Human | 840 | 0.39 | Binding ≤ 1μM |
ADRB1_HUMAN | P08588 | Beta-1 Adrenergic Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
ADRB2_HUMAN | P07550 | Beta-2 Adrenergic Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
CNR1_HUMAN | P21554 | Cannabinoid CB1 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
GASR_HUMAN | P32239 | Cholecystokinin B Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
DRD1_HUMAN | P21728 | Dopamine D1 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
DRD2_HUMAN | P14416 | Dopamine D2 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
DRD3_HUMAN | P35462 | Dopamine D3 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
SC6A3_HUMAN | Q01959 | Dopamine Transporter, Human | 1000 | 0.38 | Binding ≤ 1μM |
EDNRA_HUMAN | P25101 | Endothelin Receptor ET-A, Human | 1000 | 0.38 | Binding ≤ 1μM |
GCR_HUMAN | P04150 | Glucocorticoid Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
SC5A7_HUMAN | Q9GZV3 | High-affinity Choline Transporter, Human | 1000 | 0.38 | Binding ≤ 1μM |
HRH1_HUMAN | P35367 | Histamine H1 Receptor, Human | 610 | 0.40 | Binding ≤ 1μM |
HRH2_HUMAN | P25021 | Histamine H2 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
HRH3_HUMAN | Q9Y5N1 | Histamine H3 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
OPRK_HUMAN | P41145 | Kappa Opioid Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
MK14_HUMAN | Q16539 | MAP Kinase P38 Alpha, Human | 1000 | 0.38 | Binding ≤ 1μM |
MC4R_HUMAN | P32245 | Melanocortin Receptor 4, Human | 1000 | 0.38 | Binding ≤ 1μM |
MTR1A_HUMAN | P48039 | Melatonin Receptor 1A, Human | 1000 | 0.38 | Binding ≤ 1μM |
MT3_HUMAN | P25713 | Metallothionein-3, Human | 1000 | 0.38 | Binding ≤ 1μM |
AOFA_HUMAN | P21397 | Monoamine Oxidase A, Human | 1000 | 0.38 | Binding ≤ 1μM |
OPRM_HUMAN | P35372 | Mu Opioid Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
ACM1_HUMAN | P11229 | Muscarinic Acetylcholine Receptor M1, Human | 1000 | 0.38 | Binding ≤ 1μM |
ACM2_HUMAN | P08172 | Muscarinic Acetylcholine Receptor M2, Human | 1000 | 0.38 | Binding ≤ 1μM |
ACM3_HUMAN | P20309 | Muscarinic Acetylcholine Receptor M3, Human | 1000 | 0.38 | Binding ≤ 1μM |
ACM4_HUMAN | P08173 | Muscarinic Acetylcholine Receptor M4, Human | 1000 | 0.38 | Binding ≤ 1μM |
ACM5_HUMAN | P08912 | Muscarinic Acetylcholine Receptor M5, Human | 1000 | 0.38 | Binding ≤ 1μM |
NK1R_HUMAN | P25103 | Neurokinin 1 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
NK2R_HUMAN | P21452 | Neurokinin 2 Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
Z104283 | Z104283 | Neuronal Acetylcholine Receptor; Alpha4/beta2 | 1000 | 0.38 | Binding ≤ 1μM |
NPY1R_HUMAN | P25929 | Neuropeptide Y Receptor Type 1, Human | 1000 | 0.38 | Binding ≤ 1μM |
NTR1_HUMAN | P30989 | Neurotensin Receptor 1, Human | 1000 | 0.38 | Binding ≤ 1μM |
NISCH_HUMAN | Q9Y2I1 | Nischarin, Human | 1000 | 0.38 | Binding ≤ 1μM |
SC6A2_HUMAN | P23975 | Norepinephrine Transporter, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT1A_HUMAN | P08908 | Serotonin 1a (5-HT1a) Receptor, Human | 280 | 0.42 | Binding ≤ 1μM |
5HT1B_HUMAN | P28222 | Serotonin 1b (5-HT1b) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT2A_HUMAN | P28223 | Serotonin 2a (5-HT2a) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT2B_HUMAN | P41595 | Serotonin 2b (5-HT2b) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT2C_HUMAN | P28335 | Serotonin 2c (5-HT2c) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT3A_HUMAN | P46098 | Serotonin 3a (5-HT3a) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT4R_HUMAN | Q13639 | Serotonin 4 (5-HT4) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
5HT7R_HUMAN | P34969 | Serotonin 7 (5-HT7) Receptor, Human | 1000 | 0.38 | Binding ≤ 1μM |
SC6A4_HUMAN | P31645 | Serotonin Transporter, Human | 1000 | 0.38 | Binding ≤ 1μM |
LYN_HUMAN | P07948 | Tyrosine-protein Kinase Lyn, Human | 1000 | 0.38 | Binding ≤ 1μM |
ACES_HUMAN | P22303 | Acetylcholinesterase, Human | 1000 | 0.38 | Binding ≤ 10μM |
AA1R_HUMAN | P30542 | Adenosine A1 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
AA2AR_HUMAN | P29274 | Adenosine A2a Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
AA3R_HUMAN | P33765 | Adenosine A3 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
ADA1A_HUMAN | P35348 | Alpha-1a Adrenergic Receptor, Human | 18 | 0.49 | Binding ≤ 10μM |
ADA1B_HUMAN | P35368 | Alpha-1b Adrenergic Receptor, Human | 65 | 0.46 | Binding ≤ 10μM |
ADA1D_HUMAN | P25100 | Alpha-1d Adrenergic Receptor, Human | 40 | 0.47 | Binding ≤ 10μM |
ADA2A_HUMAN | P08913 | Alpha-2a Adrenergic Receptor, Human | 530 | 0.40 | Binding ≤ 10μM |
ADA2B_HUMAN | P18089 | Alpha-2b Adrenergic Receptor, Human | 840 | 0.39 | Binding ≤ 10μM |
ADRB1_HUMAN | P08588 | Beta-1 Adrenergic Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
ADRB2_HUMAN | P07550 | Beta-2 Adrenergic Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
CNR1_HUMAN | P21554 | Cannabinoid CB1 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
GASR_HUMAN | P32239 | Cholecystokinin B Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
DRD1_HUMAN | P21728 | Dopamine D1 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
DRD2_HUMAN | P14416 | Dopamine D2 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
DRD3_HUMAN | P35462 | Dopamine D3 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
SC6A3_HUMAN | Q01959 | Dopamine Transporter, Human | 1000 | 0.38 | Binding ≤ 10μM |
EDNRA_HUMAN | P25101 | Endothelin Receptor ET-A, Human | 1000 | 0.38 | Binding ≤ 10μM |
GCR_HUMAN | P04150 | Glucocorticoid Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
SC5A7_HUMAN | Q9GZV3 | High-affinity Choline Transporter, Human | 1000 | 0.38 | Binding ≤ 10μM |
HRH1_HUMAN | P35367 | Histamine H1 Receptor, Human | 610 | 0.40 | Binding ≤ 10μM |
HRH2_HUMAN | P25021 | Histamine H2 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
HRH3_HUMAN | Q9Y5N1 | Histamine H3 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
OPRK_HUMAN | P41145 | Kappa Opioid Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
MK14_HUMAN | Q16539 | MAP Kinase P38 Alpha, Human | 1000 | 0.38 | Binding ≤ 10μM |
MC4R_HUMAN | P32245 | Melanocortin Receptor 4, Human | 1000 | 0.38 | Binding ≤ 10μM |
MTR1A_HUMAN | P48039 | Melatonin Receptor 1A, Human | 1000 | 0.38 | Binding ≤ 10μM |
MT3_HUMAN | P25713 | Metallothionein-3, Human | 1000 | 0.38 | Binding ≤ 10μM |
AOFA_HUMAN | P21397 | Monoamine Oxidase A, Human | 1000 | 0.38 | Binding ≤ 10μM |
OPRM_HUMAN | P35372 | Mu Opioid Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
ACM1_HUMAN | P11229 | Muscarinic Acetylcholine Receptor M1, Human | 1000 | 0.38 | Binding ≤ 10μM |
ACM2_HUMAN | P08172 | Muscarinic Acetylcholine Receptor M2, Human | 1000 | 0.38 | Binding ≤ 10μM |
ACM3_HUMAN | P20309 | Muscarinic Acetylcholine Receptor M3, Human | 1000 | 0.38 | Binding ≤ 10μM |
ACM4_HUMAN | P08173 | Muscarinic Acetylcholine Receptor M4, Human | 1000 | 0.38 | Binding ≤ 10μM |
ACM5_HUMAN | P08912 | Muscarinic Acetylcholine Receptor M5, Human | 1000 | 0.38 | Binding ≤ 10μM |
NK1R_HUMAN | P25103 | Neurokinin 1 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
NK2R_HUMAN | P21452 | Neurokinin 2 Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
Z104283 | Z104283 | Neuronal Acetylcholine Receptor; Alpha4/beta2 | 1000 | 0.38 | Binding ≤ 10μM |
NPY1R_HUMAN | P25929 | Neuropeptide Y Receptor Type 1, Human | 1000 | 0.38 | Binding ≤ 10μM |
NTR1_HUMAN | P30989 | Neurotensin Receptor 1, Human | 1000 | 0.38 | Binding ≤ 10μM |
NISCH_HUMAN | Q9Y2I1 | Nischarin, Human | 1000 | 0.38 | Binding ≤ 10μM |
SC6A2_HUMAN | P23975 | Norepinephrine Transporter, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT1A_HUMAN | P08908 | Serotonin 1a (5-HT1a) Receptor, Human | 280 | 0.42 | Binding ≤ 10μM |
5HT1B_HUMAN | P28222 | Serotonin 1b (5-HT1b) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT2A_HUMAN | P28223 | Serotonin 2a (5-HT2a) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT2B_HUMAN | P41595 | Serotonin 2b (5-HT2b) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT2C_HUMAN | P28335 | Serotonin 2c (5-HT2c) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT3A_HUMAN | P46098 | Serotonin 3a (5-HT3a) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT4R_HUMAN | Q13639 | Serotonin 4 (5-HT4) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
5HT7R_HUMAN | P34969 | Serotonin 7 (5-HT7) Receptor, Human | 1000 | 0.38 | Binding ≤ 10μM |
SC6A4_HUMAN | P31645 | Serotonin Transporter, Human | 1000 | 0.38 | Binding ≤ 10μM |
LYN_HUMAN | P07948 | Tyrosine-protein Kinase Lyn, Human | 1000 | 0.38 | Binding ≤ 10μM |
ACM1_HUMAN | P11229 | Muscarinic Acetylcholine Receptor M1, Human | 150 | 0.43 | Functional ≤ 10μM |
Description | Species |
---|---|
Acetylcholine Neurotransmitter Release Cycle | |
Acetylcholine regulates insulin secretion | |
activated TAK1 mediates p38 MAPK activation | |
Activation of PPARGC1A (PGC-1alpha) by phosphorylation | |
Activation of the AP-1 family of transcription factors | |
Adenosine P1 receptors | |
ADP signalling through P2Y purinoceptor 1 | |
Adrenaline signalling through Alpha-2 adrenergic receptor | |
Adrenaline,noradrenaline inhibits insulin secretion | |
Adrenoceptors | |
Antigen activates B Cell Receptor (BCR) leading to generation of second messenge | |
BMAL1:CLOCK,NPAS2 activates circadian gene expression | |
CD28 co-stimulation | |
CDO in myogenesis | |
Cell surface interactions at the vascular wall | |
Class A/1 (Rhodopsin-like receptors) | |
CTLA4 inhibitory signaling | |
Dopamine clearance from the synaptic cleft | |
Dopamine receptors | |
DSCAM interactions | |
Enzymatic degradation of dopamine by COMT | |
Enzymatic degradation of Dopamine by monoamine oxidase | |
EPH-ephrin mediated repulsion of cells | |
EPH-Ephrin signaling | |
EPHA-mediated growth cone collapse | |
EPHB-mediated forward signaling | |
ERK/MAPK targets | |
Fc epsilon receptor (FCERI) signaling | |
FCERI mediated Ca+2 mobilization | |
FCERI mediated MAPK activation | |
FCERI mediated NF-kB activation | |
FCGR activation | |
G alpha (12/13) signalling events | |
G alpha (i) signalling events | |
G alpha (q) signalling events | |
G alpha (s) signalling events | |
G alpha (z) signalling events | |
G-protein activation | |
Gastrin-CREB signalling pathway via PKC and MAPK | |
GPVI-mediated activation cascade | |
Growth hormone receptor signaling | |
Histamine receptors | |
KSRP destabilizes mRNA | |
Ligand-gated ion channel transport | |
Metabolism of serotonin | |
Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 | |
Muscarinic acetylcholine receptors | |
Na+/Cl- dependent neurotransmitter transporters | |
Neurotransmitter Clearance In The Synaptic Cleft | |
NGF-independant TRKA activation | |
NOD1/2 Signaling Pathway | |
Norepinephrine Neurotransmitter Release Cycle | |
Opioid Signalling | |
Oxidative Stress Induced Senescence | |
p38MAPK events | |
PECAM1 interactions | |
Peptide ligand-binding receptors | |
Platelet Adhesion to exposed collagen | |
Platelet sensitization by LDL | |
Regulation of KIT signaling | |
Regulation of signaling by CBL | |
Role of LAT2/NTAL/LAB on calcium mobilization | |
Serotonin receptors | |
Signaling by SCF-KIT | |
Synthesis of PC | |
Synthesis, secretion, and deacylation of Ghrelin | |
Tachykinin receptors bind tachykinins | |
Transport of glucose and other sugars, bile salts and organic acids, metal ions | |
VEGFA-VEGFR2 Pathway |
No pre-computed analogs available. Try a structural similarity search.