ZINC 12

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UMBBD

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 1μM Targets with Highest Number of Available Compounds (118 in total)

Name (Uniprot)	Swissprot	ChEMBL	Description	Size	Browse	Download (Annotations)
CAH2_HUMAN	P00918	CHEMBL205	Carbonic anhydrase II	8	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase	7	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1	4	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2	4	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH6_HUMAN	P23280	CHEMBL3025	Carbonic anhydrase VI	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
B5SU02_9CNID	B5SU02	CHEMBL1075028	Alpha carbonic anhydrase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
C0IX24_9CNID	C0IX24	CHEMBL1649055	Carbonic anhydrase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH12_HUMAN	O43570	CHEMBL3242	Carbonic anhydrase XII	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH1_HUMAN	P00915	CHEMBL261	Carbonic anhydrase I	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic anhydrase IX	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CBPA1_BOVIN	P00730	CHEMBL3481	Carboxypeptidase A1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CBPA1_HUMAN	P15085	CHEMBL2088	Carboxypeptidase A1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CBPA3_HUMAN	P15088	CHEMBL2645	Mast cell carboxypeptidase A	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FABP4_HUMAN	P15090	CHEMBL2083	Fatty acid binding protein adipocyte	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FABP5_HUMAN	Q01469	CHEMBL3674	Fatty acid binding protein epidermal	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
IL8_HUMAN	P10145	CHEMBL2157	Interleukin-8	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q3I4V7_CRYNV	Q3I4V7	CHEMBL1697676	Carbonic anhydrase 2	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q5AJ71_CANAL	Q5AJ71	CHEMBL5337	Carbonic anhydrase	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA receptor	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
5NTD_RAT	P21588	CHEMBL1075214	5'-nucleotidase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA1R_RAT	P25099	CHEMBL318	Adenosine A1 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA2AR_RAT	P30543	CHEMBL302	Adenosine A2a receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AA3R_RAT	P28647	CHEMBL3360	Adenosine A3 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACES_MOUSE	P21836	CHEMBL3198	Acetylcholinesterase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal acetylcholine receptor protein alpha-10 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal acetylcholine receptor protein alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA2_RAT	P12389	CHEMBL2584	Neuronal acetylcholine receptor protein alpha-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal acetylcholine receptor protein alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA3_RAT	P04757	CHEMBL3818	Neuronal acetylcholine receptor protein alpha-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_MOUSE	O70174	CHEMBL4457	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA4_RAT	P09483	CHEMBL307	Neuronal acetylcholine receptor protein alpha-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA5_RAT	P20420	CHEMBL4960	Neuronal acetylcholine receptor protein alpha-5 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA6_RAT	P43143	CHEMBL4747	Neuronal acetylcholine receptor protein alpha-6 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal acetylcholine receptor protein alpha-7 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal acetylcholine receptor protein alpha-7 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal acetylcholine receptor protein alpha-7 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA9_RAT	P43144	CHEMBL2585	Neuronal acetylcholine receptor protein alpha-9 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA_RAT	P25108	CHEMBL3599	Acetylcholine receptor protein alpha chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine receptor protein alpha chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB2_RAT	P12390	CHEMBL3001	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB3_RAT	P12391	CHEMBL4568	Neuronal acetylcholine receptor protein beta-3 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal acetylcholine receptor protein beta-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB4_RAT	P12392	CHEMBL2658	Neuronal acetylcholine receptor protein beta-4 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB_RAT	P25109	CHEMBL2666	Acetylcholine receptor protein beta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine receptor protein beta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine receptor protein delta chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine receptor protein gamma chain	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ACHP_LYMST	P58154	CHEMBL6084	Acetylcholine-binding protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADCY2_RAT	P26769	CHEMBL2958	Adenylate cyclase type II	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADCY3_RAT	P21932	CHEMBL4864	Adenylate cyclase type III	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADCY4_RAT	P26770	CHEMBL2879	Adenylate cyclase type IV	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADCY5_RAT	Q04400	CHEMBL2880	Adenylate cyclase type V	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADCY6_RAT	Q03343	CHEMBL2975	Adenylate cyclase type VI	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ADCY8_RAT	P40146	CHEMBL3082	Adenylate cyclase type VIII	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AK1C3_HUMAN	P42330	CHEMBL4681	Aldo-keto-reductase family 1 member C3	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ALDR_HUMAN	P15121	CHEMBL1900	Aldose reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ALDR_RAT	P07943	CHEMBL2622	Aldose reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
ANDR_RAT	P15207	CHEMBL3072	Androgen Receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AOFA_BOVIN	P21398	CHEMBL3254	Monoamine oxidase A	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
AROA_ECOLI	P0A6D3	CHEMBL5033	5-enolpyruvylshikimate-3-phosphate synthase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH13_HUMAN	Q8N1Q1	CHEMBL3912	Carbonic anhydrase XIII	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH13_MOUSE	Q9D6N1	CHEMBL2186	Carbonic anhydrase XIII	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH3_HUMAN	P07451	CHEMBL2885	Carbonic anhydrase III	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic anhydrase IV	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic anhydrase VII	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CAH_METTE	P40881	CHEMBL3932	Carbonic anhydrase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CDK1_HUMAN	P06493	CHEMBL308	Cyclin-dependent kinase 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CHLE_HUMAN	P06276	CHEMBL1914	Butyrylcholinesterase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CP1B1_HUMAN	Q16678	CHEMBL4878	Cytochrome P450 1B1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSK21_HUMAN	P68400	CHEMBL3629	Casein kinase II alpha	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CSK2B_HUMAN	P67870	CHEMBL2358	Casein kinase II beta	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CYNT_HELPY	O24855	CHEMBL4211	Carbonic anhydrase 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
CYNT_MYCTU	O53573	CHEMBL6068	Carbonic anhydrase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DHB3_HUMAN	P37058	CHEMBL4234	Estradiol 17-beta-dehydrogenase 3	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 receptor	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
DYR_MYCTU	P0A546	CHEMBL6065	Dihydrofolate reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
EGFR_HUMAN	P00533	CHEMBL203	Epidermal growth factor receptor erbB1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
EGLN1_HUMAN	Q9GZT9	CHEMBL5697	Egl nine homolog 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
EST1_HUMAN	P23141	CHEMBL2265	Acyl coenzyme A:cholesterol acyltransferase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FAAH1_MOUSE	O08914	CHEMBL3455	Anandamide amidohydrolase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FABPL_HUMAN	P07148	CHEMBL5421	Fatty acid-binding protein, liver	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FABPL_RAT	P02692	CHEMBL5738	Fatty acid-binding protein, liver	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
FYN_HUMAN	P06241	CHEMBL1841	Tyrosine-protein kinase FYN	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LCK_HUMAN	P06239	CHEMBL258	Tyrosine-protein kinase LCK	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX12_HUMAN	P18054	CHEMBL3687	Arachidonate 12-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX15_RABIT	P12530	CHEMBL4358	Arachidonate 15-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LOX5_RAT	P12527	CHEMBL312	Arachidonate 5-lipoxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
MURA_ECOLI	P0A749	CHEMBL1984	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) receptor subunit zeta 1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
NOX4_HUMAN	Q9NPH5	CHEMBL1250375	NADPH oxidase 4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PIM1_HUMAN	P11309	CHEMBL2147	Serine/threonine-protein kinase PIM1	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PTPRC_HUMAN	P08575	CHEMBL3243	Leukocyte common antigen	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q79MP6_PSEAI	Q79MP6	CHEMBL1293244	Beta-lactamase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q8BGP7_MOUSE	Q8BGP7	CHEMBL2235	Neuronal acetylcholine receptor protein beta-2 subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q965D5_PLAFA	Q965D5	CHEMBL4150	Enoyl-acyl-carrier protein reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
S22A6_MOUSE	Q8VC69	CHEMBL5653	Solute carrier family 22 member 6	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
S5A2_HUMAN	P31213	CHEMBL1856	Steroid 5-alpha-reductase 2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SHBG_HUMAN	P04278	CHEMBL3305	Testis-specific androgen-binding protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104281	Z104281	CHEMBL1907587	Neuronal acetylcholine receptor; alpha3/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104283	Z104283	CHEMBL1907589	Neuronal acetylcholine receptor; alpha4/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104284	Z104284	CHEMBL1907590	Neuronal acetylcholine receptor; alpha2/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104285	Z104285	CHEMBL1907591	Neuronal acetylcholine receptor; alpha4/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104286	Z104286	CHEMBL1907592	Neuronal acetylcholine receptor; alpha2/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104287	Z104287	CHEMBL1907593	Neuronal acetylcholine receptor; alpha3/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104288	Z104288	CHEMBL1907594	Neuronal acetylcholine receptor; alpha3/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104289	Z104289	CHEMBL1907595	Neuronal acetylcholine receptor; alpha4/beta4	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z104290	Z104290	CHEMBL1907596	Neuronal acetylcholine receptor; alpha4/beta2	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z50594	Z50594	CHEMBL375	Mus musculus	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Z50597	Z50597	CHEMBL376	Rattus norvegicus	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase