UCSF

Enolase via KEGG (EFI)

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Functional 10μM Targets with Highest Number of Available Compounds (139 in total)

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
Z50597 Z50597 CHEMBL376 Rattus norvegicus 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50594 Z50594 CHEMBL375 Mus musculus 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425 Z50425 CHEMBL364 Plasmodium falciparum 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587 Z50587 CHEMBL372 Homo sapiens 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA1_RAT P19490 CHEMBL3753 Glutamate receptor ionotropic, AMPA 1 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA3_RAT P19492 CHEMBL3504 Glutamate receptor ionotropic, AMPA 3 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate receptor ionotropic, AMPA 1 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA2_RAT P19491 CHEMBL3503 Glutamate receptor ionotropic, AMPA 2 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA4_RAT P19493 CHEMBL3505 Glutamate receptor ionotropic, AMPA 4 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic glutamate receptor 1 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM1_RAT P23385 CHEMBL4477 Metabotropic glutamate receptor 1 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 receptor A 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 receptor B 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate receptor ionotropic, AMPA 1 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic glutamate receptor 5 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
RXRA_HUMAN P19793 CHEMBL2061 Retinoid X receptor alpha 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
TS1R2_HUMAN Q8TE23 CHEMBL1613741 Taste receptor type 1 member 2 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
TS1R3_HUMAN Q7RTX0 CHEMBL1613742 Taste receptor type 1 member 3 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80548 Z80548 CHEMBL614245 THP-1 (Acute monocytic leukemia cells) 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate receptor ionotropic, AMPA 2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH1_MOUSE P22437 CHEMBL2649 Cyclooxygenase-1 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_MOUSE Q05769 CHEMBL4321 Cyclooxygenase-2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
S6A11_RAT P31647 CHEMBL3598 GABA transporter 3 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
S6A13_RAT P31646 CHEMBL4889 GABA transporter 2 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA receptor 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
BLAT_ECOLX P62593 CHEMBL2065 Beta-lactamase TEM 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
FFAR1_HUMAN O14842 CHEMBL4422 Free fatty acid receptor 1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA1_HUMAN P14867 CHEMBL1962 GABA receptor alpha-1 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA2_HUMAN P47869 CHEMBL4956 GABA receptor alpha-2 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA3_HUMAN P34903 CHEMBL3026 GABA receptor alpha-3 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA4_HUMAN P48169 CHEMBL2472 GABA receptor alpha-4 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA5_HUMAN P31644 CHEMBL5112 GABA receptor alpha-5 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRA6_HUMAN Q16445 CHEMBL2579 GABA receptor alpha-6 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRB3_HUMAN P28472 CHEMBL1847 GABA receptor beta-3 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRG2_HUMAN P18507 CHEMBL1788 GABA receptor gamma-2 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRR2_HUMAN P28476 CHEMBL2375 GABA receptor rho-2 subunit 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPBAR_HUMAN Q8TDU6 CHEMBL5409 G-protein coupled bile acid receptor 1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate receptor ionotropic, AMPA 3 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic glutamate receptor 2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM4_RAT P31423 CHEMBL2787 Metabotropic glutamate receptor 4 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic glutamate receptor 5 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM8_RAT P70579 CHEMBL2718 Metabotropic glutamate receptor 8 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
NEP_RAT P07861 CHEMBL3369 Neprilysin 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R2_MOUSE Q62053 CHEMBL2488 Prostanoid EP2 receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH1_RAT Q63921 CHEMBL4042 Cyclooxygenase-1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_RAT P35355 CHEMBL2977 Cyclooxygenase-2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP receptor 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RARA_HUMAN P10276 CHEMBL2055 Retinoic acid receptor alpha 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RARB_HUMAN P10826 CHEMBL2008 Retinoic acid receptor beta 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RARG_HUMAN P13631 CHEMBL2003 Retinoic acid receptor gamma 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RXRB_HUMAN P28702 CHEMBL1870 Retinoid X receptor beta 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
RXRG_HUMAN P48443 CHEMBL2004 Retinoid X receptor gamma 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
THAS_HUMAN P24557 CHEMBL1835 Thromboxane-A synthase 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
TLR2_HUMAN O60603 CHEMBL4163 Toll-like receptor 2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50185 Z50185 CHEMBL352 Staphylococcus aureus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50426 Z50426 CHEMBL612856 Plasmodium falciparum (isolate K1 / Thailand) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50512 Z50512 CHEMBL369 Cavia porcellus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50591 Z50591 CHEMBL613489 Bos taurus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast leukemia cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic leukemia cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80583 Z80583 CHEMBL391 Vero (Kidney cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
A2AIR5_MOUSE A2AIR5 CHEMBL2562 Glutamate [NMDA] receptor subunit 3A 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AMPC_ENTCL P05364 CHEMBL2725 Beta-lactamase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BLO1_ECOLX P13661 CHEMBL4951 Beta-lactamase OXA-1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
EAA3_HUMAN P43005 CHEMBL2721 Excitatory amino acid transporter 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GABR1_HUMAN Q9UBS5 CHEMBL2064 GABA-B receptor 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRR1_HUMAN P24046 CHEMBL3561 GABA receptor rho-1 subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GBRR3_HUMAN A8MPY1 CHEMBL2394 GABA receptor rho-3 subunit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIK1_RAT P22756 CHEMBL2919 Glutamate receptor ionotropic kainate 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate receptor ionotropic kainate 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIK2_RAT P42260 CHEMBL3607 Glutamate receptor ionotropic kainate 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIK3_RAT P42264 CHEMBL3744 Glutamate receptor ionotropic kainate 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM2_RAT P31421 CHEMBL2851 Metabotropic glutamate receptor 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic glutamate receptor 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM3_RAT P31422 CHEMBL3067 Metabotropic glutamate receptor 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic glutamate receptor 6 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM6_RAT P35349 CHEMBL3842 Metabotropic glutamate receptor 6 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic glutamate receptor 8 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMD3B_MOUSE Q91ZU9 CHEMBL2557 Glutamate [NMDA] receptor subunit 3B 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE1_MOUSE P35436 CHEMBL2521 Glutamate [NMDA] receptor subunit epsilon 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] receptor subunit epsilon 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE2_MOUSE Q01097 CHEMBL3442 Glutamate [NMDA] receptor subunit epsilon 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE3_MOUSE Q01098 CHEMBL3555 Glutamate [NMDA] receptor subunit epsilon 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE4_MOUSE Q03391 CHEMBL2893 Glutamate [NMDA] receptor subunit epsilon 4 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDZ1_MOUSE P35438 CHEMBL2895 Glutamate (NMDA) receptor subunit zeta 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) receptor subunit zeta 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NOS1_RAT P29476 CHEMBL3048 Nitric-oxide synthase, brain 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NOS2_HUMAN P35228 CHEMBL4481 Nitric oxide synthase, inducible 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide synthase, endothelial 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
O3FA1_HUMAN Q5NUL3 CHEMBL5339 G-protein coupled receptor 120 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
OXER1_HUMAN Q8TDS5 CHEMBL1628461 Oxoeicosanoid receptor 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R1_HUMAN P34995 CHEMBL1811 Prostanoid EP1 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R2_RAT Q62928 CHEMBL4909 Prostanoid EP2 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R4_MOUSE P32240 CHEMBL2489 Prostanoid EP4 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PE2R4_RAT P43114 CHEMBL4086 Prostanoid EP4 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PF2R_MOUSE P43117 CHEMBL5000 Prostaglandin F2-alpha receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH1_BOVIN O62664 CHEMBL2860 Cyclooxygenase-1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_BOVIN O62698 CHEMBL3331 Cyclooxygenase-2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome proliferator-activated receptor alpha 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_MOUSE P23204 CHEMBL2128 Peroxisome proliferator-activated receptor alpha 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
RXRA_RAT Q05343 CHEMBL4431 Retinoid X receptor alpha 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
S6A12_RAT P48056 CHEMBL5248 Betaine transporter 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A1_RAT P23978 CHEMBL4054 GABA transporter 1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 receptor 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100704 Z100704 CHEMBL613874 Lactuca sativa 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100741 Z100741 CHEMBL614867 MC9 (Mast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100766 Z100766 CHEMBL613712 Radical scavenging activity 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z102213 Z102213 CHEMBL613416 Blood 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z102317 Z102317 CHEMBL613617 Brain 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104301 Z104301 CHEMBL1907607 GABA-A receptor; anion channel 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50028 Z50028 CHEMBL347 Streptococcus pneumoniae 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50186 Z50186 CHEMBL353 Staphylococcus epidermidis 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50212 Z50212 CHEMBL354 Escherichia coli 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50324 Z50324 CHEMBL612710 Arabidopsis thaliana 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50335 Z50335 CHEMBL613061 Oryza sativa 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50436 Z50436 CHEMBL365 Filobasidiella neoformans 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50466 Z50466 CHEMBL368 Trypanosoma cruzi 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50518 Z50518 CHEMBL613124 Human herpesvirus 4 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50589 Z50589 CHEMBL612670 Felis catus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50592 Z50592 CHEMBL374 Oryctolagus cuniculus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643 Z50643 CHEMBL379 Hepatitis C virus 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80135 Z80135 CHEMBL614296 F9 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80166 Z80166 CHEMBL384 HT-29 (Colon adenocarcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80377 Z80377 CHEMBL614228 PaCa2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80390 Z80390 CHEMBL390 PC-3 (Prostate carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80418 Z80418 CHEMBL612557 RAW264.7 (Monocytic-macrophage leukemia cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast adenocarcinoma) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80530 Z80530 CHEMBL614946 Swiss-3T3 (Fibroblast cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80712 Z80712 CHEMBL614361 T47D (Breast carcinoma cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate carcinoma) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81267 Z81267 CHEMBL614723 Mononuclear cell line 1 Annotations Catalogs SMILES SDF Mol2 Flexibase