ZINC 12

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  ZINC ID or SMILES

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Life Chemicals Building Blocks

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 1μM Targets with Highest Number of Available Compounds (87 in total)

Name (Uniprot)	Swissprot	ChEMBL	Description	Size	Browse	Download (Annotations)
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) receptor	8	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CA2D1_MOUSE	O08532	CHEMBL4676	Voltage-gated calcium channel alpha2/delta subunit 1	7	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) receptor	6	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) receptor	6	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) receptor	6	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) receptor	6	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal acetylcholine receptor protein alpha-10 subunit	4	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HCAR2_RAT	Q80Z39	CHEMBL4731	HM74 nicotinic acid GPCR	4	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104290	Z104290	CHEMBL1907596	Neuronal acetylcholine receptor; alpha4/beta2	4	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal acetylcholine receptor protein alpha-4 subunit	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal acetylcholine receptor protein alpha-7 subunit	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB4_RAT	P12392	CHEMBL2658	Neuronal acetylcholine receptor protein beta-4 subunit	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a adrenergic receptor	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104283	Z104283	CHEMBL1907589	Neuronal acetylcholine receptor; alpha4/beta2	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) receptor	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) receptor	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH1_HUMAN	P00915	CHEMBL261	Carbonic anhydrase I	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 receptor	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
EST1_HUMAN	P23141	CHEMBL2265	Acyl coenzyme A:cholesterol acyltransferase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HCAR2_HUMAN	Q8TDS4	CHEMBL3785	Nicotinic acid receptor 1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HYES_HUMAN	P34913	CHEMBL2409	Epoxide hydratase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
NOS1_HUMAN	P29475	CHEMBL3568	Nitric-oxide synthase, brain	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
OXDA_HUMAN	P14920	CHEMBL5485	D-amino-acid oxidase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PCP_HUMAN	P42785	CHEMBL2335	Lysosomal Pro-X carboxypeptidase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q72547_9HIV1	Q72547	CHEMBL247	Human immunodeficiency virus type 1 reverse transcriptase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine transporter	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma opioid receptor	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104301	Z104301	CHEMBL1907607	GABA-A receptor; anion channel	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5HT3B_MOUSE	Q9JHJ5	CHEMBL3781	Serotonin 3b (5-HT3b) receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
A4_HUMAN	P05067	CHEMBL2487	Beta amyloid A4 protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA2_RAT	P12389	CHEMBL2584	Neuronal acetylcholine receptor protein alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA3_RAT	P04757	CHEMBL3818	Neuronal acetylcholine receptor protein alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_RAT	P09483	CHEMBL307	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine receptor protein alpha chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB2_RAT	P12390	CHEMBL3001	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal acetylcholine receptor protein beta-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine receptor protein beta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHD_HUMAN	Q07001	CHEMBL3011	Acetylcholine receptor protein delta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine receptor protein delta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine receptor protein gamma chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADA2B_BOVIN	O77700	CHEMBL3523	Alpha-2b adrenergic receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ALDR_RAT	P07943	CHEMBL2622	Aldose reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH14_HUMAN	Q9ULX7	CHEMBL3510	Carbonic anhydrase XIV	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH2_HUMAN	P00918	CHEMBL205	Carbonic anhydrase II	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSF1R_HUMAN	P07333	CHEMBL1844	Macrophage colony stimulating factor receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DDR1_HUMAN	Q08345	CHEMBL5319	Epithelial discoidin domain-containing receptor 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
EGFR_HUMAN	P00533	CHEMBL203	Epidermal growth factor receptor erbB1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
F16P1_HUMAN	P09467	CHEMBL3975	Fructose-1,6-bisphosphatase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FYN_HUMAN	P06241	CHEMBL1841	Tyrosine-protein kinase FYN	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GSK3B_HUMAN	P49841	CHEMBL262	Glycogen synthase kinase-3 beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
KIT_HUMAN	P10721	CHEMBL1936	Stem cell growth factor receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LCK_HUMAN	P06239	CHEMBL258	Tyrosine-protein kinase LCK	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
METC_ECOLI	P06721	CHEMBL1075079	Cystathionine beta-lyase metC	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
NOS2_HUMAN	P35228	CHEMBL4481	Nitric oxide synthase, inducible	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
NOS3_HUMAN	P29474	CHEMBL4803	Nitric-oxide synthase, endothelial	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
OXDA_RAT	O35078	CHEMBL5756	D-amino-acid oxidase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
P95276_MYCTU	P95276	CHEMBL1795155	Epoxide hydrolase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PARP1_HUMAN	P09874	CHEMBL3105	Poly [ADP-ribose] polymerase-1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PGFRA_HUMAN	P16234	CHEMBL2007	Platelet-derived growth factor receptor alpha	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PGFRB_HUMAN	P09619	CHEMBL1913	Platelet-derived growth factor receptor beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PNMT_HUMAN	P11086	CHEMBL4617	Phenylethanolamine N-methyltransferase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SC6A4_RAT	P31652	CHEMBL313	Serotonin transporter	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
TGFR1_HUMAN	P36897	CHEMBL4439	TGF-beta receptor type I	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
TYPH_ECOLI	P07650	CHEMBL3726	Thymidine phosphorylase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
VGFR1_HUMAN	P17948	CHEMBL1868	Vascular endothelial growth factor receptor 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
VGFR2_HUMAN	P35968	CHEMBL279	Vascular endothelial growth factor receptor 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
VGFR3_HUMAN	P35916	CHEMBL1955	Vascular endothelial growth factor receptor 3	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104281	Z104281	CHEMBL1907587	Neuronal acetylcholine receptor; alpha3/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104282	Z104282	CHEMBL1907588	Acetylcholine receptor; alpha1/beta1/delta/gamma	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104284	Z104284	CHEMBL1907590	Neuronal acetylcholine receptor; alpha2/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104286	Z104286	CHEMBL1907592	Neuronal acetylcholine receptor; alpha2/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104287	Z104287	CHEMBL1907593	Neuronal acetylcholine receptor; alpha3/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104288	Z104288	CHEMBL1907594	Neuronal acetylcholine receptor; alpha3/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104289	Z104289	CHEMBL1907595	Neuronal acetylcholine receptor; alpha4/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase